5,399 research outputs found
Facilitating Coherence across Qualitative Research Papers
Bringing the various elements of qualitative research papers into coherent textual patterns presents challenges for authors and editors alike. Although individual sections such as presentation of the problem, review of the literature, methodology, results, and discussion may each be constructed in a sound logical and structural sense, the alignment of these parts into a coherent mosaic may be lacking in many qualitative research manuscripts. In this paper, four editors of The Qualitative Report present how they collaborate with authors to facilitate improvement papersâ coherence in such areas as co-relating title, abstract, and the paper proper; coordinating the method presented with method employed; and calibrating the exuberance of implications with the essence of the findings. The editors share exercises, templates, and exemplary articles they use to help mentor authors to create coherent texts
Immunolocalization of basic fibroblast growth factor receptors in internal thoracic artery and saphenous vein grafts
Guidance of ganciclovir therapy with pp65 antigenemia in cytomegalovirus-free recipients of livers from seropositive donors
Facilitating Coherence across Qualitative Research Papers
Bringing the various elements of qualitative research papers into coherent textual patterns presents challenges for authors and editors alike. Although individual sections such as presentation of the problem, review of the literature, methodology, results, and discussion may each be constructed in a sound logical and structural sense, the alignment of these parts into a coherent mosaic may be lacking in many qualitative research manuscripts. In this paper, four editors of The Qualitative Report present how they collaborate with authors to facilitate improvement papers\u27 coherence in such areas as co-relating title, abstract, and the paper proper; coordinating the method presented with method employed; and calibrating the exuberance of implications with the essence of the findings. The editors share exercises, templates, and exemplary articles they use to help mentor authors to create coherent texts
Congestion delays at hub airports
Cover titleJune 1986Includes bibliographical references (p. 146)A deterministic model was developed to study the effects of inefficient scheduling on flight delays at hub airports. The model bases the delay calculation on published schedule data and on user-defined airport capacities. Data from the Official Airline Guide of May, 1977 and May, 1985 was used for the analysis. Twelve large airports were studied in the hopes of finding a correlation between airport delay due to congestion and hubs. Data for both time periods was analyzed for the twelve airports in order to find historical trends in the growth of hubbing. Among the airports studied, those that were hubs had significantly more delays due to inefficient scheduling than the non-hubs, even for an equivalent number of operations. Also, these relative inefficiencies were shown to exist from hub to hub. Delays at hubs of similar size differed by up to 200 percent
Lonesome For You
Man in suit sitting in chair by fireplace looking at photograph of woman on sill of fireplacehttps://scholarsjunction.msstate.edu/cht-sheet-music/7458/thumbnail.jp
Loss of CNTNAP2 Alters Human Cortical Excitatory Neuron Differentiation and Neural Network Development
BACKGROUND: Loss-of-function mutations in the contactin-associated protein-like 2 (CNTNAP2) gene are causal for neurodevelopmental disorders, including autism, schizophrenia, epilepsy and intellectual disability. CNTNAP2 encodes CASPR2, a single-pass transmembrane protein that belongs to the neurexin family of cell adhesion molecules. These proteins have a variety of functions in developing neurons, including connecting presynaptic and postsynaptic neurons, and mediating signalling across the synapse. METHODS: To study the effect of loss of CNTNAP2 function on human cerebral cortex development, and how this contributes to the pathogenesis of neurodevelopmental disorders, we generated human iPSCs from one neurotypical control donor null for full-length CNTNAP2, modelling cortical development from neurogenesis through to neural network formation in vitro. RESULTS: CNTNAP2 is particularly highly expressed in the first two populations of early-born excitatory cortical neurons, and loss of CNTNAP2 shifted the relative proportions of these two neuronal types. Live imaging of excitatory neuronal growth showed that loss of CNTNAP2 reduced neurite branching and overall neuronal complexity. At the network level, developing cortical excitatory networks null for CNTNAP2 had complex changes in activity compared to isogenic controls: an initial period of relatively reduced activity compared with isogenic controls, followed by a lengthy period of hyperexcitability, and then a further switch to reduced activity. CONCLUSIONS: Complete loss of CNTNAP2 contributes to the pathogenesis of neurodevelopmental disorders through complex changes in several aspects of human cerebral cortex excitatory neuron development that culminate in aberrant neural network formation and function
Detection of infectious baboon cytomegalovirus after baboon-to-human liver xenotransplantation
Xenotransplantation is considered to be a solution for the human donor shortage. However, there is a potential risk of transmitting animal infections from the transplanted organ. The known transmissibility and clinical significance of human cytomegalovirus (HCMV) infection after allotransplantation led us to evaluate whether baboon cytomegalovirus (BCMV) transmission could occur after a baboon-to-human liver xenotransplant. We examined serial blood samples from a baboon liver recipient and isolated replication-competent CMV-like agents on days 29, 36, and 42 after xenotransplantation. BCMV and HCMV DNAs were detected in the day 29 isolate, while only HCMV DNA was detected in the other isolates. This is the first report of detecting a replication-competent virus from a source animal after xenotransplantation and is a concern with regard to potential zoonotic transmission to others
e-SCP-ECG+ Protocol: An Expansion on SCP-ECG Protocol for Health TelemonitoringâPilot Implementation
Standard Communication Protocol for Computer-assisted Electrocardiography (SCP-ECG) provides standardized communication among different ECG devices and medical information systems. This paper extends the use of this protocol in order to be included in health monitoring systems. It introduces new sections into SCP-ECG structure for transferring data for positioning, allergies, and five additional biosignals: noninvasive blood pressure (NiBP), body temperature (Temp), Carbon dioxide (CO2), blood oxygen saturation (SPO2), and pulse rate. It also introduces new tags in existing sections for transferring comprehensive demographic data. The proposed enhanced version is referred to as e-SCP-ECG+ protocol. This paper also considers the pilot implementation of the new protocol as a software component in a Health Telemonitoring System
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