2 research outputs found
Cardiovascular Disease and Hepatitis C Virus Infection An Irrelevant Statement or a Hot Relationship?
Hepatitis C virus (HCV) is well known for being the leading cause of
hepatocellular carcinoma and cirrhosis, contributing to a devastating
array of metabolic dysfunctions associated with hepatic failure.
However, the cardiac manifestations of HCV and chronic hepatitis C (CHC)
are being explored, thus illuminating the connection between HCV
infection and cardiac disease. Although not all studies agree, the
evidence in favor of CHC promoting major risk factors for cardiovascular
disease such as hypertension, insulin resistance, diabetes mellitus, and
atherosclerosis is compelling. Similarly, properly warranted attention
is being guided towards CHC as an independent risk factor for the
development of atherosclerotic heart disease and cardiomyopathy. This
review provides a synopsis on the relationship between (HCV) infection
and cardiac disease, emphasizing on some of the key possible mechanisms
and population derived data