90 research outputs found
Spatial Coordination Strategies in Future Ultra-Dense Wireless Networks
Ultra network densification is considered a major trend in the evolution of
cellular networks, due to its ability to bring the network closer to the user
side and reuse resources to the maximum extent. In this paper we explore
spatial resources coordination as a key empowering technology for next
generation (5G) ultra-dense networks. We propose an optimization framework for
flexibly associating system users with a densely deployed network of access
nodes, opting for the exploitation of densification and the control of overhead
signaling. Combined with spatial precoding processing strategies, we design
network resources management strategies reflecting various features, namely
local vs global channel state information knowledge exploitation, centralized
vs distributed implementation, and non-cooperative vs joint multi-node data
processing. We apply these strategies to future UDN setups, and explore the
impact of critical network parameters, that is, the densification levels of
users and access nodes as well as the power budget constraints, to users
performance. We demonstrate that spatial resources coordination is a key factor
for capitalizing on the gains of ultra dense network deployments.Comment: An extended version of a paper submitted to ISWCS'14, Special Session
on Empowering Technologies of 5G Wireless Communication
Optimal trajectories for efficient atomic transport without final excitation
We design optimal harmonic-trap trajectories to transport cold atoms without
final excitation, combining an inverse engineering techniqe based on
Lewis-Riesenfeld invariants with optimal control theory. Since actual traps are
not really harmonic, we keep the relative displacement between the center of
mass and the trap center bounded. Under this constraint, optimal protocols are
found according to different physical criteria. The minimum time solution has a
"bang-bang" form, and the minimum displacement solution is of "bang-off-bang"
form. The optimal trajectories for minimizing the transient energy are also
discussed.Comment: 10 pages, 7 figure
Anti-phase synchronization of phase-reduced oscillators using open-loop control
In this letter, we present an elegant method to build and maintain an
anti-phase configuration of two nonlinear oscillators with different natural
frequencies and dynamics described by the sinusoidal phase-reduced model. The
anti-phase synchronization is achieved using a common input that couples the
oscillators and consists of a sequence of square pulses of appropriate
amplitude and duration. This example provides a proof of principle that
open-loop control can be used to create desired synchronization patterns for
nonlinear oscillators, when feedback is expensive or impossible to obtain
Oxidation of p62 as an evolutionary adaptation to promote autophagy in stress conditions
Ageing and age-related diseases are characterised by increased oxidative and proteotoxic stress, which results in negative effects on cell function and survival. The cell possesses several mechanisms to deal with damaged proteins, including degradation via macroautophagy (hereafter called autophagy). This essential cellular pathway is conserved from yeast to humans and it is well established that its impairment reduces lifespan in multiple model organisms, including worms, flies and mice. In our study, recently published in Nature Communications, we asked if longer lifespan characteristic of higher organisms is the result of evolutionary adaptations to the autophagy machinery. We found that the autophagy receptor p62 can be oxidised leading to its oligomerisation which ultimately promotes autophagy. However this mechanism, present in vertebrates, has been acquired late in evolution. We propose that the ability of p62 to sense reactive oxygen species (ROS) via oxidation, and potentially other similar modifications, may have evolved in higher organisms and contributed to their increased lifespan. Indeed, impairment of this process could result in age-related neurodegeneration in humans
Corticosteroid therapy in regressive autism: Preliminary findings from a retrospective study
Corticosteroid therapy in regressive autism: a retrospective study of effects on the Frequency Modulated Auditory Evoked Response (FMAER), language, and behavior
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