Effect of <i>KIR</i> and <i>HLA</i> genotypes on the CD4+ T cell count of HIV-1 infected subjects.

<p>(A) Effect of <i>AA</i> versus <i>Bx</i> genotype (n = 81). (B) Combined effect of inhibitory KIR ligand genes <i>Bw4</i> and <i>C1</i> (n = 73). <i>Bw4:C1</i> denotes the simultaneous occurrence of Bw4 and C1. (C) Combined effect of <i>Bx</i> and <i>Bw4:C1</i> genotypes (n = 73). P values represent the statistical significance of the linear regression models using log-transformed CD4+ T cell counts as the dependent variable. Horizontal lines represent median values.</p

Multivariate effects of <i>KIR</i> and <i>HLA</i> genes on the CD4+ T cell count of 81 HIV-1 infected subjects.

<p>Data are calculated by multivariate linear regression analysis using log transformed CD4+ T cell counts as the dependent variable. The estimated effects of the respective terms in the models are shown. Interaction terms, denoting the simultaneous occurrence of two genes, are annotated with “:”.</p>a<p>Data available for 73 of 81 subjects. CI, 95% confidence interval; AIC, Akaike information criterion for goodness of fit; p, statistical significance.</p

Univariate effects of <i>KIR</i> and <i>HLA</i> genes on the CD4+ T cell count and HIV-1 viral load level of 81 HIV-1 infected subjects.

<p>Data are calculated by linear regression analysis using log transformed CD4+ T cell counts and HIV-1 viral load levels as the dependent variables. CI, 95% confidence interval; AIC, Akaike information criterion for goodness of fit; p, statistical significance.</p>a<p>data available for 73 of 81 subjects. p values<0.05 are in bold type.</p