An Image of Hope

A narrative about overcoming a chronic illness and the importance of interprofessional health car

Haitian Life, Traditions, and Culture in the Works of Edwidge Danticat

Throughout the past couple of years of my life, Haiti has become increasingly significant in terms of how I see myself and how I see the world around me. My interest in Haiti began on my first mission trip to Kay Mari in 2015 through an organization, Haiti 180. Haiti 180 was created by Sean Forrest, who’s first trip to Haiti was in 2002, providing medical services to the poor. While in Haiti, Forrest visited an orphanage and was moved by the heartfelt compassion and heroic efforts of the caretakers. It disturbed him to notice, however, that for most of the day the children had little activity or physical contact. When Forrest returned home to the States, he asked God to let him build an orphanage for the children of Haiti that would be a true home. The problem was … how could this be done, with no land, no resources, and no funding. With the help of an amazing team, Forrest produced a powerful concert that raised $20,000 for the poor of Haiti, and then dedicated the proceeds of two summer camps to purchase the land and a home for an adopted Haitian family. Today, the orphanage, Kay Mari, is complete and bursting with happy children, the world-class school is full of life and learning, the chapel is a beautiful anchor for spiritual life in the village, a warm and inviting elderly home, Kay Martina, and the medical facility is standing strong

Henri Temianka (Concert Programs)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_ephemera/1031/thumbnail.jp

Henri Temianka (Concert Programs)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_ephemera/1032/thumbnail.jp

Henri Temianka Correspondence; (coolidge)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/1644/thumbnail.jp

Henri Temianka Correspondence; (coolidge)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_correspondence/3473/thumbnail.jp

pH Dependence and Stoichiometry of Binding to the Fc Region of IgG by the Herpes Simplex Virus Fc Receptor gE-gI

Herpes simplex virus type 1 encodes two glycoproteins, gE and gI, that form a heterodimer on the surface of virions and infected cells. The gE-gI heterodimer has been implicated in cell-to-cell spread of virus and is a receptor for the Fc fragment of IgG. Previous studies localized the gE-gI-binding site on human IgG to a region near the interface between the CH2 and CH3 domains of Fc, which also serves as the binding site for bacterial and mammalian Fc receptors. Although there are two potential gE-gI-binding sites per Fc homodimer, only one gE-gI heterodimer binds per IgG in gel filtration experiments. Here we report production of recombinant human Fc molecules that contain zero, one, or two potential gE-gI-binding sites and use them in analytical ultracentrifugation experiments to show that two gE-gI heterodimers can bind to each Fc. Further characterization of the gE-gI interaction with Fc reveals a sharp pH dependence of binding, with KD values of ~340 and ~930 nM for the first and second binding events, respectively, at the slightly basic pH of the cell surface (pH 7.4), but undetectable binding at pH 6.0. This strongly pH-dependent interaction suggests a physiological role for gE-gI dissociation from IgG within acidic intracellular compartments, consistent with a mechanism whereby herpes simplex virus promotes intracellular degradation of anti-viral antibodies

Henri Temianka (Concert Programs)

This collection contains material pertaining to the life, career, and activities of Henri Temianka, violin virtuoso, conductor, music teacher, and author. Materials include correspondence, concert programs and flyers, music scores, photographs, and books.https://digitalcommons.chapman.edu/temianka_ephemera/1159/thumbnail.jp