3 research outputs found
Faddeev-Senjanovic Quantization of SU(n) N=2 Supersymmetric Gauge Field System with Non-Abelian Chern-Simons Topological Term and Its Fractional Spin
Using Faddeev-Senjanovic path integral quantization for constrained Hamilton
system, we quantize SU(n) N=2 supersymmetric gauge field system with
non-abelian Chern-Simons topological term in 2+1 dimensions, and use
consistency of a gauge condition naturally to deduce another gauge condition.
Further, we get the generating functional of Green function in phase space,
deduce the angular momentum based on the global canonical Noether theorem at
quantum level, obtain the fractional spin of this supersymmetric system, and
show that the total angular momentum has the orbital angular momentum and spin
angular momentum of the non-abelian gauge field. Finally, we find out the
anomalous fractional spin and discover that the fractional spin has the
contributions of both the group superscript components and the A_0^s (x)
charge.Comment: 14 page
Transcriptome regulation and chromatin occupancy by E2F3 and MYC in mice
International audienceE2F3 and MYC are transcription factors that control cellular proliferation. To study their mechanism of action in the context of a regenerating tissue, we isolated both proliferating (crypts) and non-dividing (villi) cells from wild-type and Rb depleted small intestines of mice and performed ChIP-exo-seq (chromatin immunoprecipitation combined with lambda exonuclease digestion followed by high-throughput sequencing). The genome-wide chromatin occupancy of E2F3 and MYC was determined by mapping sequence reads to the genome and predicting preferred binding sites (peaks). Binding sites could be accurately identified within small regions of only 24 bp-28 bp long, highlighting the precision to which binding peaks can be identified by ChIP-exo-seq. Forty randomly selected E2F3- and MYC-specific binding sites were validated by ChIP-PCR. In addition, we also presented gene expression data sets from wild type, Rb-, E2f3- and Myc-depleted crypts and villi within this manuscript. These represent comprehensive and validated datasets that can be integrated to identify putative direct targets of E2F3 and MYC involved in the control of cellular proliferation in normal and Rb-deficient small intestines