Strength Analysis of the Marine Weapon’s Construction

Due to the modernization of warships, it was necessary to carry out strength calculations for the newly assembled devices, for which there were no detailed technical requirements. The authors try to present and harmonize the requirements for naval military structures. The lack of experimental verification of newly built systems was indicated. Therefore the finite element method was used to determine the durability of the critical design elements. There is no explicit reference load in the literature, so the authors present a general solution to one of the worst cases. The work presents the cannon structure elements exposed to damage during the underwater explosion load, using the proposed methodology. The proposed method is sufficient to calculate individual ship cases. However, in the case of hull strength analysis, more complex algorithms should be used

The influence of severe mitral regurgitation on major adverse cardiac and cerebrovascular events after myocardial infarction in 1-year follow-up: Data from PL-ACS registry

Background: Mitral regurgitation (MR) is frequently observed in patients with myocardial infarction (MI). However, the incidence of severe MR in contemporary population is unknown. Aims: The study evaluates the prevalence and prognostic impact of severe MR in contemporary population of patients with ST-segment elevation myocardial infarction (STEMI) and non-ST-segment elevation myocardial infarction (NSTEMI). Methods: The study group consists of 8062 patients enrolled in the Polish Registry of Acute Coronary Syndromes over the years 2017‒2019. Only the patients with full echocardiography performed during the index hospitalization were eligible. Primary composite outcome was 12-month major adverse cardiac and cerebrovascular events (MACCE) (death, non-fatal MI, stroke and heart failure [HF] hospitalization) compared between patients with and without severe MR. Results: 5561 NSTEMI patients and 2501 STEMI patients were enrolled into the study. Severe MR occurred in 66 (1.19%) NSTEMI patients and 30 (1.19%) STEMI patients. Multivariable regression models revealed that severe MR is an independent risk factor of all-cause death in 12-month observation (odds ratio [OR], 1.839; 95% confidence interval [CI], 1.012‒3.343; P = 0.046) in all MI patients. Patients with NSTEMI and severe MR had higher mortality (22.7% vs. 7.1%), HF rehospitalization rate (39.4% vs. 12.9%) and MACCE occurrence (54.5% vs. 29.3%). Severe MR was associated with higher mortality (20% vs. 6%) and higher HF rehospitalization (30% vs. 9.8%), stroke (10% vs. 0.8%) and MACCE rates (50% vs. 23.1%) in STEMI patients. Conclusions: Severe MR is associated with higher mortality and MACCE occurrence in patients with MI in 12-month follow-up. Severe MR is an independent risk factor of all-cause death

Safety and efficacy of embolic protection devices in saphenous vein graft interventions : a propensity score analysis-multicenter SVG PCI PROTECTA study

Background: Evidence concerning the efficacy of the embolic protection devices (EPDs) in saphenous vein graft (SVG) percutaneous coronary intervention (PCI) is sparse. The study was designed to compare major cardiovascular events of all-comer population of SVG PCI with and without EPDs at one year of follow-up. Methods and results: A multi-center registry comparing PCI with and without EPDs in consecutive patients undergoing PCI of SVG. The group comprised 792 patients, among which 266 (33.6%) had myocardial infarction (MI). The primary composite endpoint was major adverse cardiac and cerebrovascular event (MACCE) defined as death, MI, target vessel revascularization (TVR), and stroke assessed at one year. After propensity score analysis, there were no differences in MACCE (21.9% vs. 23.9%; HR 0.91, 95% CI 0.57–1.45, p = 0.681, respectively) nor in secondary endpoints of death, MI, TVR, target lesion revascularization (TLR) and stroke at one year in EPDs PCI group vs. no-EPDs PCI group. Similarly, there were no differences between groups in the study endpoints at 30 days follow-up. Conclusions: There were no clinical benefit for routine use of EPDs during SVG PCI in short and long-term follow-up. Further studies are warranted to explore the effect of individual types of EPDs on clinical outcomes

Przezcewnikowa implantacja zastawki aortalnej w leczeniu dysfunkcyjnych bioprotez chirurgicznych i przezcewnikowych. Opinia ekspertów Asocjacji Interwencji Sercowo-Naczyniowych Polskiego Towarzystwa Kardiologicznego

Ponad 15-letnie doświadczenie i wyniki dużych badań obserwacyjnych, na podstawie których tworzone są wytyczne, wskazują na bezpieczeństwo i skuteczność zabiegów przezcewnikowej implantacji „zastawki w zastawkę” (ViV-TAVI, valve-in-valve transcatheter aortic valve implantation), zmniejszając tym samym potrzebę reoperacji u pacjentów wysokiego ryzyka. Oczekuje się, że liczba zabiegów ViV-TAVI w Polsce, szacowana na około 2% wszystkich przezcewnikowej implantacji zastawki aortalnej w 2020 roku, będzie rosła. Niniejszy dokument ma na celu przegląd aspektów proceduralnych ViV-TAVI, w tym odpowiednich metod planowania przedzabiegowego, sposobów optymalizacji wyników hemodynamicznych i ograniczania ryzyka okluzji tętnic wieńcowych. Dokument zawiera również wstępny przegląd wskazań i wytycznych dotyczących ponownego zabiegu TAVI (re-do TAVI) u pacjentów ze zdegenerowanymi zastawkami przezcewnikowymi

Wyrazy n-fonemowe i n-sylabowe w mowie dorosłych adresowanej do niemowląt

N-phoneme and N-syllable expressions in adult speech directed to infants Studies devoted to phonostatic research have made clear that there is a correlation between the frequency of words of a certain phoneme and syllable length and their adherence to certain stylistic variations of Polish. The fact of the occurrence of a higher number of shorter or longer words depending on the type of analysed expressions was noticed by linguists at the beginning of the 20th century, although most of these opinions were not yet supported by a proper quantity of data. Such data began to published in the 1970s. My article presents results concerning the frequency of n-phoneme and n-syllable words in a particular, simplified register of infant-directed speech (IDS). A comparison of the frequency of the occurrence of words of a certain phoneme and syllable length in IDS with the data obtained from other speech samples, among them the Polish of pre-schoolers and contemporary Polish, allows one to state that the length of words may be one of the most important criteria evidencing the “difference” of infant-directed speech. The analysed language material (cassette recording) came from 102 child-carers (mothers, fathers and grandmothers). It was listened to, phonologically transcribed and entered into a computer memory by one person. All of the analysed text consisted of 74,534 words (308,918 phonemes)