105 research outputs found

    Doubly isogenous genus-2 curves with Dâ‚„-action

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    We study the extent to which curves over finite fields are characterized by their zeta functions and the zeta functions of certain of their covers. Suppose C and C are curves over a finite field K, with K-rational base points P and P , and let D and D be the pullbacks (via the Abel–Jacobi map) of the multiplication-by-2 maps on their Jacobians. We say that (C, P) and (C , P ) are doubly isogenous if Jac(C) and Jac(C ) are isogenous over K and Jac(D) and Jac(D ) are isogenous over K. For curves of genus 2 whose automorphism groups contain the dihedral group of order eight, we show that the number of pairs of doubly isogenous curves is larger than na¨ıve heuristics predict, and we provide an explanation for this phenomenon

    Oregon Medicaid Expenditures after the 2014 Affordable Care Act Medicaid Expansion: Over-time Differences among New, Returning, and Continuously Insured Enrollees

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    Background—There is interest in assessing healthcare utilization and expenditures among new Medicaid enrollees after the 2014 Medicaid expansion. Recent studies have not differentiated between newly enrolled individuals and those returning after coverage gaps. Objectives—To assess healthcare expenditures among Medicaid enrollees in the 24 months after Oregon’s 2014 Medicaid expansions and examine whether expenditure patterns were different among the newly, returning, and continuously insured. Research Design—Retrospective cohort study using inverse-propensity weights to adjust for differences between groups. Subjects—Oregon adult Medicaid beneficiaries insured continuously from 2014-2015 who were either newly, returning, or continuously insured. Measures—Monthly expenditures for inpatient care, prescription drugs, total outpatient care, and subdivisions of outpatient care: emergency department (ED), dental, mental and behavioral health (MBH), primary care (PC), and specialist care. Results—After initial increases, newly and returning insured outpatient expenditures dropped below continuously insured. Expenditures for ED and dental services among the returning insured remained higher than among the newly insured. Newly insured MBH, PC, and specialist expenditures plateaued higher than returning insured. Prescription drug expenditures increased over time for all groups, with continuously insured highest and returning insured lowest. All groups had similar inpatient expenditures over 24 months post-Medicaid expansion. Conclusions—Our findings reveal that outpatient expenditures for new non-pregnant, non-dual-eligible Oregon Medicaid recipients stabilized over time after meeting pent-up demand, and prior insurance history affected the mix of services that individuals received. Policy evaluations should consider expenditures over at least 24 months and should account for enrollees’ prior insurance histories

    Effects of surface morphologies on flow behavior in karst condjuits

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/69257/1/BirdandCurl_2009.pd

    Computerized cognitive training for older diabetic adults at risk of dementia: Study protocol for a randomized controlled trial

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    Introduction Older adults with type 2 diabetes are at high risk of cognitive decline and dementia and form an important target group for dementia risk reduction studies. Despite evidence that computerized cognitive training (CCT) may benefit cognitive performance in cognitively healthy older adults and those with mild cognitive impairment, whether CCT may benefit cognitive performance or improve disease self-management in older diabetic adults has not been studied to date. In addition, whether adaptive difficulty levels and tailoring of interventions to individuals' cognitive profile are superior to generic training remains to be established. Methods Ninety community-dwelling older (age ≥ 65) diabetic adults are recruited and randomized into a tailored and adaptive computerized cognitive training condition or to a generic, nontailored, or adaptive CCT condition. Both groups complete an 8-week training program using the commercially available CogniFit program. The intervention is augmented by a range of behavior-change techniques, and participants in each condition are further randomized into a global or cognition-specific phone-based self-efficacy (SE) condition, or a no-SE condition. The primary outcome is global cognitive performance immediately after the intervention. Secondary outcomes include diabetes self-management, meta-memory, mood, and SE. Discussion This pilot study is the first trial evaluating the potential benefits of home-based tailored and adaptive CCT in relation to cognitive and disease self-management in older diabetic adults. Methodological strengths of this trial include the double-blind design, the clear identification of the proposed active ingredients of the intervention, and the use of evidence-based behavior-change techniques. Results from this study will indicate whether CCT has the potential to lower the risk of diabetes-related cognitive decline. The outcomes of the trial will also advance our understanding of essential intervention parameters required to improve or maintain cognitive function and enhance disease self-management in this at-risk group.This study was conducted with the support of an MHS grant to Michal Schnaider-Beeri (grant no. 25860). The funding source played no role in the design and implementation of the trial, analysis and interpretation of the data, or preparation of the article. The CCT platform was donated by CogniFit. CogniFit or its employees played no role in the design and implementation of the trial, analysis and interpretation of the data, or preparation of the article. Rachel Bloom is supported by the Vice-Chancellor Award awarded to her by Bar Ilan University. Alex Bahar-Fuchs is supported by an Australian National Health and Medical Research Council fellowship (grant no. 1072688)

