Minimally invasive treatment of localized prostate cancers. Immediate and long-term complications

Organ-operation are the most promising in the preservation of the quality of life, social adaptation, minimizing intra – and postoperative adverse effects in patients with localized forms of prostate cancer. The clinic UGMU based GBUZ CO 'SOKB №1» with high efficiency using modern techniques such as low-dose brachytherapy (LDR) and high-intensity focused ultrasound (HIFU) ablation in the treatment of localized forms of prostate cancer. During the use of these techniques over 924 patients have been treated, with a minimum of complication and high efficiency.Органосохраняющие операции являются наиболее перспективными в сохранении качества жизни, социальной адаптации, минимизации интра - и послеоперационных негативных последствий у пациентов с локализованными формами рака предстательной железы. В клинике УГМУ на базе ГБУЗ СО «СОКБ №1» с высокой эффективностью применяются современные методики такие как низкодозная брахитерапия (LDR) и высокоинтенсивная фокусированная ультразвуковая (HiFu) абляция при лечении локализованных форм рака предстательной железы. За время использования данных методик пролечено более 924 пациентов, с минимальным количеством осложнений и высокой эффективностью

The geometry of decision-making in individuals and collectives

Choosing among spatially distributed options is a central challenge for animals, from deciding among alternative potential food sources or refuges to choosing with whom to associate. Using an integrated theoretical and experimental approach (employing immersive virtual reality), we consider the interplay between movement and vectorial integration during decision-making regarding two, or more, options in space. In computational models of this process, we reveal the occurrence of spontaneous and abrupt “critical” transitions (associated with specific geometrical relationships) whereby organisms spontaneously switch from averaging vectorial information among, to suddenly excluding one among, the remaining options. This bifurcation process repeats until only one option—the one ultimately selected—remains. Thus, we predict that the brain repeatedly breaks multichoice decisions into a series of binary decisions in space–time. Experiments with fruit flies, desert locusts, and larval zebrafish reveal that they exhibit these same bifurcations, demonstrating that across taxa and ecological contexts, there exist fundamental geometric principles that are essential to explain how, and why, animals move the way they do