Training In Making Supplementary Foods and Stunting Prevention Education Through Android-Based “Anak Sehat” Digital Application at Kelurahan Petapahan, Lubuk Pakam Sub-District, Deli Serdang Regency

Teaching, carrying out research for the development of science and applying knowledge, all three of which form a single unit known as the Tridharma of Higher Education. Community service is the third dharma of the Tridharma of Higher Education. The existence of community service is actually very important both for the management of the tertiary institution as well as for the existence of the tertiary institution in the community. The community service carried out is "Training on Making Complementary Food for Breastfeeding and Stunting Prevention Counseling Through the Android-Based "Healthy Children" Digital Application in Petapahan Village, Lubuk Pakam District, Deli Serdang Regency" The target group is mothers who have babies aged 12 months to 5 years in Posyandu Working area Petapahan Village, Lubuk Pakam District. Toddlerhood is an important period in the process of human development. Development and growth at that time determines the success of the growth and development of children in the next period. The period of growth and development at this age is a period that takes place quickly and will never be repeated, because it is often called the golden age or the golden age. Therefore, with this PkM activity, it can increase mother's awareness to pay attention to child development and prevent stunting

Appropriateness of Antibiotic Utilization in Hospitalized Post-Surgery Patients

Abstract. One of the most common health problems related to surgery is infection which needs treatment with antibiotics. Inappropriate use of antibiotics results in many problems including microbial resistance, interference of the required clinical outcomes, increasing side effects of the provided antibiotics and health resources utilization, causing toxic effects to the body organs, and even death. This study aimed to evaluate the appropriateness of antibiotic utilization on post-surgery patients admitted to Haji Adam Malik (HAM) Hospital, Medan, Indonesia. This three-month prospective descriptive study was conducted to evaluate the appropriateness of antibiotic utilization based on Gyssens method categorized into appropriate and inappropriate (in terms of dose, interval, route,  too long provision, too short provision, less effective, toxicity, price, and the spectrum), and trustable literatures on post-surgery patients assessed from their medical records (n=31) in HAM Hospital Medan. Most (54.8%) of the patients were females. The study proved that 23 (74.2%) of the patients received appropriate/rational antibiotic therapy and 8 (25.8%) of them received inappropriate antibiotic therapy consisted of problems with: inappropriate dose, 13%; too long duration, 3.2%); too short duration, 29%. More than a quarter of the patients received inappropriate dosages of antibiotics

Antibacterial Activity of Ethyl Acetate Fraction of Passion Fruit Peel (Passiflora Edulis Sims) on Staphylococcus Aureus and Escherichia Coli

North Sumatera is one of the central areas of purple passion fruit production in Indonesia. Processing passion fruit into beverage products (passion fruit juice) produces peel  has not been utilized. The use of passion fruit skin needs to be studied so that it can be useful as a raw material for antibacterial drug preparations. The aim of this study was to determine the phytochemical constituent screening  and antibacterial activity of ethyl acetate fraction of purple passion fruit peel against Staphylococcus aureus and Escherichia coli. Simplicia and ethyl acetate fraction were determinated  its phytochemical properties.  The extraction process by percolation method using ethanol  96% and continue to fractionation process by liquid liquid extraction method using n-hexane and ethyl acetate. The antibacterial activity were tested  against Staphylococcus aureus and Escherichia coli using agar diffusion method with paper discs. The result showed  that  the simplicia characteristic of passion fruit peel  were water content of  8.64%, water soluble extract of  31.69%, ethanol soluble extract of 13.02%, ash total of 7.89%, and insoluble ash in acid of 0.816%. The phytochemical screening simplicia and ethyl acetate fraction showed the presence of flavonoids, glycosides, saponins and tannins. The antibacterial activity test showed that the ethyl acetate fraction has an effective inhibition at the concentration of 100 mg/ml against Staphylococcus aureus and Escherichia coli, it showed dose dependent manner. The ethyl acetate fraction of passion fruit peel (Passiflora edulis Sims) has an antibacterial activity  on Staphylococcus aureus and Escherichia col

Antibacterial activity of Ethanol Extract of Purple Passion Fruit Peel (Passiflora edulis Sims) on Staphylococcus aureus and Escherichia coli

Abstract.North Sumatera is the central production of  purple passion fruit  in Indonesia. Passion fruit was  processing into beverage product that produced passion fruit peel waste. The passion fruit peel has potential effect as a sources of medicine which is need to be examined such as its antibacterial effect. The purpose of this study was to determine the characterization of simplicia, phytochemical screening  and antibacterial activity of ethanol extract of purple passion fruit peel against Staphylococcus aureus and Escherichia coli. The simplicia powder was examined its characteristic include water content, water soluble extract, ethanol soluble extract, total ash and acid insoluble ash assay. The extraction was process by percolation method using ethanol  96% , then tested antibacterial activity against Staphylococcus aureus and Escherichia coli using agar diffusion method with paper discs.The result showed  that  the simplicia characteristic of passion fruit peel  were water content of  8.64%, water soluble extract of  31.69%, ethanol soluble extract of 13.02%, ash total of 7.89%, and insoluble ash in acid of 0.816%. The phytochemical screening simplicia and ethanol extract showed the presence of flavonoid, glycoside, saponin, tannin and steroid/triterpenoid.The antibacterial activity test showed that the ethanol extract has an effective inhibition at the  concentration of 300 mg/ml against Staphylococcus aureus and Escherichia coli, it showed dose dependent manner.   Keywords: Passiflora edulis Sims, antibacterial, passion fruit peel, Staphylococcus aureus and Escherichia coli       &nbsp

