Long-lasting insecticide-treated net usage in eastern Sierra Leone - the success of free distribution.

Summary Objective Médecins Sans Frontières (MSF) runs a malaria control project in Bo and Pujehun districts (population 158 000) that includes the mass distribution, routine delivery and demonstration of correct use of free, long-lasting insecticide-treated nets (LLINs). In 2006/2007, around 65 000 LLINs were distributed. The aim of this follow-up study was to measure LLIN usage and ownership in the project area. Methods Heads of 900 randomly selected households in 30 clusters were interviewed, using a standardized questionnaire, about household use of LLINs. The condition of any LLIN was physically assessed. Results Of the 900 households reported, 83.4% owning at least one LLIN. Of the 16.6% without an LLIN, 91.9% had not participated in the MSF mass distribution. In 94.1% of the households reporting LLINs, the nets were observed hanging correctly over the beds. Of the 1135 hanging LLINs, 75.2% had no holes or 10 or fewer finger-size holes. The most common source of LLINs was MSF (75.2%). Of the 4997 household members, 67.2% reported sleeping under an LLIN the night before the study, including 76.8% of children under 5 years and 73.0% of pregnant women. Conclusion Our results show that MSF achieved good usage with freely distributed LLINs. It is one of the few areas where results almost achieve the new targets set in 2005 by Roll Back Malaria to have at least 80% of pregnant women and children under 5 years using LLINs by 2010

How HRM affects corporate financial performance: Evidence from Belgian SMEs.

In this paper, we provide a summary of several results from a study of HRM in small and medium-sized enterprises in Belgium. The central issue is whether the investment in HRM practices for smaller organizations is 'profitable'. This study differs in three ways from existing research. (1) It deals with the results from a survey of organizations with between 10 and 100 employees from various sectors. (2) In composing an index for 'HRM intensity', we started with a different interpretation of HRM practices, which also fits in more closely with the Belgian institutional context. (3) The operationalization of performance is based on a number of financial indicators which also help determine the 'state of health' of a company. Using the results of the survey, we examined the link between the score for HRM intensity, some performance outcomes and the financial performance of the organization using structural equation modeling. The results show that intensive HRM also offers added value for smaller organizations. Firstly, HRM intensification has a highly positive effect on productivity and, through productivity, reduces personnel costs/added value. This effect is sufficiently strong to compensate for the increased costs associated with intensive HRM. On top of this 'compensation effect', HRM intensity also has major effects on the profitability of the company.

How HRM affects corporate financial performance. Evidence from Belgian SMEs. Paper.

Employment; Expected; Managers; Studies; Management; Performance;

How accurate are adolescents in portion-size estimation using the computer tool young adolescents' nutrition assessment on computer (YANA-C)?

Computer-administered questionnaires have received increased attention for large-scale population research on nutrition. In Belgium-Flanders, Young Adolescents' Nutrition Assessment on Computer (YANA-C) has been developed. In this tool, standardised photographs are available to assist in portion-size estimation. The purpose of the present study is to assess how accurate adolescents are in estimating portion sizes of food using YANA-C. A convenience sample, aged 11-17 years, estimated the amounts of ten commonly consumed foods (breakfast cereals, French fries, pasta, rice, apple sauce, carrots and peas, crisps, creamy veloute, red cabbage, and peas). Two procedures were followed: (1) short-term recall: adolescents (n 73) self-served their usual portions of the ten foods and estimated the amounts later the same day; (2) real-time perception: adolescents (n 128) estimated two sets (different portions) of pre-weighed portions displayed near the computer. Self-served portions were, on average, 8 % underestimated; significant underestimates were found for breakfast cereals. French fries, peas, and carrots and peas. Spearman's correlations between the self-served and estimated weights varied between 0.51 and 0.84, with an average of 0.72. The kappa statistics were moderate (> 0.4) for all but one item. Pre-weighed portions were, on average, 15% underestimated, with significant underestimates for fourteen of the twenty portions. Photographs of food items can serve as a good aid in ranking subjects; however, to assess the actual intake at a group level, underestimation must be considered

