EVALUATION OF EFFICACY OF OOSHAKADI LEKHANA BASTI IN HYPERLIPIDAEMIA - A SINGLE BLINDED RANDOMIZED CONTROLLED STUDY

Disorders of lipid metabolism and obesity are reported by 30% to 40% with increased prevalence. These conditions are co-related with Medo-pradoshajavikara - a condition leading for excess formation of Meda (lipids) directly from Amarasa Dhatu (improperly formed chyle) and travel all over body through blood circulation. This stage is compared to hyperlipidaemia where it is defined as excess circulation of lipids in blood. The present study highlights the efficacy of Ooshakadi Lekhana Basti (type of therapeutic enema) processed by Ooshakadigana Dravyas (alkaline substances). Ooshaka (alkaline sand) was special drug and used almost for first time which is synonymously known as Kshara Mrittika. A single blinded controlled study has been conducted on 45 patients randomized in to three groups each containing 15 patients. The control drug was atrovastin. Average mean reduction of lipids were found statistically significant (p<0.05) in the experimental groups over control group in all types of lipids except HDL which has presented increase pattern. Hence the study establishes the efficacy of Ooshakadi Lekhana Basti in hyperlipidaemia of obese and non-obese patients

IN-VIVO TOXICITY EVALUATION OF SHILA SINDOOR

Ayurveda advocates the use of Rasoushadhis (metallic preparations) along with herbal preparations. Unprocessed metals and minerals like mercury and arsenic are highly toxic. Shila Sindoor is one of the Rasoushadhi being possessed with mercury, sulphur and arsenic disulphide as ingredients. In this study 12 rats were selected randomly from stock colony and divided into 2 equal groups of 6 rats each of group-I (vehicle control) and group-II (treatment group). Group-I rats were treated orally with 0.5ml of compound consisting of 3 parts of de-ionized water and 2 parts of honey. Group-II rats were administered with 0.5ml of compound similar to group-I, vortexed with test compound Shila Sindoor (250mg/Kg body weight) for 14 consecutive days to evaluate the toxic effects of Shila Sindoor. There was no morbidity or mortality during the study. Liver and kidney are the two major vital organs to maintain metabolism and protect human body by eliminating the toxins or deposit in these organs to defend other organs of body from toxicity. The results suggested that body weight, 13 different blood parameters like WBC, RBC, platelet count etc., 8 types of biochemical parameters like SGOT, SGPT, creatinine, urea etc., and lipid-peroxidation of group-II were not statistically significant in comparison with group-I. The histopathological study of kidney and liver of both groups revealed normal histology. In this paper genuine effort is put forth to appraise the safety of Rasoushadhis after meticulous process as described in Ayurveda. The result evinced that drug Shila Sindoor is safe for consumption at treatment dose as prescribed in classics

A holistic approach to the management of Erb′s palsy

A 4.5-month-old female baby, presenting with complete paralysis of right upper limb with typical waiter′s tip deformity, diagnosed as Erb′s palsy was brought to Sri Ganapati Sachchidananda Hospital. Patient was treated with an integrated approach of physiotherapy and Ayurvedic treatment with an intention of aiding faster recovery of the patient to lead a near normal life. As per Ayurvedic classics, this condition can be correlated to Ekangavata (Vata effecting any one part of the body), which is Apatarpana in nature (diseases with deprived growth of body tissue). Hence, the choice of treatment is Santarpana Chikitsa (nourishing treatment). Santarpana Bahyopakramas (nourishing external treatment modalities) such as Ashwagandhabalalakshadi Taila (Ayurvedic medicated oil) Abhyanga (oleation therapy) and Shastikashali Anna Lepa (application of processed rice paste) were administered along with electrical stimulation (physiotherapy modality), both galvanic and faradic current in three sessions. Appreciable results were observed in the form of reduction of disparity in length and mid-arm circumference of right upper limb compared to unaffected left upper limb and the muscle power too improved from zero to four, facilitating patient to near normal movement

Analysis of Virechana karma with Danti avaleha: A retrospective study

Virechana (therapeutic purgation) is a common procedure that is widely practiced among the panchakarma treatments (pentad treatments). Various Virechaka dravyas (purgative drugs) have been described for Virechana. Even after critical analysis of Virechaka dravyas in the literature, still there is difficulty in the fixation of dose. Hence, the retrospective analysis of varied outcomes of Virechana with Danti (Baliospermum montanum) avaleha (linctus) is discussed in this paper. The study included twenty-seven case reports of patients who were administered Virechana with Danti avaleha. These case reports are of patients suffering from various ailments such as irregular menstrual cycles, polycystic ovarian syndrome, primary and secondary infertility, and psoriasis. Danti avaleha was administered at dose of 10 g and 5 g in the Krura (~strong) and Madhyama (~moderate/normal) Koshta (~GI tract) patients, respectively. Among seven Krura koshta patients, three of them resulted with Pravara (excellent) Shuddhi and other four resulted with Madhyama (medium) Shuddhi. In twenty Madhyama koshta patients, sixteen of them resulted with avara (minimum) Shuddhi and remaining four patients resulted with Madhyama shuddhi. Complications like Udara shoola (spasmodic pain of abdomen) and Vamana (emesis) were observed during Virechana. Majority of the patients suffered with Udara shoola were of Madhyama koshta. Vamana was seen in both Krura and Madhyama koshta patients. Irrespective of the type of Shuddhi and complications, all the patients resulted with Samyak Kaphaantiki Virikta lakshana (signs of perfect purgation with end expulsion of Kapha). The study concluded that the Krura koshta patients were tolerable for dose of 10 g and are expected to attain Pravara Shuddhi. Whereas Madhyama koshta patients were intolerable even to mild dose of 5 g, producing Avara shuddhi