5 research outputs found

    Labourers Migrating to the Construction Sector in the State of Haryana: An Analysis of Push and Pull Factors

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    Migration is a global phenomenon which has a vital role in any region’s economic development. This study examines the major push and pull factors of the migration of labourers towards the construction sector of the state of Haryana. Alongside this, the study also sheds light on the socio‐economic conditions of migrant labourers. For this purpose, the study was conducted among 200 migrant labourers engaged in the construction sector of Hisar, Rohtak, Panipat, and Kurukshetra districts of Haryana, with the help of a well-designed questionnaire. It has been found that among the pull factors— higher wages, job opportunities, and consistent work are the major causes of migration. Among push factors, unemployment and low wages are responsible for migration from their native place to their place of destination. Apart from this, wage differences and better living standards also attract labourers to Haryana. So far as improvement in the status of migrants’ is concerned, the study found that the socio-economic status of migrant labourers has improved after they migrated to the state of Haryana

    Human Development and Poverty - a Perspective Across Indian States

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    The ultimate objective of development planning and policies is to increase social welfare and well-being of the society. As income alone is an incomplete measure of well-being of any society, human development attempts to capture quantitative as well as qualitative aspects of human well-being by encapsulating indicatorsof longevity, literacy and a decent standard of living. Human development is about enlarging choices, whereas poverty implies denial to the opportunities and choices most basic to human development. The main concern of this paper is to examine the transformation of development efforts into the well- being of the society, with special reference to India. Here an attempt has been made to find complementary between Human Development Index (HDI) and Multidimensional Poverty Index (MPI) across major Indian states using regression analysis. The negative relationship between the two underlines the need of raising economic and educationalopportunities and their equitable distribution among all the sections of the society

    Proinflammatory Innate Cytokines and Distinct Metabolomic Signatures Shape the T Cell Response in Active COVID-19

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    The underlying factors contributing to the evolution of SARS-CoV-2-specific T cell responses during COVID-19 infection remain unidentified. To address this, we characterized innate and adaptive immune responses with metabolomic profiling longitudinally at three different time points (0–3, 7–9, and 14–16 days post-COVID-19 positivity) from young, mildly symptomatic, active COVID-19 patients infected during the first wave in mid-2020. We observed that anti-RBD IgG and viral neutralization are significantly reduced against the delta variant, compared to the ancestral strain. In contrast, compared to the ancestral strain, T cell responses remain preserved against the delta and omicron variants. We determined innate immune responses during the early stage of active infection, in response to TLR 3/7/8-mediated activation in PBMCs and serum metabolomic profiling. Correlation analysis indicated PBMCs-derived proinflammatory cytokines, IL-18, IL-1β, and IL-23, and the abundance of plasma metabolites involved in arginine biosynthesis were predictive of a robust SARS-CoV-2-specific Th1 response at a later stage (two weeks after PCR positivity). These observations may contribute to designing effective vaccines and adjuvants that promote innate immune responses and metabolites to induce a long-lasting anti-SARS-CoV-2-specific T cell response
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