Application of an Intuitive, Glove-type Remote Control with Haptic Feedback to Quadcopters

Although remote controllers for drones, based upon a classic two-joystick architecture, are unwieldy, they still see widespread use. As a replacement, we propose a remote control with a glove-based architecture that utilizes haptic feedback from the quadcopter. The proposed controller should be far more intuitive, making drone flight easier and more intuitive. Additionally, since the pilot will have one hand free, he or she can use maps, electronics, and other aids much more straightforwardly than with a two-handed controller. While our technology is designed for drones, it also could see further usage in a wide variety of civilian and military applications, from entertainment to industry. This glove-based architecture with haptic feedback might well become a staple of the future

Te Whāriki Kiokio - Te Ruru light festival 2019

This interactive installation consists of 3 digital tukutuku panels which are rear-projected onto a screen. The viewer is presented with 3 foot pates, each with a unique tukutuku symbol. When stepped on, it activates an animated digital tukutuku design. At the same time, it activates a sound associated with the specific panel designs. These sound are either recordings of Māori instruments (purerehua, kōauau, etc.), Māori speech (whaikōrero) or Māori chants (waiata). One can be activated at one time and as soon as another metallic symbol is pressed the current panel turns off and the new one is activated. This work is an adaption of an earlier work shown at Wellington LUX Festival 2017, and the Bruce Mason Centre in 2018. Co-designer Stacey Tangaere: 'Te Whāriki Kiokio came from a passion to see traditional Māori art fused with a modern art form. As I went on this journey I visited Pakowhai Marae and quickly became interested in the tukutuku panels. These panels quickly caught my attention as they have always been there but they are often ignored in the space. So much hard work and meaning has gone into every piece of flax yet to many they are almost viewed as wallpaper. Traditionally Māori learnt with their hands, through touching and feeling.' The idea behind this interactive installation is that as you trigger the panels you will not only feel moved by the experience but you will also leave educated. The audio is used to enhance the experience of Te Whāriki Kiokio with unique sounds developed to tautoko (support) the meaning of each tukutuku

Riparian vegetation patterns and links with surface waters in the boreal forest

Riparian areas in the Canadian boreal forest represent the transition zone between terrestrial and aquatic ecosystems. Factors that influence riparian vegetation communities and the associated interactions with boreal streams were reviewed. Regional and local drivers (e.g., climate and site hydrology) that affect upland boreal vegetation also operate in riparian areas. However, the proximity of riparian areas to the stream channel not only modifies some of these drivers, but it means that the stream itself becomes a driver of riparian vegetation dynamics. For example, hydrological disturbances like flooding and ice scour affect soil texture and alter successional pathways, sometimes completely denuding streambanks of vegetation. Even in riparian areas unaffected by such catastrophic disturbances, saturated soil conditions can influence riparian forest composition and nutrient cycling

ChemSIM: Visualizing Chemical Equilibrium Through a Java-Based Program

Undergraduate Theoretical Proposa

Sustainability of evidence-based healthcare: Research agenda, methodological advances, and infrastructure support

BACKGROUND: Little is known about how well or under what conditions health innovations are sustained and their gains maintained once they are put into practice. Implementation science typically focuses on uptake by early adopters of one healthcare innovation at a time. The later-stage challenges of scaling up and sustaining evidence-supported interventions receive too little attention. This project identifies the challenges associated with sustainability research and generates recommendations for accelerating and strengthening this work. METHODS: A multi-method, multi-stage approach, was used: (1) identifying and recruiting experts in sustainability as participants, (2) conducting research on sustainability using concept mapping, (3) action planning during an intensive working conference of sustainability experts to expand the concept mapping quantitative results, and (4) consolidating results into a set of recommendations for research, methodological advances, and infrastructure building to advance understanding of sustainability. Participants comprised researchers, funders, and leaders in health, mental health, and public health with shared interest in the sustainability of evidence-based health care. RESULTS: Prompted to identify important issues for sustainability research, participants generated 91 distinct statements, for which a concept mapping process produced 11 conceptually distinct clusters. During the conference, participants built upon the concept mapping clusters to generate recommendations for sustainability research. The recommendations fell into three domains: (1) pursue high priority research questions as a unified agenda on sustainability; (2) advance methods for sustainability research; (3) advance infrastructure to support sustainability research. CONCLUSIONS: Implementation science needs to pursue later-stage translation research questions required for population impact. Priorities include conceptual consistency and operational clarity for measuring sustainability, developing evidence about the value of sustaining interventions over time, identifying correlates of sustainability along with strategies for sustaining evidence-supported interventions, advancing the theoretical base and research designs for sustainability research, and advancing the workforce capacity, research culture, and funding mechanisms for this important work

