Genotypes of the clones in studied at the 13 heterozygous loci.

<p>Polymorphism is indicated in bold font.</p><p>Genotypes of the clones in studied at the 13 heterozygous loci.</p

Schematic presentation of the Pinot haplotypes determined by genetic analysis.

<p>Solid grey line corresponds to the ‘white’ haplotype and solid black line to the ‘colored’ haplotype. Dotted lines symbolize deletion or unknown sequences. The boxes represent <i>VvmybA</i> genes: A1: <i>VvmybA1</i> and A2: <i>VvmybA2</i>. The grey triangle indicates the insertion. Positions on chromosome 2 are given en Mb according to the 12X genome sequence.</p

Scheme of evolutionary mechanism of the pinot clones.

<p>The propagation of a mutated cell of the meristem (★ causes the formation of a mericlinal sector, then the complete invasion of a cell layer created a periclinal chimera. Cellular displacement from the L2 to the L1 cell layers (D) and less frequent cellular rearrangements (R) from the L1 to the L2 cell layers lead to the homogenization of the cell layers and to the loss of the chimeric state. PB: Pinot blanc, PG: Pinot gris, PN Pinot noir.</p

Genetic linkage map of the Pinot noir 162 chromosome 2.

<p>Positions of the markers along the chromosome 2 are given in cM and <i>Mb</i> (in italics).</p

Models for pathways proposed to explain the non-canonical ‘white’ haplotypes.

<p>These models are based on the repair of DSBs. After induction of the double-strand break in the acceptor molecule, in that case the ‘colored’ haplotype (solid black line), the ends are processing to yield 3’single-strands tails. Then, the 3’ends invades the double-stranded donor molecule, here the ‘white’ haplotype (solid grey line) and repair synthesis occurs. For the further processing of the intermediate two possible outcomes can be envisaged. For the formation of w188-1: the acceptor molecule is elongating, possibly up to the homology of the second 3’end of the DSB followed by the insertion of a genomic sequence copied from elsewhere into the break. For the formation of w188-2: the acceptor molecule is elongating up to the end of the chromosome using the invading donor sequence as template.</p