Uspostavljanje programa selektivnog uzgoja kalifornijske pastrmke (oncorhynchus mykiss, walbaum) u Srbiji

Zahtev za sve većim količinama hrane za ljudsku upotrebu, efikasnost iskorišćavanja hraniva i prostora za gajenje domaćih životinja, kao i pojava mnogih bolesti doveli su do intenzivnog razvijanja selekcionih programa u svim granama poljoprivrede. Za razliku od ostalih gajenih životinja, programi selekcije u akvakulturi su se razvili nešto kasnije usled nedostatka potrebnih procena heritabilnosti, koeficijenata varijacija i korelacija za ekonomski bitne osobine. Trenutno se u akvakulturi samo 1-2% od ukupne proizvodnje zasniva na genetički unapređenim vrstama riba (Gjedrem, 1997). Korišćenjem selektovanih linija riba postiže se više korisnih stvari. Na prvom mestu, programi selekcije riba predstavljaju jedini način stalnog unapređenja ekonomski bitnih osobina kao sto su prirast, konverzija hrane, otpornost na bolesti, smanjenje masnoće u mesu riba. Ribe iz selektovanih linija efikasnije iskorišćavaju hraniva i na taj način smanjuju pritisak na divlje populacije riba koje se koriste za proizvodnju ribljeg brašna, kao glavnog izvora proteina u smešama za ishranu pastrmki. Ribe koje potiču iz divljine ne napreduju zadovoljavajućim brzinom, što znači da su konstantno pod stresom, za razliku od riba poreklom iz selekcionih programa koje pokazuju manji uticaj stresa usled gajenja u zarobljeništvu. Tako se na ovaj način korišćenjem selektovanih linija riba postiže efikasna i održiva proizvodnja uz vođenje računa o dobrobiti životinja. Drugi dobar razlog za uspostavljanje programa selekcije pastrmke u Srbiji je dobro dokumentovano postojanje interakcije genotip x okolina kod kalifornijske pastrmke, kao što su pokazala istraživanja (McKay et al., 1984; Hanke et al., 1989; Sylven et al., 1991; Winkelman and Peterson, 1994; Kettunen et al., 1999; Kause et al., 2003). Na kraju, ali ne i najmanje važna je i kontrola bolesti kod kalifornijske pastrmke i mogućnost stvaranja otpornih linija pastrmki na neke bolesti putem selektivnog uzgoja (Henrion, 2005). Jedno od rešenja za ovaj ozbiljan problem, pored boljeg sistema kontrole pastrmske ikre poreklom iz uvoza, je i stvaranje lokalnih selektovanih matičnih jata sa proverenim poreklom i povećenom otpornošću na bolesti. Obzirom da za kalifornijsku pastrmku postoje pouzdani podaci o varijabilnosti i heritabilnosti proizvodnih osobina ovo pruža mogućnost efikasne selekcije, a samom tim i značajnog unapređenja proizvodnje uz smanjen ukupni mortalitet, putem odgovarajućeg programa selekcije u Srbiji