Efficacy of Albendazole and Mebendazole With or Without Levamisole for Ascariasis and Trichuriasis

BACKGROUND: Helminthiasis in school-aged children potentially causing physical growth and intellectual development retardation. Trichuriasis was the most common type of helminthiasis in children. AIM: To investigated the efficacy and side effects of albendazole, albendazole combined with levamisole and mebendazole combined with levamisole for trichuriasis and ascariasis. METHODS: This study was conducted as a double-blind, randomised clinical trial by comparing the efficacy and side effects of albendazole, albendazole combined with levamisole and mebendazole combined with levamisole for trichuriasis. The sample of this study were 180 elementary school students at Deli Serdang Regency State Elementary School, Medan, Indonesia. The study was conducted from April to June 2015. RESULT: The cure rate of helminthiasis on the 7th day was 81.7% after albendazole therapy, 88.3% after albendazole levamisole therapy, and 83.3% after mebendazole combined with levamisole therapy (p = 0.577). Cure rate on the 14th day was 88.3%, 95%, and 91.7% for albendazole, albendazole combined with levamisole, and mebendazole combined with levamisole therapy, respectively (p = 0.418). On the 21th day, the cure rate was 88.3%, 96.7%, and 91.7% (p = 0.230). Combination of albendazole and levamisole showed the highest cure rate, despite the statistically insignificant difference for all groups (p > 0.05). Combination of albendazole combined with levamisole showed better cure rate for mild trichuriasis (95.8%) than albendazole therapy (46.2%) and mebendazole combined with levamisole (83.3%), (p < 0.05). CONCLUSION: Single-dose albendazole, a combination of albendazole and levamisole, and a combination of mebendazole and levamisole had similar efficacy in reducing egg count in helminthiasis. Combination of albendazole and levamisole showed better cure rate for mild trichuriasis and mixed infections. Side effects were similar in all treatment groups

Education and Training on the Utilization of Barangan Banana Peel into Liquid Soap as Home Industry in Siguci Village, North Sumatra

Indonesia one of country that is rich in natural plants that have an active compounds and are used by some people as active substances in the world of cosmetics such as soap. During this time, people only use bananas, limited to the use of the fruit, then the banana’s peel after consumption is only disposed of as waste. Several previous studies have stated that musa acuminata peel contain saponins, flavonoids, alkaloids and tannins. Based on the description, that musa acuminata peel can be used as a antibacterial’s liquid soap. One of the musa acuminata producing areas in North Sumatra is Siguci Village, Deli Serdang Regency. The method used in this service are presentation about musa acuminata, their benefits, the active compounds they contain and the utilization of the waste of musa acuminata peels, as well as providing material on marketing techniques for home industry products. The results of this activity showed that as many as 20 residents were understands and is able to produce liquid soap made from musa acuminata peels, and can make attractive packaging., which can be seen from the results of the pre-test and post-test that were carried out during the educational activity

Training on Herbal Soap Preparation From the Extract Combination of Ketepeng Leaf and Sirih Leaf

The problem of sanitation and hygiene is one of the problems faced by many people in Indonesia, especially in the current state of the Covid 19 pandemic. Not to mention the thing that is faced by the people of the Mabar village, Medan Deli sub-district, Medan City is the poor sanitation and hygiene of the community, especially those who live in dense settlements, so it is necessary to campaign for healthy living behaviors, one of which is through counseling on healthy living behaviors in maintaining personal health during the COVID-19 pandemic. and accompanied by training in the manufacture of antibacterial soap to increase public interest and awareness regarding the importance of healthy living. Soap products have developed into a primary need in today's society. These products are used every day by all levels of society, both upper, middle, and lower classes. The partners involved in community service are community groups in Neighborhood IX, Mabar sub-district, Medan Deli sub-district, Medan City. which is quite potential to be developed through a training program for making antibacterial herbal soaps, one of which is made from ketepeng leaves and betel leaves which are widely believed by the community to be effective in curing skin diseases. Several studies have proven that ketepeng and betel leaves have high antibacterial activity which have the potential to be developed into antibacterial soap products.Housewives and teenagers of productive age who are the targets of this service do not yet have productive activities. This training program is expected to provide business opportunities to the community so that it can improve the economy. The soap products produced can be used to meet household needs or can be sold to the surrounding community. With training in making antibacterial herbal soaps, expenses can be reduced and even can improve the household economy

The Relationship between Hypertension and Cognitive Function Impairment in the Elderly