    The Iowa Homemaker vol.23, no.2

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    Presenting 1943 Veishea, Dorothy Walker, page 1 Keeping Up With Today, Margaret Ralston, page 4 Letter from a SPAR, Mary Leffler, page 5 Demand for Day Nurseries, Marjory Gillingham, page 6 Freezing Preserves Victory Foods, Frances Madigan, page 7 Gardens Challenge Faculty, Lois Stewart, page 8 Food Affects Morale, Dr. Lowell Selling, page 9 Vicky Favors Simplicity, Mary Lou Springer, page 10 An Economist Interprets Food Problems, Dorothy Conquest, page 11 Grooming for a Career, Mary Schmidt, page 12 Students Enlist, Annette DeLay, page 13 The Red Cross Canteen Corps Mobilize, page 14 What’s New in Home Economics, Lily Houseman, page 16 Women to Know, Josephine Ahern, page 18 Home Economists Plan for the WAAC, Frances Kerekes, page 19 Canada Organizes for Nutrition, Mary Ellen Sullivan, page 20 Experience Gleaned, Janet Russell, page 22 Eggs Spell Good Nutrition, Marian Loofe, page 23 Commissioned in Dietetics, Victoria McKibben, page 24 Across Alumnae Desks, Virginia Carter, page 26 Whole Grains Fortify, Shirley Like, page 28 Designed for Art Majors, JoAnne Nicholson, page 29 Alums in the News, Rachel Ann Lusher, page 31 Meals on the Move, Catherine Tidemanson, page 3

    The Association of Depressive Symptoms With Brain Volume Is Stronger Among Diabetic Elderly Carriers of the Haptoglobin 1-1 Genotype Compared to Non-carriers

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    Aim: Depression is highly prevalent in type 2 diabetes and is associated with lower adherence to medical treatments, worse glycemic control, and increased risk for diabetes-related complications. The mechanisms underlying depression in type 2 diabetes are unclear. The haptoglobin (Hp) genotype is associated with type 2 diabetes related complications including increased risk for cerebrovascular pathology and worse cognitive performance. Its relationship with depression is unknown. We investigated the role of Hp genotype on the association of depression with brain and white matter hyperintensities (WMH) volumes.Methods: Depressive symptoms (measured with the 15-item Geriatric Depression Scale), brain MRI, and Hp genotypes, were examined in elderly subjects with type 2 diabetes [29 (13.8%) Hp 1–1 carriers and 181 (86.2%) non-carriers]. The interaction of Hp genotype with number of depressive symptoms on regional brain measures was assessed using regression analyses.Results: The significant interactions were such that in Hp 1–1 carriers but not in non-carriers, number of depressive symptoms was associated with overall frontal cortex (p = 0.01) and WMH (p = 0.04) volumes but not with middle temporal gyrus volume (p = 0.43).Conclusions: These results suggest that subjects with type 2 diabetes carrying the Hp 1–1 genotype may have higher susceptibility to depression in the context of white matter damage and frontal lobe atrophy. The mechanisms underlying depression in diabetes may differ by Hp genotype

