The Research of Reverse-Time Migration for Cross-Hole Seismic

Cross-hole seismic is the leading technology of development seismology, which is still developing and improving. With the development of down-hole acquisition equipment, cross-hole seismic acquisition technology is getting mature, providing better data for imaging. According to the features of cross-hole survey and cross-hole data, we put forward a reverse-time migration method which is suitable for the wave equation for cross-hole seismic data. We propose finite difference scheme of higher order, and then derive its stability condition in cross-hole seismic. The frequency dispersion problem in cross-hole seismic wave field extrapolation is also discussed. Cross correlation imaging condition is used to realize migration, and Laplace filter is applied to remove low-frequency noise from migration section. Thus finite-difference reverse-time migration method for cross-hole seismic is established. Finally, we build geological models with anomalous ellipsoids, and apply cross-hole seismic wave field simulation and migration to them, thus our method proves its effectiveness. When dealing with real cross-hole seismic data with this method, high-resolution migration sections can be achieved.Key words: Cross-hole seismic; Reverse-time migration; Model tes

Respiratory Syncytial Virus Aggravates Renal Injury through Cytokines and Direct Renal Injury

The purpose of this study was to investigate the relationship between renal injury and reinfection that is caused by respiratory syncytial virus (RSV) and to analyze the mechanism of renal injury. Rats were repeatedly infected with RSV on days 4, 8, 14, and 28, then sacrificed and examined on day 56 after the primary infection. Renal injury was examined by transmission electron microscopy and histopathology. The F protein of RSV was detected in the renal tissue by indirect immunofluorescence. Proteinuria and urinary glycosaminoglycans (GAGs), serum levels of albumin, urea nitrogen, and creatinine, secretion of cytokines, T lymphocyte population and subsets, and dendritic cell (DC) activation state were examined. The results showed that renal injury was more serious in the reinfection group than in the primary infection group. At a higher infection dose, 6×106 PFU, the renal injury was more severe, accompanied by higher levels of proteinuria and urinary GAGs excretion, and lower levels of serum albumin. Podocyte foot effacement was more extensive, and hyperplasia of mesangial cells and proliferation of mesangial matrix were observed. The maturation state of DCs was specific, compared with the primary infection. There was also a decrease in the ratio of CD4+ to CD8+T lymphocytes, due to an increase in the percentage of CD8+T lymphocytes and a decrease in the percentage of CD4+T lymphocytes, and a dramatic increase in the levels of IL-6 and IL-17. In terms of the different reinfection times, the day 14 reinfection group yielded the most serious renal injury and the most significant change in immune function. RSV F protein was still expressed in the glomeruli 56 days after RSV infection. Altogether, these results reveal that RSV infection could aggravate renal injury, which might be due to direct renal injury caused by RSV and the inflammatory lesions caused by the anti-virus response induced by RSV