Experimental investigation of solubility trapping in 3D printed micromodels

Understanding interfacial mass transfer during dissolution of gas in a liquid is vital for optimising large-scale carbon capture and storage operations. While the dissolution of CO2 bubbles in reservoir brine is a crucial mechanism towards safe CO2 storage, it is a process that occurs at the pore-scale and is not yet fully understood. Direct numerical simulation (DNS) models describing this type of dissolution exist and have been validated with semi-analytical models on simple cases like a rising bubble in a liquid column. However, DNS models have not been experimentally validated for more complicated scenarios such as dissolution of trapped CO2 bubbles in pore geometries where there are few experimental datasets. In this work we present an experimental and numerical study of trapping and dissolution of CO2 bubbles in 3D printed micromodel geometries. We use 3D printing technology to generate three different geometries, a single cavity geometry, a triple cavity geometry and a multiple channel geometry. In order to investigate the repeatability of the trapping and dissolution experimental results, each geometry is printed three times and three identical experiments are performed for each geometry. The experiments are performed at low capillary number representative of flow during CO2 storage applications. DNS simulations are then performed and compared with the experimental results. Our results show experimental reproducibility and consistency in terms of CO2 trapping and the CO2 dissolution process. At such low capillary number, our numerical simulator cannot model the process accurately due to parasitic currents and the strong time step constraints associated with capillary waves. However, we show that, for the single and triple cavity geometry

Effecten van individuele HRM-domeinen op de financiële resultaten van een bedrijf: een onderzoek in Belgische KMO's.

Management;

An interdisciplinary -omics study to boost continuous bolaform sophorolipid production

Why are we still using petroleum and palm oil derived surfactants for personal care and cleaning applications when more sustainable biobased surfactants are available? Because of the latter’s high production costs. Hitherto, the production efficiencies of fermentation processes for biosurfactants are often insufficient to be economically viable, which is mainly due to the lack of knowledge about the complex interactions between multiple parameters in (industrial) bioreactors and biosynthetic pathways. In this study, we aim at reducing the production costs for innovative bolaform sophorolipids (BLSL), produced with the yeast Starmerella bombicola ΔsbleΔat. An interdisciplinary polar metabolomics and lipidomics driven strategy was set up to gain insight in bolaform sophorolipid biosynthesis and to substantiate an industrial biosurfactant production process with high volumetric productivity. A novel continuous retentostat bioprocess set-up was investigated. It resulted in a volumetric productivity of 0.63 g∙L-1∙h-1, a 186.36% increase in comparison to previous reports . Unfortunately, this high productivity could not be maintained for more than 543h and the reason for the drop in productivity was investigated by performing a multi-omics study. Whole genome sequencing and subsequent variant analysis discovered no evidence for genomic variations for up to 1306h of retentostat cultivation. To reduce confounding factors, a second independent set-up was performed Hereby, The stirring rate was increased excessively in a fed-batch process and resulted in a permanent loss of BLSL production compared to a control fed-batch process. Untargeted polar metabolomics and lipidomics analyses were subsequently performed on bioreactor broth samples of abovementioned experimental set-ups, in order to define metabolites that are associated with either high or low BLSL productivity.Untargeted fingerprints upon polar metabolomics and lipidomics analyses rendered 22,897 and 21,962 components, respectively. Subsequently, principal component analysis (PCA) and supervised orthogonal partial least squares discriminant analysis (OPLS-DA) were performed. These analyses revealed 139 and 44 discriminating components in the polar metabolomics and lipidomics dataset, respectively. These components are linked to BLSL productivity and therefore subsequent identification and pathway mapping will allow the development of rational strategies for metabolic- and/or process engineering and, in the end, to achieve an economically viable (continuous) production process

Rule induction performance in amnestic mild cognitive impairment and Alzheimer’s dementia: examining the role of simple and biconditional rule learning processes

Introduction: Rule induction tests such as the Wisconsin Card Sorting Test require executive control processes, but also the learning and memorization of simple stimulus–response rules. In this study, we examined the contribution of diminished learning and memorization of simple rules to complex rule induction test performance in patients with amnestic mild cognitive impairment (aMCI) or Alzheimer’s dementia (AD). Method: Twenty-six aMCI patients, 39 AD patients, and 32 control participants were included. A task was used in which the memory load and the complexity of the rules were independently manipulated. This task consisted of three conditions: a simple two-rule learning condition (Condition 1), a simple four-rule learning condition (inducing an increase in memory load, Condition 2), and a complex biconditional four-rule learning condition—inducing an increase in complexity and, hence, executive control load (Condition 3). Results: Performance of AD patients declined disproportionately when the number of simple rules that had to be memorized increased (from Condition 1 to 2). An additional increment in complexity (from Condition 2 to 3) did not, however, disproportionately affect performance of the patients. Performance of the aMCI patients did not differ from that of the control participants. In the patient group, correlation analysis showed that memory performance correlated with Condition 1 performance, whereas executive task performance correlated with Condition 2 performance. Conclusions: These results indicate that the reduced learning and memorization of underlying task rules explains a significant part of the diminished complex rule induction performance commonly reported in AD, although results from the correlation analysis suggest involvement of executive control functions as well. Taken together, these findings suggest that care is needed when interpreting rule induction task performance in terms of executive function deficits in these patients