Akvakultura i ribarstvo u Srbiji – stanje i potencijal

Akvakultura u Srbiji se najvećim delom realizuje u objektima akvakulture: pastrmskim i šaranskim ribnjacima. Ukupna površina pod šaranskim ribnjacima je oko 14 000 hektara, od čega je oko 20% van funkcije. Pod pastrmskim ribnjacima je oko 14 hektara od čega je oko 15 % van funkcije. U šaranskim ribnjacima se proizvodi šaran, beli i sivi tolstolobik, beli amur i grabljivice: som i smuđ. U pastrmskim ribnjacima se proizvodi kalifornijska (dužičasta) pastrmka. Na malom broju ribnjaka se proizvodi mlađ toplovodnih (deverika, linjak, zlatni karaš, šaran divljak) i hladnovodnih vrsta riba (potočna pastrmka, mladica, lipljan) za poribljavanje tekućih i stajaćih vodenih ekosistema. Ukupna proizvodnja u poslednjih dve godine se kreće u količini od oko 15 000 tona, od čega oko 2 000 tona kalifornijske pastrmke (od čega konzumne pastrmke oko 75%), i oko 13 000 tona toplovodnih vrsta riba (oko 11 000 tona šarana i oko 2 000 tona pratećih vrsta riba), od čega 70 do 75% konzumne ribe. Svi vodeni ekosistemi u Srbiji, sem objekata akvakulture (pastrmskih i šaranskih ribnjaka) i hidroakumulacija čije su prioritetne namene vodosnabdevanja se svrstavaju u ribolovne vode. Ukupna dužina svih potoka i reka je 65 980 km. Broj vrsta riba koje naseljavaju vodene ekosisteme u Srbiji je 89, svrstanih u 57 rodova i 20 familija. Od košljoriba koje naseljavaju vode u Srbiji 52 vrste se love rekreativnim i privrednim ribolovom. Privrednim ribolovom se bavi oko 260 privrednih ribara. Prosečan privredni ribar obavi oko 200 ribolovnih izlazaka na vodu u toku godine. Broj rekreativnih ribolovaca se u poslednjih desetak godina kreće od 58 000 (2001) do preko 100 000 (2002. godine). Prosečan rekreativni ribolovac godišnje obavi oko 50 ribolovnih izlazaka na vodu. Prema podacima RZS izlov iz reka u Srbiji je poslednjih godina između 2 000 i 3 000 tona. Potencijal razvoja akvakulture je baziran na mogućnostima unapređenja proizvodnje na postojećim ribnjacima, povećanju proizvodnih ribnjačkih površina, proizvodnji hrane za ribe, prerađivačkim kapacitetima za koje Srbija poseduje sirovine i potencijal za plasman preradjevina od ribe na tržište zemalja EU i drugih država. Potencial ribolova se može podeliti na onaj koji pružaju brdsko planinske tekućice i potencijal koji pružaju ravničarske reke. Potencijal brdsko planinskih tekućica baziran je na rekreativnom ribolovu, odnosno ribolovnom turizmu koji bi se razvio kao posledica želje da se dođe baš na izabrano područje. U cilju stvaranja atraktivnih ponuda, stvoren je osnov da se u narednom periodu poribljavanje obavlja sa mlađi čiji su roditelji iz istog toka, čime je stvoren preduslov za očuvanje autohtonih genotipova. Potencijal ravničarskih reka je znatno veći. Baziran je na rekreativnom i privrednom ribolovu. Potencijal koji pruža rekreativni ribolov je zasnovan na činjenici da je grad sa najvećim brojem stanovnika u Srbiji – Beograd, upravo lociran na obalama dve velike reke: Dunavu i Savi, ali i na činjenici da su gradovi Novi Sad, Šabac, Smederevo... locirani na obalama velikih reka, što svakako ukazuje na činjenicu da bi broj rekreativnih ribolovaca mogao biti višestruko veći. Veoma značajan potencijal je i u privrednom ribolovu koji bi uz unapređenje politike poribljavanja, gazdovanja i izlova ribe, ali i statusa privrednih ribara mogao predstavljati egzistenciju znatno većeg broja ljudi od sadašnjih

Possibilities of Improvement of Production Traits of the Carp (Cyprinus Carpio) by Selective Breeding

Selective breeding for growth rate in common carp (Cyprinus carpio L.) has not been actively pursued after some early unsuccessful selection experiments. Prerequisite for successful selective breeding is accurate and objective evaluation of genetic parameters used in the planning and implementation of selection methods. The aim of this work was to assess the possibilities of improving production traits (weight, length and height) that are related to the growth of carp, through selection. Estimated variation and heritabilities were significantly high for all examined characteristics. Based on the obtained results can be expected to improve growth rate of common carp through selective breeding

