The COM-Poisson process for stochastic modeling of osmotic inactivation dynamics of Listeria monocytogenes

Controlling harmful microorganisms, such as Listeria monocytogenes, can require reliable inactivation steps, including those providing conditions (e.g., using high salt content) in which the pathogen could be progressively inactivated. Exposure to osmotic stress could result, however, in variation in the number of survivors, which needs to be carefully considered through appropriate dispersion measures for its impact on intervention practices. Variation in the experimental observations is due to uncertainty and biological variability in the microbial response. The Poisson distribution is suitable for modeling the variation of equi-dispersed count data when the naturally occurring randomness in bacterial numbers it is assumed. However, violation of equi-dispersion is quite often evident, leading to over-dispersion, i.e., non-randomness. This article proposes a statistical modeling approach for describing variation in osmotic inactivation of L. monocytogenes Scott A at different initial cell levels. The change of survivors over inactivation time was described as an exponential function in both the Poisson and in the Conway-Maxwell Poisson (COM-Poisson) processes, with the latter dealing with over dispersion through a dispersion parameter. This parameter was modeled to describe the occurrence of non-randomness in the population distribution, even the one emerging with the osmotic treatment. The results revealed that the contribution of randomness to the total variance was dominant only on the lower-count survivors, while at higher counts the non-randomness contribution to the variance was shown to increase the total variance above the Poisson distribution. When the inactivation model was compared with random numbers generated in computer simulation, a good concordance between the experimental and the modeled data was obtained in the COM-Poisson process

Functional fish: improving nutrition for the elderly

Elder people need highly digestible foods that can also provide health benefits even to those suffering from chronic diseases. Furthermore, such foods should be palatable as well as familiar for elder consumers. Fish is a high-protein, low-fat food that potentially provides a range of health promoting effects which may be further improved with suitable approaches in the production systems. The present mini-review intends to report possible aquaculture interventions to enhance the positive impact of fish on elder health and to promote its function in terms of prevention and recovery of specific diseases. Some fish species during their lifespan experience periods of food restrictions that can be mimicked in aquaculture without affecting fish welfare. Under these circumstances fish can modify the fatty acid profile and increase the use of muscle proteins to fulfill their energy requirements, by activation of muscle endogenous proteases. Degradation of muscle proteins can enhance their digestibility and possibly the release of encrypted bioactive peptides, showing a plethora of biological actions, including the antihypertensive activity. The degree of myofibrillar protein degradation and the fatty acid profile of fish fillet can then be managed by suitable and sustainable feeding protocols in the context of farming conditions

Growth of Bacillus cereus on solid media as affected by agar, sodium chloride, and potassium sorbate.

The effect of two independent variables: microstructure, as modified by the agar content (1.0, 4.0, 7.0%), and water activity (a(w)), as modified by the NaCl content (0.5, 2.5, 4.5%), in the absence or in the presence of potassium sorbate (0.0; 2,000 ppm) on Bacillus cereus growth on solid media was studied. The time to visible growth (TVG) and the radial growth rate (RGR) of colonies were evaluated. TVG was not affected by microstructure and K-sorbate, although when a(w) was reduced, TVG tended to increase. RGR depended on linear effects of microstructure and a(w) variables and their interaction. When K-sorbate was added to cultural media, RGR was reduced significantly. However, in the presence of K-sorbate, RGR was found to change only when a(w) vas varied

psort

psort \ue8 stato il pi\uf9 veloce software di ordinamento per macchine di classe PC dal 2008 al 2011 (benchmark Pennysort, http://sortbenchmark.org) e un suo adattamento per cluster ha migliorato il record per il benchmark datamation di quasi un ordine di grandezza nel 2011. Il rapporto tecnico ufficiale si trova sul sito sortbenchmark.org (che cataloga i pi\uf9 efficienti software di ordinamento per varie categorie di task/hardware - originariamente mantenuto dal premio Turing Jim Gray) all'URL http://sortbenchmark.org/psort_2011.pdf -- Ulteriori dettagli si possono trovare nelle pubblicazioni: P. Bertasi, M. Bressan, E. Peserico. psort, yet another fast stable sorting software, ACM Journal of Experimental Algorithmics, vol. 16, 2011 -- P. Bertasi, M. Bonazza, M. Bressan, E. Peserico. Datamation: a quarter of a century and four orders of magnitude later. Proc. of IEEE CLUSTER 201

Huge networks, tiny faulty nodes

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 2007.Includes bibliographical references (p. 87-91).Can one build, and efficiently use, networks of arbitrary size and topology using a "standard" node whose resources, in terms of memory and reliability, do not need to scale up with the complexity and size of the network? This thesis addresses two important aspects of this question. The first is whether one can achieve efficient connectivity despite the presence of a constant probability of faults per node/link. Efficient connectivity means (informally) having every pair of regions connected by a constant fraction of the independent, entirely non-faulty paths that would be present if the entire network were fault free - even at distances where each path has only a vanishingly small probability of being fault-free. The answer is yes, as long as some very mild topological conditions on the high level structure of the network are met - informally, if the network is not too "thin" and if it does not contain too many large "holes". The results go against some established "empyrical wisdom" in the networking community. The second issue addressed by this thesis is whether one can route efficiently on a network of arbitrary size and topology using only a constant number c of bits/node (even if c is less than the logarithm of the network's size!). Routing efficiently means (informally) that message delivery should only stretch the delivery path by a constant factor. The answer again is yes, as long as the volume of the network grows only polynomially with its radius (otherwise, we run into established lower bounds). This effectively captures every network one may build in a universe (like our own) with finite dimensionality using links of a fixed, maximum length and nodes with a fixed, minimum volume. The results extend the current results for compact routing, allowing one to route efficiently on a much larger class of networks than had previously been known, with many fewer bits.by Enoch Peserico.Ph.D

Revised ephemeris and orbital period derivative of the supersoft X-ray source CAL 87 based on 34 years of observations

In this study, we present an analysis of over 34 years of observational data from CAL 87, an eclipsing supersoft X-ray source. The primary aim of our study, which combines previously analysed measurements as well as unexplored publicly available datasets, is to examine the orbital period evolution of CAL 87. After meticulously and consistently determining the eclipse timings, we constructed an O$-$C (observed minus calculated) diagram using a total of 38 data points. Our results provide confirmation of a positive derivative in the system's orbital period, with a determined value of $\dot{P}=+ 8.18\pm1.46\times10^{-11}$ s/s. We observe a noticeable jitter in the eclipse timings and additionally identify a systematic delay in the X-ray eclipses compared to those observed in longer wavelengths. We discuss the interplay of the pertinent factors that could contribute to a positive period derivative and the inherent variability in the eclipses.Comment: 5 pages, 4 figures. Accepted to MNRA