    Depressive Symptoms Are Associated with Cognitive Function in the Elderly with Type 2 Diabetes

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    Background: Type 2 diabetes (T2D) is a metabolic condition associated with poor clinical and cognitive outcomes including vascular disease, depressive symptoms, cognitive impairment, and dementia. In the general elderly population, depression has been consistently identified as a risk factor for cognitive impairment/decline. However, the association between depression and cognitive function in T2D has been understudied. Objective: We investigated the association between depression and cognitive function in a large sample of cognitively normal elderly with T2D. Methods: In this cross-sectional study, we examined 738 participants, aged 65–88 years old, enrolled in the Israel Diabetes and Cognitive Decline study. For each cognitive domain (Episodic Memory, Executive Function, Attention/Working Mem- ory, Language/Semantic Categorization) and Overall Cognition, multiple linear regressions assessed its association with depression (score greater than 5 on the 15-item version of the Geriatric Depression Scale [GDS]), adjusting for age, sex, and education. Results: Depression (n = 66, 8.9%) was associated with worse performance on tasks of Executive Function (p = 0.004), Language/Semantic Categorization (p \u3c 0.001), and Overall Cognition (p \u3c 0.002), but not Episodic Memory (p = 0.643) or Attention/Working Memory (p = 0.488). Secondary analyses using GDS as a continuous variable did not sub- stantially change the results. Adjusting also for a history of antidepressant medication use slightly weakened the findings. Conclusion: Significant associations of depression with several cognitive domains and Overall Cognition even in cognitively normal elderly with T2D, suggest that depression may have a role in impaired cognitive function in T2D, which may be attenuated by antidepressants

    Use of Quality Improvement Strategies Among Small to Medium-Size US Primary Care Practices

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    PURPOSE Improving primary care quality is a national priority, but little is known about the extent to which small to medium-size practices use quality improvement (QI) strategies to improve care. We examined variations in use of QI strategies among 1,181 small to medium-size primary care practices engaged in a national initiative spanning 12 US states to improve quality of care for heart health and assessed factors associated with those variations. METHODS In this cross-sectional study, practice characteristics were assessed by surveying practice leaders. Practice use of QI strategies was measured by the validated Change Process Capability Questionnaire (CPCQ) Strategies Scale (scores range from −28 to 28, with higher scores indicating more use of QI strategies). Multivariable linear regression was used to examine the association between practice characteristics and the CPCQ strategies score. RESULTS The mean CPCQ strategies score was 9.1 (SD = 12.2). Practices that participated in accountable care organizations and those that had someone in the practice to configure clinical quality reports from electronic health records (EHRs), had produced quality reports, or had discussed clinical quality data during meetings had higher CPCQ strategies scores. Health system–owned practices and those experiencing major disruptive changes, such as implementing a new EHR system or clinician turnover, had lower CPCQ strategies scores. CONCLUSION There is substantial variation in the use of QI strategies among small to medium-size primary care practices across 12 US states. Findings suggest that practices may need external support to strengthen their ability to do QI and to be prepared for new payment and delivery models

    Computerized cognitive training for older adults at higher dementia risk due to diabetes: Findings from a randomized controlled trial

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    To evaluate the effects of adaptive and tailored computerized cognitive training on cognition and disease self-management in older adults with diabetesThis work was supported by Maccabi Health Services (MHS; grant no. 25860 to M.S.B.). The funding source played no role in the design and implementation of the trial, analysis and interpretation of the data, or preparation of the manuscript. The CCT platform was donated by CogniFit. CogniFit or its employees played no role in the design and implementation of the trial, analysis and interpretation of the data, or preparation of the manuscript. R.B. was supported by the Vice-Chancellor Award from Bar Ilan University, Israel. A.B-F. was supported by an Australian National Health and Medical Research Council fellowship (grant no. 1072688). M.S.B. was supported by the National Institute on Aging (grant no. R01-AG-034087). A.H. is an employee of MHS who provided funding for this study. The authors declare that they have no competing interests
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