SkyDOT (Sky Database for Objects in the Time Domain): A Virtual Observatory for Variability Studies at LANL

The mining of Virtual Observatories (VOs) is becoming a powerful new method for discovery in astronomy. Here we report on the development of SkyDOT (Sky Database for Objects in the Time domain), a new Virtual Observatory, which is dedicated to the study of sky variability. The site will confederate a number of massive variability surveys and enable exploration of the time domain in astronomy. We discuss the architecture of the database and the functionality of the user interface. An important aspect of SkyDOT is that it is continuously updated in near real time so that users can access new observations in a timely manner. The site will also utilize high level machine learning tools that will allow sophisticated mining of the archive. Another key feature is the real time data stream provided by RAPTOR (RAPid Telescopes for Optical Response), a new sky monitoring experiment under construction at Los Alamos National Laboratory (LANL).Comment: to appear in SPIE proceedings vol. 4846, 11 pages, 5 figure

Instantaneous Normal Mode Analysis of Supercooled Water

We use the instantaneous normal mode approach to provide a description of the local curvature of the potential energy surface of a model for water. We focus on the region of the phase diagram in which the dynamics may be described by the mode-coupling theory. We find, surprisingly, that the diffusion constant depends mainly on the fraction of directions in configuration space connecting different local minima, supporting the conjecture that the dynamics are controlled by the geometric properties of configuration space. Furthermore, we find an unexpected relation between the number of basins accessed in equilibrium and the connectivity between them.Comment: 5 pages, 4 figure

Integrating the Fermi Gamma-Ray Burst Monitor into the 3rd Interplanetary Network

We are integrating the Fermi Gamma-Ray Burst Monitor (GBM) into the Interplanetary Network (IPN) of Gamma-Ray Burst (GRB) detectors. With the GBM, the IPN will comprise 9 experiments. This will 1) assist the Fermi team in understanding and reducing their systematic localization uncertainties, 2) reduce the sizes of the GBM and Large Area Telescope (LAT) error circles by 1 to 4 orders of magnitude, 3) facilitate the identification of GRB sources with objects found by ground- and space-based observatories at other wavelengths, from the radio to very high energy gamma-rays, 4) reduce the uncertainties in associating some LAT detections of high energy photons with GBM bursts, and 5) facilitate searches for non-electromagnetic GRB counterparts, particularly neutrinos and gravitational radiation. We present examples and demonstrate the synergy between Fermi and the IPN. This is a Fermi Cycle 2 Guest Investigator project.Comment: 5 pages, 11 figures. 2009 Fermi Symposium. eConf Proceedings C09112

Interplanetary Network Localization of GRB991208 and the Discovery of its Afterglow

The extremely energetic (~10^-4 erg/cm^2) gamma-ray burst (GRB) of 1999 December 8 was triangulated to a ~14 sq. arcmin. error box ~1.8 d after its arrival at Earth with the 3rd interplanetary network (IPN), consisting of the Ulysses, Near Earth Asteroid Rendezvous (NEAR), and WIND spacecraft. Radio observations with the Very Large Array ~2.7 d after the burst revealed a bright fading counterpart whose position is consistent with that of an optical transient source whose redshift is z=0.707. We present the time history, peak flux, fluence, and refined 1.3 sq. arcmin. error box of this event, and discuss its energetics. This is the first time that a counterpart has been found for a GRB localized only by the IPN.Comment: Revised version, accepted for publication in the Astrophysical Journal Letter

Thermodynamic and structural aspects of the potential energy surface of simulated water

Relations between the thermodynamics and dynamics of supercooled liquids approaching a glass transition have been proposed over many years. The potential energy surface of model liquids has been increasingly studied since it provides a connection between the configurational component of the partition function on one hand, and the system dynamics on the other. This connection is most obvious at low temperatures, where the motion of the system can be partitioned into vibrations within a basin of attraction and infrequent inter-basin transitions. In this work, we present a description of the potential energy surface properties of supercooled liquid water. The dynamics of this model has been studied in great details in the last years. Specifically, we locate the minima sampled by the liquid by ``quenches'' from equilibrium configurations generated via molecular dynamics simulations. We calculate the temperature and density dependence of the basin energy, degeneracy, and shape. The temperature dependence of the energy of the minima is qualitatively similar to simple liquids, but has anomalous density dependence. The unusual density dependence is also reflected in the configurational entropy, the thermodynamic measure of degeneracy. Finally, we study the structure of simulated water at the minima, which provides insight on the progressive tetrahedral ordering of the liquid on cooling

Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

Acknowledgements Generation Scotland has received core funding from the Chief Scientist Office of the Scottish Government Health Directorates CZD/16/6 and the Scottish Funding Council HR03006. We are grateful to all the families who took part, the general practitioners and the Scottish School of Primary Care for their help in recruiting them and the whole Generation Scotland team, which includes interviewers, computer and laboratory technicians, clerical workers, research scientists, volunteers, managers, receptionists, health-care assistants and nurses. We acknowledge with gratitude the financial support received for this work from the Dr Mortimer and Theresa Sackler Foundation. For the Lothian Birth Cohorts (LBC1921 and LBC1936), we thank Paul Redmond for database management assistance; Alan Gow, Martha Whiteman, Alison Pattie, Michelle Taylor, Janie Corley, Caroline Brett and Caroline Cameron for data collection and data entry; nurses and staff at the Wellcome Trust Clinical Research Facility, where blood extraction and genotyping was performed; staff at the Lothian Health Board; and the staff at the SCRE Centre, University of Glasgow. The research was supported by a program grant from Age UK (Disconnected Mind) and by grants from the Biotechnology and Biological Sciences Research Council (BBSRC). The work was undertaken by The University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, part of the cross council Lifelong Health and Wellbeing Initiative (MR/K026992/1). Funding from the Medical Research Council (MRC) and BBSRC is gratefully acknowledged. DJM is an NRS Career Research Fellow funded by the CSO. BATS were funded by the Australian Research Council (A79600334, A79906588, A79801419, DP0212016, DP0664638, and DP1093900) and the National Health and Medical Research Council (389875) Australia. MKL is supported by a Perpetual Foundation Wilson Fellowship. SEM is supported by a Future Fellowship (FT110100548) from the Australian Research Council. GWM is supported by a National Health and Medical Research Council (NHMRC), Australia, Fellowship (619667). We thank the twins and siblings for their participation, Marlene Grace, Ann Eldridge and Natalie Garden for cognitive assessments, Kerrie McAloney, Daniel Park, David Smyth and Harry Beeby for research support, Anjali Henders and staff in the Molecular Epidemiology Laboratory for DNA sample processing and preparation and Scott Gordon for quality control and management of the genotypes. This work is supported by a Stragetic Award from the Wellcome Trust, reference 104036/Z/14/Z.Peer reviewedPublisher PD

The RAPTOR Experiment: A System for Monitoring the Optical Sky in Real Time

The Rapid Telescopes for Optical Response (RAPTOR) experiment is a spatially distributed system of autonomous robotic telescopes that is designed to monitor the sky for optical transients. The core of the system is composed of two telescope arrays, separated by 38 kilometers, that stereoscopically view the same 1500 square-degree field with a wide-field imaging array and a central 4 square-degree field with a more sensitive narrow-field "fovea" imager. Coupled to each telescope array is a real-time data analysis pipeline that is designed to identify interesting transients on timescales of seconds and, when a celestial transient is identified, to command the rapidly slewing robotic mounts to point the narrow-field ``fovea'' imagers at the transient. The two narrow-field telescopes then image the transient with higher spatial resolution and at a faster cadence to gather light curve information. Each "fovea" camera also images the transient through a different filter to provide color information. This stereoscopic monitoring array is supplemented by a rapidly slewing telescope with a low resolution spectrograph for follow-up observations of transients and a sky patrol telescope that nightly monitors about 10,000 square-degrees for variations, with timescales of a day or longer, to a depth about 100 times fainter. In addition to searching for fast transients, we will use the data stream from RAPTOR as a real-time sentinel for recognizing important variations in known sources. Altogether, the RAPTOR project aims to construct a new type of system for discovery in optical astronomy--one that explores the time domain by "mining the sky in real time".Comment: 11 pages, To appear in the Proceedings of the SPIE, Volume 484