Acute kidney injury in patients undergoing elective primary lower limb arthroplasty

Acknowledgements The authors would like to thank Abhi Punit for his contributions in data collection towards the above article Funding No funds, grants or other support was received.Open access via springer agreementPeer reviewedPublisher PD

Experience and response to a randomised controlled trial of extended-release injectable buprenorphine versus sublingual tablet buprenorphine and oral liquid methadone for opioid use disorder:protocol for a mixed-methods evaluation

INTRODUCTION: Opioid use disorder (OUD) is a debilitating and persistent disorder. The standard-of-care treatment is daily maintenance dosing of sublingual buprenorphine (BUP-SL) or oral methadone (MET). Monthly, extended-release, subcutaneous injectable buprenorphine (BUP-XR) has been developed to enhance treatment effectiveness. This study aims to investigate the experiences of participants who have been offered BUP-XR (evaluation 1), health-related quality-of-life among participants who have opted to receive BUP-XR longer term (evaluation 2) and the experiences of participants allocated to receive BUP-XR or BUP-SL or MET with the offer of adjunctive personalised psychosocial intervention (evaluation 3). METHODS AND ANALYSIS: Three qualitative–quantitative (mixed-methods) evaluations embedded in a five-centre, head-to-head, randomised controlled trial of BUP-XR versus BUP-SL and MET in the UK. Evaluation 1 is a four-centre interview anchored on an OUD-related topic guide and conducted after the 24-week trial endpoint. Evaluation 2 is a two-centre interview anchored on medications for opioid use disorder-specific quality-of-life topic guide conducted among participants after 12–24 months. Evaluation 3: single-centre interview after the 24-week trial endpoint. All evaluations include selected trial clinical measures, with evaluation 2 incorporating additional questionnaires. Target participant recruitment for evaluations 1 and 2 is 15 participants per centre (n=60 and n=30, respectively). Recruitment for evaluation 3 is 15 participants per treatment arm (n=30). Each evaluation will be underpinned by theory, drawing on constructs from the behavioural model for health service use or the health-related quality-of-life model. Qualitative data analysis will be by iterative categorisation. ETHICS AND DISSEMINATION: Study protocol, consent materials and questionnaires were approved by the London-Brighton and Sussex research ethics committee (reference: 19/LO/0483) and the Health Research Authority (IRAS project number 255522). Participants will be provided with information sheets and informed written consent will be obtained for each evaluation. Study findings will be disseminated through peer-reviewed scientific journals. TRIAL REGISTRATION NUMBER: 2018-004460-63

The production of Necator americanus larvae for use in experimental human infection

Background: Although there is unprecedented interest in experimental human hookworm infection, details of hookworm manufacture and characterisation have been sparsely reported. In this report, we detail the production and characterisation of Necator americanus larvae for use in a recently published clinical trial. Methods: Faeces was obtained from an experimentally infected donor. Faecal hookworm DNA was determined by quantitative PCR. Paired samples were incubated in either sterile water or sterile water mixed with antimicrobials (amphotericin and gentamicin). Coproculture was performed by modified Harada-Mori method. The harvested larvae were then processed in either sterile water or antiseptic solution. Larval yield was then calculated (larvae per gram), larval viability was determined by thermally induced motility assay and microbial burden was determined at the day of harvest, at 48 h and at 7 days. Results: Twenty-eight faecal cultures were performed over 16 months. The faecal hookworm DNA content was variable over this time. There was no association of larval yield with faecal hookworm DNA content. Pre-treatment of faeces with antimicrobials did not influence larval yield. Larval motility was 85.3% (95% CI 79.3–91.3%). Incubation of larvae in antiseptics did not reduce viability at 14 days with a marginal mean of 68.6% (95% CI 59.1–78.1%) washed in water vs. 63.3% (95% CI 53.8 – 72.9%) when incubated in betadine (p = 0.38). Larvae washed in sterile water did not meet microbial bioburden criteria. Incubation in antiseptic resulted in acceptable microbial bioburden at 48 h but not at 7 days. Although the addition of gentamicin did reduce the microbial bio-burden acceptable levels, it was found to significantly lower larval motility at 7 days compared to incubation in sterile water and motility at 7 days 37.8% (95% CI 4.7–70.9%) vs. 67.3% (95% CI 35.2–99.3%, p < 0.001), respectively. Conclusions: Despite standardised culture methodologies and the use of a single donor, larval yield varied considerably between batches and had no association with faecal hookworm DNA. Larval viability decreases over time and the age of larvae at time of use are likely to be important. Microbial bioburden maybe temporarily reduced by incubation in antiseptics and has little effect on viability. Incubation of larvae in gentamicin is effective at reducing microbial bioburden but is deleterious to larval viability