The role of physical activity in prevention and treatment of peripheral vascular disorders

Peripheral vascular diseases constitute one of the most significant medical and social problems. Physiotherapy plays an important role among and in addition to various treatment modalities. Physiotherapy for vascular applied in vessel disease treatment primaliry consists of resonable and regular exercises and activities, and selected physical procedures. The review paper presents current data concerning the most commonly applied exercises and physical procedures in selected peripheral vascular diseases

Compression therapy in venous diseases : physical assumptions and clinical effects

Compression therapy (CT) is an established treatment method in chronic venous disease. Despite years of clinical experience, choosing the optimum compression therapy, including grade and pressure distribution, which determine the efficacy of treatment poses a challenge. The paper discusses CT physical assumptions (stiffness, elasticity, static and dynamic stiffness indices), clinical effects and contraindications to CT

Decreased oxidative stress in male patients with active phase ankylosing spondylitis who underwent whole-body cryotherapy in closed cryochamber

The aim of the study was to estimate the impact of whole body cryotherapy (WBC) on oxidative stress when performed in a closed cryochamber on patients with ankylosing spondylitis (AS). Material and methods. The effect of ten WBC procedures lasting 3 minutes a day with a subsequent 60-minute session kinesiotherapy on oxidative stress in male AS patients (WBC group n = 16) was investigated. To assess the disease activity, the Bath Ankylosing Spondylitis Diseases Activity Index (BASDAI) and Bath Ankylosing Spondylitis Functional Index (BASFI) were calculated. The WBC group was compared to the kinesiotherapy only (KT; n = 16) group. The routine parameters of oxidative stress (antioxidant enzymatic and nonenzymatic antioxidant status, lipid peroxidation products, total oxidative status (TOS), and oxidative stress index (OSI)) were estimated one day before the beginning and one day after the completion of the research program. Results. After the completion of the treatment in the WBC group, a significant decrease of oxidative stress markers (TOS and OSI) and a significant increase of total antioxidant status were observed. The erythrocyte activity of glutathione peroxidase, glutathione reductase decreased significantly in both groups, but the differences of activity of that enzymes prior to post treatment values (Δ) in the KT group were significantly higher as compared to the WBC group. The activity of erythrocyte catalase and plasma ZnCu isoenzyme of superoxide dismutase showed a decreased tendency; erythrocyte total superoxide dismutase activity showed an increased tendency in the WBC group after the completion of the treatment. The BASDAI and BASFI decreased significantly in both groups, but the differences of value indexes prior to post treatment (Δ) were significantly higher in the WBC than KT group. Conclusion. WBC performed in a closed cryochamber decreases oxidative stress and improves BASDAI and BASFI indexes in male patients during the active phase of ankylosing spondylitis

Compression therapy in venous diseases : current forms of compression materials and techniques

Compression therapy (CT) is an established treatment method in chronic venous disease (CVD). The paper presents information on different CT forms with indications and contraindications based on expert consensuses from recent years. A high prevalence of CVD implies continuous development of compression materials, systems and techniques as well as measurement methods. The article aims at reviewing available literature on the development of compression therapy techniques

Different expression of cyclooxygenase-2 (COX-2) in selected nonmelanocytic human cutaneous lesions

The aim of our study was to elucidate the possible involvement of COX-2 in the development and/or progression of nonmelanocytic skin lesions. To evaluate the usefulness of that enzyme as a potential molecular marker, we examined the intensity and spatial distribution of COX-2 expression in selected types of such tumors using the same immunohistochemical procedure as in our earlier studies of melanocytic cancers. We examined 20 benign epithelial lesions, 11 precancerous lesions, 21 basal cell carcinomas (BCC), 14 squamous cell carcinomas (SCC) and eight fibromas. The levels of COX-2 expression detected in benign lesions and in normal skin were comparable. Elevated expression of this protein may play a role in the development of SCC, as indicated by strong immunostaining both in SCCs and precancerous lesions. Significantly stronger staining in SCCs compared to BCCs may indicate a role of COX-2 in cancer malignancy and serve as an indicator useful for differential diagnostics of the two types of cancer. Strong staining in all skin layers of SCC may help in detecting cancer cells infiltrating surrounding skin layers. (Folia Histochemica et Cytobiologica 2011; Vol. 49, No. 3, pp. 381–388

Whole-Body Cryotherapy Decreases the Levels of Inflammatory, Oxidative Stress, and Atherosclerosis Plaque Markers in Male Patients with Active-Phase Ankylosing Spondylitis in the Absence of Classical Cardiovascular Risk Factors

Objective. The aim of the study was to estimate the impact of whole-body cryotherapy (WBC) on cardiovascular risk factors in patients with ankylosing spondylitis (AS). Material and Methods. We investigated the effect of WBC with subsequent kinesiotherapy on markers of inflammation, oxidative stress, lipid profile, and atherosclerosis plaque in male AS patients (WBC group). To assess the disease activity, the BASDAI and BASFI were also calculated. The results from the WBC group were compared with results from the kinesiotherapy (KT) group. Results. The results showed that in the WBC group, the plasma hsCRP level decreased without change to the IL-6 level. The ICAM-1 level showed a decreasing tendency. The CER concentration, as well as the BASDAI and BASFI, decreased in both groups, but the index changes of disease activity were higher in the WBC than KT patients. Additionally, in the WBC group, we observed a decrease in oxidative stress markers, changes in the activity of some antioxidant enzymes and nonenzymatic antioxidant parameters. In both groups, the total cholesterol and LDL cholesterol, triglycerides, sCD40L, PAPP-A, and PLGF levels decreased, but the parameter changes were higher in the WBC group. Conclusion. WBC appears to be a useful method of atherosclerosis prevention in AS patients