BACKGROUND: Hypertension is still a health problem both in developed and developing countries. Hypertension can cause various complications; one of them is cognitive function impairment. AIM: This study aimed to look at the relationship of hypertension with cognitive function. This research can also be useful to help optimise the health of the elderly, maximise quality of life and avoid hypertension as a risk factor for cognitive impairment in the elderly at the Karya Kasih Nursing Homes, Medan from May to June 2018. METHODS: This research was carried out by analytic observational with cross-sectional research approach. In this study, 57 elderly from Karya Kasih Nursing Homes Medan who met the inclusion and exclusion criteria participated. Assessment of cognitive function used Mini-Mental State Examination (MMSE), Six Item Cognitive Impairment Test (6CIT) and Abbreviated Mental Test Score (AMT) instruments. RESULT: This study obtained a significant relationship between the history of hypertension with impaired cognitive function (p = 0.003). The results of the cognitive function examination with MMSE showed that among 57 elderly, 16 people (43.2%) were normal and 21 people (56.8%) had impaired cognitive function in the first degree hypertension group, besides that, 3 people were normal (15%) and 7 people (85%) had impaired cognitive function in the second degree hypertension group (p = 0.031). Based on the result of mild and severe cognitive function impairment, among 12 people (57.1%) and 9 people (42.9%) had a mild and severe cognitive function impairment, respectively, in first-degree hypertension. 3 people (17.6%) and 14 people (82.4%) had a mild and severe cognitive function impairment, respectively, in the second-degree hypertension (p = 0.013). The 6-CIT instrument also showed a significant relationship between the severity of hypertension and impaired cognitive function (p = 0.027), and there was no significant relationship with AMT instruments (p = 0.078). CONCLUSION: There was a relationship between the history or duration and degree of hypertension with cognitive dysfunction in the elderly at the Karya Kasih Nursing Home Medan

Evaluation of Mother's Knowledge about Stunting and Observation of Stunting Incidents Based on the Growth of Toddlers at Posyandu Anggrek in Petapahan Village, Lubuk Pakam District, Deli Serdang Regency

This community service aims to provide education about stunting and its prevention in order to increase awareness of mothers so that they can help their children in a period of normal growth and development while reducing the incidence of stunting in Indonesia. This community service activity is carried out by providing counseling related to stunting prevention and filling out questionnaires, especially for mothers who have babies aged 12 months to 5 years at Posyandu Anggrek to determine the effect of this activity on the level of knowledge of mothers regarding stunting issues.The community service carried out is " Evaluation of Mother's Knowledge about Stunting and Observation of Stunting incidents based on the growth of Toddlers at Posyandu Anggrek in Petapahan Village, Lubuk Pakam District, Deli Serdang Regency" The target group is mothers who have babies aged 12 months to 5 years in Posyandu Working area Petapahan Village, Lubuk Pakam District. Toddlerhood is an important period in the process of human development. Development and growth at that time determines the success of the growth and development of children in the next period. The period of growth and development at this age is a period that takes place quickly and will never be repeated, because it is often called the golden age or the golden age. Therefore, with this PkM activity, it can increase mother's awareness to pay attention to child development and prevent stunting

INVESTIGATING THE TOXICITY OF BETALAIN COMPOUNDS: IN SILICO ANALYSIS AND IN VIVO PREDICTIONS FOR STANDARDIZED BETA VULGARIS L. EXTRACT

Objective: Extensive research has been conducted on beetroot's antioxidant, hematoprotective, and cardioprotective properties. However, there currently needs to be more available evidence pertaining to the toxicity assessment of the extract. The toxicity assessment was conducted using both in silico and in vivo methods. Prior to testing, the extracts were standardized in accordance with the guidelines set by the Indonesian Food Drug Authority (BPOM), which is the regulatory authority for food and drugs in Indonesia. Methods: The experimental subjects consisted of 25 male Wistar rats in good health, weighing between 150 and 170 grams. These rats were separated into five groups, each including five rats. Group 1 will serve as the control group, while groups 2 through 5 will be designated as the treatment groups. The analysis of chemical toxicity was conducted using pK-CSM, SwissADME, and Pro-Tox II methodologies.  Results: The results indicated that the standardized ethanol extract contained 4.341% water, 3.67 % total ash, and 1.53 % acid-insoluble ash. Lead (Pb) and cadmium (Cd) were absent at a concentration of 0 parts per million (ppm). Subsequently, the total plate count and yeast mould count were 0.47 5 x 10-4 (CFU/g) and a of 0.382 x 10-4 (CFU/g) respectively. This finding implies that the extract meets BPOM requirement. This study also measured the betalain content of red beetroot, yielding a total concentration of 11.34 0.37 mg/100 gram of sample. Haematological experiments showed that beetroot extract affected rat blood haematology. Compared to the control group, rats given the extract had higher red blood cell and platelet counts. Additionally, the Insilico toxicity test conducted on the active component derived from beetroot revealed LD50 of the compounds ranged from 305 mg/kg so that were categorized into classes IV and presence of hepatotoxic potential. During the in vivo experiment, there has been a notable rise in hepatic and renal parameters. Furthermore, one mortality event occurred in the test subject at a 5,000 mg/kg body weight dosage. Conclusion: Single oral administration of the extract at a dose larger than 5,000 mg per kilogram of body weight does not result in lethal effects, however showed potential toxicity to the liver