Liver and gallbladder uptake of ICG.

<p>a) Optoacoustic images through the liver. Grayscale image (left) showing anatomy and ROIs for liver (red) and gallbladder (yellow) analysis. b) FCSI image: fluorescence from ICG overlaid in green on color photograph of cryosection of a mouse sacrificed 10 minutes after injection, showing signal in the liver and gallbladder c) Plot of the signal increase in the liver ROI at 800 nm during single wavelength imaging of the ICG injection. Oscillations are mainly due to breathing motion. The scale is normalized to the maximum value. d) Specific (unmixed) signal from ICG after injection in the liver (black) and gallbladder (blue) ROIs. Each curve is normalized to its own maximum value.</p