18 research outputs found
Iterative deconvolution of teleseismic P waves from the Thessaloniki (N. Greece) earthquake of June 20, 1978
Comparison of the Uptake of Screening Colonoscopy between Physicians and the General Population in Greece
Aim: To evaluate the uptake of screening colonoscopy among physicians as compared to the general population. Methods: Asymptomatic physicians, aged 45-67 years, at average risk for colorectal cancer (CRC), working in the participating National Health System hospitals were asked to complete a questionnaire regarding the uptake of screening colonoscopy. The results were compared to those in a background healthy population, aged 50-75 years, inhabitants of a Greek county, who were offered a free access to a screening colonoscopy program for CRC. High-risk adenomas were those ≥10 mm in diameter or any adenoma, regardless of size, with villous histology or high-grade dysplasia. Results: Overall, 267 of 782 physicians and 402 of 6,534 nonphysicians underwent a screening colonoscopy (uptake rates 34.2 and 6.2% respectively, p = 0.00001). Screening colonoscopy has yielded 4 adenocarcinomas (1.6%), 14 high-risk adenomas (5.5%), and 61 low-risk adenomas (25.7%) in the physicians' group. Corresponding figures in the nonphysician arm were 4 (1), 26 (6.5), and 107 (26.6%), respectively. The main reason among physicians for nonadherence was indifference/negligence (n = 213). Conclusion: The proportion of physicians undergoing screening colonoscopy for CRC is significantly higher compared to the general population; however, it does remain suboptimal. © 2019 S. Karger AG, Basel
Mo1485 – Long-Term Follow-Up After Recurrence of Primary Biliary Cholangitis Following Liver Transplantation: A Single Center Study
1-D Theoretical Modeling for Site Effect Estimations in Thessaloniki: Comparison with Observations
The natural history of COVID-19 in patients with IBD: A nationwide study by the Hellenic Society for the Study of IBD
The natural history of COVID-19 in patients with inflammatory bowel disease: a nationwide study by the Hellenic Society for the study of IBD
OBJECTIVES: COVID-19 has evolved into a global health crisis, variably affecting the management of patients with chronic illnesses. Patients with inflammatory bowel disease (IBD) may represent a vulnerable population due to frequent administration of immune-modifying treatments. We aimed to depict the natural history of COVID-19 infection in Greek patients with IBD at a nationwide level via unbiased reporting of all cases that were registered during the sequential waves of the pandemic. METHODS: Following a national call from the Hellenic Society for the study of IBD, we enrolled all IBD patients with established diagnoses of COVID-19. Clinical and epidemiological data, including COVID-19 modifying factors and IBD-associated therapies, were analyzed against adverse outcomes (hospitalization, ICU admission and death). RESULTS: We identified 154 IBD patients who were diagnosed with COVID-19 (men: 58.4%; mean age=41.7 years [SD = 14.9]; CD: 64.3%). Adverse outcomes were reported in 34 patients (22.1%), including 3 ICU admissions (1.9%) and two deaths (1.3%). Multivariate logistic regression analysis showed that age (OR = 1.04, 95% CI, 1-1.08) and dyspnea at presentation (OR = 7.36, 95% CI, 1.84-29.46) were associated with worse outcomes of COVID-19 infection. In contrast, treatment with biologics, in particular anti-TNF agents, exerted a protective effect against an unfavorable COVID-19 disease course (OR = 0.4, 95% CI, 0.16-0.99). Patients on subcutaneous biologics were more likely to halt treatment due to the infection as compared to those on intravenous biologics. CONCLUSIONS: IBD patients who developed COVID-19 had a benign course with adverse outcomes being infrequent. Treatment with anti-TNF biologics had a protective effect, thus, supporting continuation of therapy during the pandemic. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved
Correlation between damage distribution and ambient noise H/V spectral ratio: the SESAME project results
Source parameters of some large earthquakes in the eastern Mediterranean region based on an itertive maximum entropy technique
The burden and management of anemia in Greek patients with inflammatory bowel disease: a retrospective, multicenter, observational study
Background: Anemia is a common extraintestinal manifestation of
Inflammatory Bowel Disease (IBD) affecting negatively the patients’
quality of life. The aim of this study was to determine the frequency
and real-life management of anemia in IBD patients in Greece.
Methods: This study was conducted in 17 Greek IBD referral centers.
Demographic, clinical, laboratory, IBD and anemia treatment data were
collected and analyzed retrospectively.
Results: A total of 1394 IBD patients [560 ulcerative colitis (UC),
834 Crohn’s disease (CD)] were enrolled. Anemia at any time was reported
in 687 (49.3%) patients of whom 413 (29.6%) had episodic and 274
(19.7%) had recurrent/persistent anemia. Anemia was diagnosed before
IBD in 45 (6.5%), along with IBD in 269 (39.2%) and after IBD in 373
(54.3%) patients. In the multivariate analysis the presence of
extraintestinal manifestations (p = 0.0008), IBD duration (p = 0.026),
IBD related surgeries and hospitalizations (p = 0.026 and p = 0.004
accordingly) were risk factors of recurrent/persistent anemia. Serum
ferritin was measured in 839 (60.2%) IBD patients. Among anemic
patients, 535 (77.9%) received treatment. Iron supplementation was
administered in 485 (90.6%) patients, oral in 142 (29.3%) and
intravenous in 393 (81%).
Conclusions: The frequency of anemia in IBD patients, followed at Greek
referral centers, is approximately 50%. Development of
recurrent/persistent anemia may be observed in 20% of cases and is
independently associated with the presence of extraintestinal
manifestations, IBD duration, IBD related surgeries and
hospitalizations. Anemia treatment is administered in up to [Formula:
see text] of anemia IBD patients with the majority of them receiving
iron intravenously