Thermal imaging application in chronic venous disease : pilot study

Thermal imaging was used for the estimation of lower-limb primary chronic venous diseases connected with an insufficiency of superficial veins. The current study was performed by means of a Thermovision A40 camera. The curves of the chosen regions of interest were performed in a research room with a stabilized temperature. Curves of the lower extremities showed that the patients suffered from a venous insufficiency characterized by a higher skin temperature connected with pathological changes in the veins. Changes seen in the lower extremities skin thermal map may be associated with blood stasis, inflammatory states and swelling. The differences in temperature distribution are due to a correlation between the medical diagnosis and the parameters obtained from duplex scanning. The results of the thermal imaging showed differences between patients’ health may suggest that a thermovision of lower extremities venous diseases can be very useful in medical diagnosis. The correlation was obtained from temperature parameters and duplex scanning. The parameters may suggest that thermovision diagnostics may be useful as a complementary method in the diagnosis of chronic venous diseases in the lower extremities

Does local cryotherapy improve thermal diagnosis similar to whole-body cryotherapy in spinal diseases?

Thermal imaging has been used for patients with spinal diseases who were qualified by their physicians for whole-body treatment or local cryotherapy. The experimental groups of patients consisted of 20 males aged 51.6 ± 9.0 (12 treated by whole-body cryotherapy and 8 by local cryotherapy). The distribution of the skin surface temperature was monitored by using a Thermovision Camera E60 before and immediately after body cooling. The chosen spinal region (Th5/Th6–L5/S1) was taken into consideration for all of the research groups. An essential drop in skin temperature and a better differentiation of the body surface temperatures (leading to an increase in the diagnostic value of thermography) was observed after both methods of cold impact. In order to estimate the usefulness of thermovision used after body cooling, the quantitative parameters including temperature contrast—the difference between the maximum and minimum temperatures before and after cold impact and relative contrast ratio (related to the average temperature of the selected area of interest, before and after cooling, respectively)—were compared for both kinds of medical treatment. The statistical analysis proved that significant differences between the parameters obtained before and after body cooling in the case that patients treated by local and whole-body cryotherapy are similar. However, local therapy is cheaper and easy for application while whole-body therapy can give more information about the state of soft tissues for the whole back

How to use thermal imaging in venous insufficiency?

This paper is intended to provide studies performer on usefulness of thermal imaging for the insufficiency of superficial veins in the lower limbs. The results are a continuation of the previous research and show a new way of analysis and better correlation between standard methods of parameters like duplex ultrasonography and parameters derived from thermal imaging. In particular promised seems to be using the mean whole limb temperaturę of healthy volunteers at a proper age as a threshold to count the isotherm area, and in isotherm analysis should be taken for the whole lower limb—the sum of thermal images from anterior and posterior views (Method II). The study was performed by the use of a Thermovision E60 camera by Flir Systems. All studies (duplex ultrasonography as well as thermal imaging) were performed in a research room with a stabilized temperature on two groups of patients, a group of healthy people and patients suffering from chronic venous disease. During the study, the correlation parameters were obtained with ultrasound and thermal parameters. The results showed that temperaturę changes observed in the lower extremities of the thermal skin map are associated with a healthy state of blood supply which might be connected with blood stasis, inflammatory states and swelling that occurs in the soft tissues. We found the mean and higher correlations between thermal and ultrasound parameters, for example, a good positive correlation (r = 0.63) between the thermal range to the total limb length radio and the range of reflux was obtained. The correlation between thermal imaging parameters and duplex ultrasound parameters may show that thermovision is an extremely promising method, and it can be useful in the screening of diagnosis of superficial vein insufficiency

Cardiovascular complications in secondary hyperparathyroidism — specific changes, prevention and treatment

Częstość występowania przewlekłej choroby nerek (PChN) jest wysoka i stale wzrasta. Wiąże się to ze zmianami demograficznymi i epidemią chorób cywilizacyjnych takich jak cukrzyca, nadciśnienie tętnicze, otyłość. W miarę utraty czynnego miąższu nerek narasta ilość powikłań towarzyszących tej chorobie. Jednym z najczęstszych jest rozwój wtórnej nadczynności przytarczyc, która stymuluje pojawianie się powikłań sercowo-naczyniowych. W pracy przedstawiono czynniki ryzyka powstania zmian naczyniowych we wtórnej nadczynności przytarczyc, najczęstszego rodzaju histologicznych układu sercowo-naczyniowego, oraz zasady profilaktyki i leczenia wtórnej nadczynności przytarczyc.The incidence of chronic kidney diseases (CKD) is high and still growing. It is connected with demographic changes, as well as epidemics of civilization-related diseases, such as diabetes, arterial hypertension, obesity. As the active renal parenchyma is lost, the amount of complications accompanying the disease increases. One of the most frequent complications is the development of secondary hyperparathyroidism, which stimulates the occurrence of cardiovascular complications. The authors of the study presented risk factors for vascular lesions in secondary hyperparathyroidism, the most frequent type of histological lesions in the cardiovascular system, as well as the principles for prevention and treatment of secondary hyperparathyroidism