Green Chemo-Prevention: An Integrated Review Between Agriculture and Medicine

The isothiocyanate's chemoprevention properties are reported to be present in cruciferous veggies through a variety of mechanisms. Sulforaphane, a phytochemical found in green leafy vegetables, has shown promise in the prevention and treatment of several cancers, including those of the prostate, breast, colon, skin, urinary bladder, and oral cavities. These malignancies include those that affect these organs. This substance is naturally present in broccoli sprouts, kale, cabbage, cauliflower, and garden cress. Broccoli should be a regular part of your diet because it contains a variety of bioactive substances such as vitamins, polyphenols, sulfides, glucosinolates, and antioxidants. Sulforaphane may be used as an inexpensive replacement or dietary supplement for chemo preventive therapy, according to the findings of epidemiological and experimental studies. Phase 2 detoxification enzymes like glutathione transferases, epoxide hydrolase, NAD(P)H: quinone reductase, and glucuronosyltransferases, as well as epoxide hydrolase and epoxide hydrolase, are produced when the body is stimulated. This is a useful tactic for preventing cancer and fending off the harm that electrophiles and reactive oxygen species can cause. Isothiocyanates are widely distributed in the Cruciferae family and Brassica genus of food plants, which include both broccoli and cauliflower. The most typical form of these substances is glucosinolate precursors. Sulforaphane and 4-methylsulfinylbutyl isothiocyanate, two of these isothiocyanates, are particularly powerful inducers of phase 2 enzymes. It is feasible to successfully extract glucosinolates and isothiocyanates from plants by homogenizing them at a temperature of around 50 degrees Celsius in a solution of equal parts dimethyl sulfoxide, dimethylformamide, and acetonitrile. This method avoids the hydrolysis of glucosinolates by myrosinase.   It's interesting to note that glucoraphanin, the precursor to sulforaphane, is 10–100 times more abundant in 3-day-old sprouts of various cruciferous vegetables, including broccoli and cauliflower than it is in fully grown veggies. Dimethylbenz(a)anthracene-treated rats displayed notable reductions in mammary tumor occurrence, quantity, and rate of growth when fed extracts from 3-day-old broccoli sprouts. These extracts' primary enzyme-inducing components were either glucoraphanin or sulforaphane. As a result, crucifer sprouts might provide an equivalent amount of cancer prevention to eating far larger quantities of the same mature vegetable species

Exclusive measurement of isospin mixing at high temperature in 32S

Exclusive measurement of isospin (I) mixing in 32S at high temperature (T) has been performed utilizing the γ-decay of isovector giant dipole resonance (IVGDR). The degree of isospin mixing was deduced from the ratio of high energy γ-ray cross-sections of 32S and 31P populated at the same temperature and angular momentum (J). Precise temperature was determined by simultaneous measurement of nuclear level density (NLD) parameter and angular momentum. The measured Coulomb spreading width (Γ↓) seems to be independent of temperature and angular momentum. The isospin becomes a good quantum number with increase in temperature. However, when compared with the calculation at high temperature, measured isospin mixing is underpredicted by the calculations. Keywords: Isospin mixing in nuclei, Isovector giant dipole resonance, Statistical theory of nucleus, BaF2 detector

Study of giant dipole resonance in hot rotating light mass nucleus 31P

An exclusive systematic study of the giant dipole resonance (GDR) parameters has been performed in very light mass nucleus P31 in the temperature range of ∼0.8–2.1MeV and average angular momentum of ∼11–16ħ. The high-energy γ rays from the decay of the GDR, evaporated neutrons and γ-ray multiplicities have been measured. The angular distribution of high-energy γ rays has also been measured at Ebeam=42MeV. The GDR parameters, nuclear level density parameter and nuclear temperature were precisely determined by simultaneous statistical model analysis of high-energy γ ray and evaporated neutron spectra. It is observed that the measured width remains roughly constant up to a temperature of ∼1.6MeV. Moreover, the thermal pairing plays no role in describing the GDR width in this open-shell light nucleus at the above-mentioned temperatures and angular momenta. The present measurements provide an excellent platform to extend the applicability of the existing theoretical models down to the very light mass nuclei. Keywords: Isovector giant dipole resonance, Statistical theory of nucleus, BaF2 detector

Spectroscopy of a tetrahedral doubly magic candidate nucleus 70160^{160}_{70}Yb90_{90}

International audienceThe decay scheme of 160Yb nucleus populated in the 148Sm(16O, 4n)160Yb reaction at 90 MeV has been studied. The gamma-coincidence data have been collected by using Indian National Gamma Array (INGA) composed of twenty Compton-suppressed Clover-germanium detectors. Compared to the prior publications, the level scheme has been significantly modified owing to the observation of triple γ-coincidences and the measurements of γ intensities, R θ (asymmetry ratio), directional correlation of oriented states and integrated polarisation directional correlation of oriented states ratios. Theoretical results relevant for the exotic shape-coexistence related to the present context are presented and discussed. They illustrate the consequences of the fact that 160Yb is expected to be a doubly-magic (Z = 70 and N = 90) tetrahedral-symmetry nucleus as predicted by other authors. The historical criteria of identification of such a symmetry in nuclei are critically revisited in the context of the actual measurement and interpretation of its results and the precise new criteria are formulated employing recent results of the Fukuoka-Strasbourg collaboration. The experimental results are interpreted and discussed in detail. Limiting values of branching ratios for transitions observed by other authors but unseen in the present work are estimated. The population criteria of the β and γ vibration bands are revisited and discussed. Although no indication of the presence of the stable tetrahedral configuration has been obtained, arguments are given towards the possible presence of the Y 32 (‘tetrahedral component’) vibrations around the ground-state equilibrium. With the improvement of the spectroscopic information provided by the new data the way is opened for designed experiment(s) based on the unambiguous identification criteria of tetrahedral symmetry presented in this article