Validation of <i>Sirt3</i> transcript levels.

<p>QRT-PCR of <i>Sirt3</i> levels (A) comparing BN control rat and congenic strain 1consomic (which has GK chromosome 1 on a BN genetic background), in liver (blue) and BAT (green); (B) left, comparing BAT from BN and three congenic strains, two carrying GK allele of <i>Sirt3</i> (1o and 1h), and one with BN allele of <i>Sirt3</i> (1b); (C) diagram of BN.GK chromosome 1 congenic strains used, with maroon bars representing region of GK chromosome 1 introgressed onto BN background. (Genomic location of <i>Sirt3</i> is indicated.) Results are corrected for expression of housekeeping gene 36B4.</p

Liver deacetylases in the rat liver transcriptome.

<p>Shown are transcripts differentially expressed between BN and GK or 1consomic strains. False Discovery Rates (FDR)<0.05 are in bold (V: Variant in probe).</p

Illumina liver transcripts significantly differentially expressed between GK and BN or 1Consomic strain rats.

<p>Gene ontology descriptions relating to protein acetylation or deacetylation are shown. Transcripts with False Discovery Rates (FDR)<0.05 are in bold.</p