Antiretroviral therapy (ART) substitution among HIV/AIDS patients visiting Sanjiwani hospital, Bali

Substitution of long-term ARTs provided to HIV/AIDS patients is common due to the ART adverse events. The study aims to describe the reason for ART substitution among HIV/AIDS patient at Sanjiwani Hospital Bali. A retrospective study was conducted of the medical records of HIV/AIDS patients at Sanjiwani hospital Bali, during 2006–2018. Clinical data were retrieved from the medical records and pre sented as descriptive data. Over 12 years, 1,112 HIV/AIDS patients were evaluated in the study. The ART regimens were zidovudine-based ART, tenofovir-based ART, and stavudine-based, at 12.2%, 87.3%, 0.5%, respectively. There was 2.2% switching of ART during the study period. The most common reason for switching was anemia (48%), fol lowed by reduction of kidney function (28%), allergic reaction (16%), and 4% of nausea and suspected failure to ART clinically. We highlight that anemia is the main reason for ART substitution among HIV/AIDS patients