Stanje ribarstva u Srbiji

Fishery in Serbia comprises of aquaculture and fishery. Aquaculture in Serbia concerns fish culturing. For production of other aquatic animals, mainly ornamental plants and crayfish, only occasional interest and small scale production in aquarium type of units exists. Fish are produced in carp and trout fish farms (over 95%), to a smaller extent in cages, enclosed or partitioned natural or man made aquatic ecosystems. Aquaria fish culture is mainly low scale, with a small number of specialized breeders and one public aquarium (M a r k o v i ć i M i t r o v i ć T u t u n d ž i ć, 2003, 2005; M a r k o v i ć i P o l e k s i ć, 2007, M a r k o v i ć i sar., 2009). In Serbia freshwater species cultured are: common carp, white and gray bighead, wells, pike perch, rainbow trout and to a lesser degree Northern pike, tench, brown trout, beluga, Russian starlet. There is 13 500 – 14 000 ha of fish farms in Serbia, with 99.9% of carp farms and 0.1% of trout farms. The total fish production in recent years is between 10 000 and 15 000 tons with 70 to 75% of consumable fish. All three types of production systems are present: extensive, semi-intensive and intensive. Extensive production is sporadic and is present only at a few carp production units, mostly not economic for semi-intensive production due to remoteness from other production units or neglect. The principal type of production (75 – 80%) is semi-intensive production of cyprinids, with common carp as the main species. Common carp is present with more than 80% of the total production in warmwater fish farms. The traditional (old) type of feeding is slowly changing. Cereals are more often, at over 50% of production surfaces, totally of partially replaced by complete, peletted and even more extruded feed. This has resulted in an increase of production per surface unit in recent years. Intensive production systems in carp culture are less present, at a small number of earthen ponds with aeration systems, mainly for fish fry production, and in cages. However, rainbow trout, the only salmonid species cultured for consummation, is exclusively produced in intensive systems at trout farms in Serbia. The number of people involved full-time in fish production in Serbia is about 1100 and approximately 400 seasonal workers that are hired mainly prior to harvest. With the rising of standard and returning to traditional habits during religious fasting, as well as with a slow increase of “healthy food” supporters, fish consumption has a growing trend. However, although fish production is increasing in recent years, the country’s production and open-water capture fishery barely represent a quarter of the total needs of inhabitants. This results in increase of import, mainly marine and frizzed fish, but also freshwater fish. Open-water capture fishery is performed in Serbia’s fishing waters. They are represented by 66 000 km of water currents (rivers and streams), flood plains, backwaters, 50 lakes, 150 reservoir lakes and around 30 000 km of canal systems, hydromeliorative systems, as well as all other waters with fish. All fishing waters are divided into 6 fishing regions (Serbia – Vojvodina, Serbia – West, Serbia – South West, Srbia - South, Serbia – East, Serbia – Center) since year 2007. Sports fishing is obtainable at all regions but commercial fishery is aloud only at two regions (Serbia – Vojvodina, Serbia – west), and in rivers Tisa, Sava and Danube. Number of fisherman with purchased license in the last couple of years is between 50 000 and 100 000. Number of commercial fishermen is between 500 and 2000 in the last ten years. The amount of captured fish is between 2000 and 3000 tons in the few past years

Why rankings of biomedical image analysis competitions should be interpreted with care

International challenges have become the standard for validation of biomedical image analysis methods. Given their scientific impact, it is surprising that a critical analysis of common practices related to the organization of challenges has not yet been performed. In this paper, we present a comprehensive analysis of biomedical image analysis challenges conducted up to now. We demonstrate the importance of challenges and show that the lack of quality control has critical consequences. First, reproducibility and interpretation of the results is often hampered as only a fraction of relevant information is typically provided. Second, the rank of an algorithm is generally not robust to a number of variables such as the test data used for validation, the ranking scheme applied and the observers that make the reference annotations. To overcome these problems, we recommend best practice guidelines and define open research questions to be addressed in the future

Racial differences in systemic sclerosis disease presentation: a European Scleroderma Trials and Research group study

Objectives. Racial factors play a significant role in SSc. We evaluated differences in SSc presentations between white patients (WP), Asian patients (AP) and black patients (BP) and analysed the effects of geographical locations.Methods. SSc characteristics of patients from the EUSTAR cohort were cross-sectionally compared across racial groups using survival and multiple logistic regression analyses.Results. The study included 9162 WP, 341 AP and 181 BP. AP developed the first non-RP feature faster than WP but slower than BP. AP were less frequently anti-centromere (ACA; odds ratio (OR) = 0.4, P < 0.001) and more frequently anti-topoisomerase-I autoantibodies (ATA) positive (OR = 1.2, P = 0.068), while BP were less likely to be ACA and ATA positive than were WP [OR(ACA) = 0.3, P < 0.001; OR(ATA) = 0.5, P = 0.020]. AP had less often (OR = 0.7, P = 0.06) and BP more often (OR = 2.7, P < 0.001) diffuse skin involvement than had WP.AP and BP were more likely to have pulmonary hypertension [OR(AP) = 2.6, P < 0.001; OR(BP) = 2.7, P = 0.03 vs WP] and a reduced forced vital capacity [OR(AP) = 2.5, P < 0.001; OR(BP) = 2.4, P < 0.004] than were WP. AP more often had an impaired diffusing capacity of the lung than had BP and WP [OR(AP vs BP) = 1.9, P = 0.038; OR(AP vs WP) = 2.4, P < 0.001]. After RP onset, AP and BP had a higher hazard to die than had WP [hazard ratio (HR) (AP) = 1.6, P = 0.011; HR(BP) = 2.1, P < 0.001].Conclusion. Compared with WP, and mostly independent of geographical location, AP have a faster and earlier disease onset with high prevalences of ATA, pulmonary hypertension and forced vital capacity impairment and higher mortality. BP had the fastest disease onset, a high prevalence of diffuse skin involvement and nominally the highest mortality

