10 research outputs found
Synthesis of some new type of thiazolyl coumarins
473-4753-(2-Bromoacetyl)coumarins
react with thiosemicarbazide in the presence of acetophenone to give
[3-(2-hydrazino-4-
thiazolyl)coumarino]-phenylmethyl
methines 1 in a single step.
These compounds can also be obtained by the condensation
of
acetophenone thiosemicarbazones
with 3-(2-bromoacetyl)
coumarins in anhyd. ethanol
and dimethyl formarnide.
Condensation of various
3-(2-bromoacetyl) coumarins with
guanyl thiourea in the
presence of anhyd. ethanol and dimethyl
formamide yields
[3-(2-arnino-4-thiazolyl) coumarino]diamino
methine 2. The structural assignment of the
products is based on elemental analyses and spectral (IR, PMR and MS) data.</span