Deep neck infection complicating lymphadenitis caused by Streptococcus intermedius in an immunocompetent child

BACKGROUND: Streptococcus intermedius belongs to the Streptococcus anginosus group. It is part of the normal flora of the human mouth, but it can be etiologically associated with deep-site infections. CASE PRESENTATION: We present a case of deep neck infection complicating Streptococcus intermedius lymphadenitis, which developed in an immunocompetent 14-year-old boy with a history of recent dental work. The infection was ultimately eradicated by a combined medical and surgical approach. CONCLUSION: Our report suggests that combined medical and surgical therapy is essential for the complete resolution of deep infections caused by Streptococcus intermedius. Molecular biological techniques can be useful in guiding the diagnostic investigation and providing insight into the possibility of occult abscesses, which are particularly common with Streptococcus intermedius infections

Chronic interstitial lung diseases in pediatrics

Interstitial lung disease (ILD) in children includes a large spectrum of rare respiratory disorders that are mostly associated with high morbidity and mortality. These conditions are characterized by inflammatory and fibrotic changes that affect alveolar walls. Typical features of ILD include dyspnea, diffuse infiltrates on chest radiographs, and abnormal pulmonary function tests with restrictive ventilatory defect and final impaired gas exchanges. Diagnosis needs to be structured with a clinical evaluation requiring a careful history paying attention to exposures and systemic diseases, but is focused on the histopathologic evaluation of lungs

Sindromi febbrili periodiche

In modo sintetico sono descritti gli elementi clinici a supporto della diagnosi delle più comuni sindromi autoinfiammatorie ereditarie dell'infanzia

Lung transplantation in the pediatric age

Lung transplantation has matured into an accepted therapeutic alternative for children with end-stage lung disease: this review depicts the clinical use of this technique in the pediatric age

Pediatric use of thoracic high-resolution CT in the diagnosis of idiopathic pulmonary fibrosis. A case report

La descrizione di questo caso sottolinea l'utilit\ue0 della tomografia computerizzata nella gestione della fibrosi polmonare idiopatica, malattia rara e grave se ad esordio in et\ue0 pediatrica

Limp due to renal tubular dysfunction as diagnostic clue for hereditary tyrosinemia type 1.

A child with muscular weakness and limp is reported as an example of how heterogeneous might be the clinical presentation of tyrosinemia type 1

Longitudinal study of microvascular involvement by nailfold capillaroscopy in children with Henoch-Schönlein purpura

The aim of this study is to describe by video-nailfold capillaroscopy the microvascular involvement and capillary changes in children with Henoch-Schönlein purpura (HSp) and to establish a possible correlation with clinical outcome. Thirty-one patients underwent capillaroscopic evaluation through a videomicroscope during the acute phase and after 6 months. Twenty sex/age-matched controls were also examined. All capillaroscopic variables were statistically examined in combination with laboratoristic/clinical data. Architectural and morphological changes recorded during the acute phase were statistically significant in comparison to the controls (p < 0.01). At the follow-up, oedema was still observed in all patients, whereas, morphological changes only in two. There was a no significant correlation between capillaroscopy changes, laboratoristic/clinical data, and outcome. Video-nailfold capillaroscopy can be a simple tool to evaluate microvascular abnormalities in the acute phase of HSp, and the persistence of oedema could suggest an incomplete disease resolution at a microvascular level

A new preparation of specific anti-varicella-zoster immunoglobulin. Clinical evaluation in immunodepressed subjects

A new preparation of specific anti-varicella-zoster immunoglobulin. Clinical evaluation in immunodepressed subject

Functional and structural improvement of knee arthropathy in CINCA syndrome under treatment with recombinant human interleukin-1 receptor antagonist (anakinra).

A child with CINCA syndrome has received a biologic treatment with anakinra, showing a paramount response at both clinical and laboratory level. In particular, the response of the skeletal signs of this disease is widely dicussed