Inventory of current EU paediatric vision and hearing screening programmes

Background: We examined the diversity in paediatric vision and hearing screening programmes in Europe. Methods: Themes relevant for comparison of screening programmes were derived from literature and used to compile three questionnaires on vision, hearing and public-health screening. Tests used, professions involved, age and frequency of testing seem to influence sensitivity, specificity and costs most. Questionnaires were sent to ophthalmologists, orthoptists, otolaryngologists and audiologists involved in paediatric screening in all EU fullmember, candidate and associate states. Answers were cross-checked. Results: Thirty-nine countries participated; 35 have a vision screening programme, 33 a nation-wide neonatal hearing screening programme. Visual acuity (VA) is measured in 35 countries, in 71% more than once. First measurement of VA varies from three to seven years of age, but is usually before the age of five. At age three and four picture charts, including Lea Hyvarinen are used most, in children over four Tumbling-E and Snellen. As first hearing screening test otoacoustic emission (OAE) is used most in healthy neonates, and auditory brainstem response (ABR) in premature newborns. The majority of hearing testing programmes are staged; children are referred after one to four abnormal tests. Vision screening is performed mostly by paediatricians, ophthalmologists or nurses. Funding is mostly by health insurance or state. Coverage was reported as >95% in half of countries, but reporting was often not first-hand. Conclusion: Largest differences were found in VA charts used (12), professions involved in vision screening (10), number of hearing screening tests before referral (1-4) and funding sources (8)

Knowledge about HPV Infection and the HPV Vaccine among Parents in Southeastern Serbia

Background and Objectives: The vaccine against human papilloma virus (HPV) infection is recommended, according to the Serbian National Immunization Program, for children and adolescents aged 9–19 years. Three doses are given keeping in mind the recommendation that the second dose should be administered at least one month after the first dose, and the third at least three months after the second dose. No children who participated in this first study received the third dose because they did not meet these criteria. The study explored parents’ knowledge about HPV infection and their awareness of the HPV vaccine. Materials and Methods: A cross-sectional questionnaire-based study was carried out in the city of Nis, in southeastern Serbia. According to the 2011 population census, the sample of children aged 9 to 19 was 850, and during the observed period, 631 children received the vaccine. A total of 615 fully completed questionnaires filled out by parents were included in the study. The study was carried out from 6 June 2022 to 7 October 2022. Multivariable logistic regression analysis was used. The odds ratio (OR) and 95% confidence intervals (CI) were calculated. The statistical significance was p < 0.05. Results: A total of 615 children were included in the study (499 were vaccinated with the first dose and 116 with the second). Out of 499 children vaccinated with the first dose, 398 (79.6%) were girls, which is significantly higher than the rate for boys (101). The independent variable sex was statistically significant at the level of p = 0.84, OR = 2.664 (95% CI from 0.879 to 7.954). Boys are 164% less likely to be vaccinated with the HPV vaccine than girls. We determined that the independent variable place of residence was significant at the level of p = 0.041, (OR = 3.809, 95% CI from 1.702 to 8.525). Based on these findings, we determined that parents who came from rural areas were 82% less likely to know about HPV infection and HPV vaccination. Children under 15 years of age were significantly more vaccinated than those ≥15 years (OR = 3.698, 95% CI from 1.354 to 12.598). The independent variable parental education was significant at the level of OR = 0.494, 95% CI from 0.301 to 0.791. Parents who had medical education showed significantly higher awareness about the infection caused by HPV and about the HPV vaccine (p = 0.004) than parents with no medical education. The possibility that a parent would decide to vaccinate a child significantly increased upon a pediatrician’s recommendation, p = 0.000 with OR = 0.250 (95% CI from 0.127 to 0.707). Health insurance coverage of HPV vaccination for children aged 9–19 years significantly increased the probability of a positive parental decision to vaccinate a child, p = 0.001 with OR = 3.034 (95% CI from 1.063 to 8.662). Conclusion: We identified several significant factors that were important for HPV vaccination such as: children under 15 years, female sex, urban place of residence, medical education of parents, pediatrician’s recommendation of the HPV vaccination, and HPV vaccination free of charge. Health education and the promotion of HPV vaccination as well as healthy sexual behavior are important factors in the preservation and improvement of the health of the whole population

How to exploit weaknesses in biomedical challenge design and organization

\u3cp\u3eSince the first MICCAI grand challenge organized in 2007 in Brisbane, challenges have become an integral part of MICCAI conferences. In the meantime, challenge datasets have become widely recognized as international benchmarking datasets and thus have a great influence on the research community and individual careers. In this paper, we show several ways in which weaknesses related to current challenge design and organization can potentially be exploited. Our experimental analysis, based on MICCAI segmentation challenges organized in 2015, demonstrates that both challenge organizers and participants can potentially undertake measures to substantially tune rankings. To overcome these problems we present best practice recommendations for improving challenge design and organization.\u3c/p\u3