Peranan Ai Dan Fe Dalam Tanah Gambut Terolah Asid Sulfurik Sebagai Agen Penggumpal Dalam Perawatan Larutan Pencelup Tekstil

T anah gam but merupakan tanah organik yang terhasil daripada pengumpulan bahan-bahan tumbuhan yang mengalami p'enguraian separa. Sifatnya yang berkutub dan berliang menjadikannya bahan penjerap yang berpotensi. Salah satu pengubahsuaian kirnia yang dilakukan adalah pengolahan tanah garnbut dengan asid sulfurik supaya keberkesanan penjerapannya dapat ditingkatkan. Kajian ini telah mertialankan pengolahan asid sulfurik ke atas dua jenis tanah gambut tempatan daripada Gunung Jerai, Kedah dan Batu Pahat, Johor untuk melihat keberkesanannya bagi tujuan pengolahan larutan pencelup tekstil. Peat is an organic soil which is. fonned from the accumulation of partially decomposed plant matelials. Peat is always considered as a potential adsorbent due to its polar and porous characteristics. One of the chemical modifications nonnally done in order to improve its adsorptiVe properties is sulfuric acid treatmcnt. This research had used two local sulfuric acid treated peats from Gunung Jerai, Kedah and Batu Pallat, Johor to study their effectiveness in treating textile dye solutions

Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity.

Genome rearrangements, a hallmark of cancer, can result in gene fusions with oncogenic properties. Using DNA paired-end-tag (DNA-PET) whole-genome sequencing, we analyzed 15 gastric cancers (GCs) from Southeast Asians. Rearrangements were enriched in open chromatin and shaped by chromatin structure. We identified seven rearrangement hot spots and 136 gene fusions. In three out of 100 GC cases, we found recurrent fusions between CLDN18, a tight junction gene, and ARHGAP26, a gene encoding a RHOA inhibitor. Epithelial cell lines expressing CLDN18-ARHGAP26 displayed a dramatic loss of epithelial phenotype and long protrusions indicative of epithelial-mesenchymal transition (EMT). Fusion-positive cell lines showed impaired barrier properties, reduced cell-cell and cell-extracellular matrix adhesion, retarded wound healing, and inhibition of RHOA. Gain of invasion was seen in cancer cell lines expressing the fusion. Thus, CLDN18-ARHGAP26 mediates epithelial disintegration, possibly leading to stomach H(+) leakage, and the fusion might contribute to invasiveness once a cell is transformed. Cell Rep 2015 Jul 14; 12(2):272-285

Antenatal Steroids and the IUGR Fetus: Are Exposure and Physiological Effects on the Lung and Cardiovascular System the Same as in Normally Grown Fetuses?

Glucocorticoids are administered to pregnant women at risk of preterm labour to promote fetal lung surfactant maturation. Intrauterine growth restriction (IUGR) is associated with an increased risk of preterm labour. Hence, IUGR babies may be exposed to antenatal glucocorticoids. The ability of the placenta or blood brain barrier to remove glucocorticoids from the fetal compartment or the brain is compromised in the IUGR fetus, which may have implications for lung, brain, and heart development. There is conflicting evidence on the effect of exogenous glucocorticoids on surfactant protein expression in different animal models of IUGR. Furthermore, the IUGR fetus undergoes significant cardiovascular adaptations, including altered blood pressure regulation, which is in conflict with glucocorticoid-induced alterations in blood pressure and flow. Hence, antenatal glucocorticoid therapy in the IUGR fetus may compromise regulation of cardiovascular development. The role of cortisol in cardiomyocyte development is not clear with conflicting evidence in different species and models of IUGR. Further studies are required to study the effects of antenatal glucocorticoids on lung, brain, and heart development in the IUGR fetus. Of specific interest are the aetiology of IUGR and the resultant degree, duration, and severity of hypoxemia

Maritime Interdiction Operations in Logistically Barren Environments

Includes supplementary materialThis report contains analysis that shows that existing technology exists to improve Maritime Interdiction Operations (MIO) by approximately 30%. Furthermore, analysis contained herein will aid MIO planning for future operations. Since MIOs are an inherently dangerous, but necessary activity with far reaching implications to theater political and economic dynamics, this improvement is of great interest. MIO is a Naval solution to the problems of smuggling weapons, explosives, people and narcotics. MIO, when employed correctly has the potential to save lives and limit economic/political damage.N

Genetic risk of extranodal natural killer T-cell lymphoma: a genome-wide association study

10.1016/S1470-2045(16)30148-6LANCET ONCOLOGY1791240-1247United State