Effects of Internal Parasite Infection at Feedlot Arrival on Performance and Carcass Characteristics in Beef Steers

The performance and carcass characteristics of 43 beef steers were evaluated relative to internal parasite burden at feedlot arrival. Despite being effectively dewormed at feedlot entry, cattle with more significant worm burdens on arrival had lesser body weights throughout the feeding period and tended to have more days on feed. Even with a tendency for more days on feed, more heavily infected cattle also tended to have lesser marbling scores, dressing percentages, KPH, and back fat. However, there were no differences in ADG throughout the finishing period, REA, yield grade, or HCW relative to initial worm burden. These data indicate that larger worm burdens at feedlot arrival can have long-term effects on body weight and carcass characteristics even when deworming procedures are successful. This information highlights the importance of internal parasite control during the grazing and growing period

Comparison of Ivermectin and Extended-release Eprinomectin Deworming Treatment on Stocker and Subsequent Feedlot Performance and Carcass Characteristics of Fall-born Angus Heifers

Severe parasite infections in beef cattle are sometimes associated with decreased growth and performance and clinical disease. Stocker cattle are exposed to many parasites and appropriate deworming strategies can help to minimize parasite burdens when cattle are on grass. Feedlot cattle are often dewormed at arrival and have minimal exposure to additional parasites once placed in the feedlot. The purpose of this study was to evaluate stocker and feedlot performance and carcass characteristics relative to treatment with deworming agents of varying durations of activity

Severe Acute Kidney Injury is Associated with Increased Risk of Death and New Morbidity After Pediatric Septic Shock

Objectives: Acute kidney injury is common in critically ill children; however, the frequency of septic shock-associated acute kidney injury and impact on functional status are unknown. We evaluated functional outcomes of children with septic shock-associated acute kidney injury. Design: Secondary analysis of patients with septic shock from the prospective Life after Pediatric Sepsis Evaluation study. We defined acute kidney injury using Kidney Disease Improving Global Outcomes criteria, comparing patients with absent/Stage 1 acute kidney injury to those with Stage 2/3 acute kidney injury (severe acute kidney injury). Our primary outcome was a composite of mortality or new functional morbidity at day 28 of hospitalization or discharge. We also assessed poor long-term outcome, defined as mortality or a persistent, serious deterioration in health-related quality of life at 3 months. Setting: Twelve academic PICUs in the United States. Patients: Critically ill children, 1 month to 18 years, with community-acquired septic shock requiring vasoactive-inotropic support. Interventions: None. Measurements and main results: More than 50% of patients (176/348) developed severe acute kidney injury; of those, 21.6% (38/176) required renal replacement therapy. Twice as many patients with severe acute kidney injury died or developed new substantive functional morbidity (38.6 vs 16.3%; p < 0.001). After adjustment for age, malignancy, and initial illness severity, severe acute kidney injury was independently associated with mortality or new substantive morbidity (adjusted odds ratio, 2.78; 95% CI, 1.63-4.81; p < 0.001). Children with severe acute kidney injury had poorer health-related quality of life at 3 months (adjusted effect size 2.46; 95% CI, 1.44-4.20; p = 0.002). Children with severe acute kidney injury required longer duration of mechanical ventilation (11.0 vs 7.0 d; p < 0.001) and PICU stay (11.7 vs 7.1 d; p < 0.001). Conclusions: Among children with septic shock, severe acute kidney injury was independently associated with increased risk of death or new substantive functional morbidity. Survivors of sepsis with severe acute kidney injury were more likely to have persistent, serious health-related quality of life deterioration at 3 months

Effects of Internal Parasite Infection at Feedlot Arrival on Performance and Carcass Characteristics in Beef Steers

The performance and carcass characteristics of 43 beef steers were evaluated relative to internal parasite burden at feedlot arrival. Despite being effectively dewormed at feedlot entry, cattle with more significant worm burdens on arrival had lesser body weights throughout the feeding period and tended to have more days on feed. Even with a tendency for more days on feed, more heavily infected cattle also tended to have lesser marbling scores, dressing percentages, KPH, and back fat. However, there were no differences in ADG throughout the finishing period, REA, yield grade, or HCW relative to initial worm burden. These data indicate that larger worm burdens at feedlot arrival can have long-term effects on body weight and carcass characteristics even when deworming procedures are successful. This information highlights the importance of internal parasite control during the grazing and growing period.</p

Comparison of Ivermectin and Extended-release Eprinomectin Deworming Treatment on Stocker and Subsequent Feedlot Performance and Carcass Characteristics of Fall-born Angus Heifers

Severe parasite infections in beef cattle are sometimes associated with decreased growth and performance and clinical disease. Stocker cattle are exposed to many parasites and appropriate deworming strategies can help to minimize parasite burdens when cattle are on grass. Feedlot cattle are often dewormed at arrival and have minimal exposure to additional parasites once placed in the feedlot. The purpose of this study was to evaluate stocker and feedlot performance and carcass characteristics relative to treatment with deworming agents of varying durations of activity.</p