Distribution of Allele and genotype frequency of MAOA gene.

<p>Distribution of Allele and genotype frequency of MAOA gene.</p

Association of lottery and insurance purchase with MAOA.

<p>Logit regression is used to test the effect of MAOA on lottery and insurance purchase with control variables of age, gender, student status, and education. This table reports results using both allele and genotype models for pooled, male, and female subjects. OR refers to odds ratio and CI refers to its 95% confidence interval.</p

MAOA gene, lottery, and insurance.

<p>(A). MAOA and lottery. Subjects with the high activity allele (4-repeat allele) are significantly more likely to exhibit longshot preference than subject with the low activity allele (3-repeat allele). (B). MAOA and insurance. Subjects with the low activity allele (3-repeat allele) are more likely to exhibit preference for insurance than subject with the high activity allele (4-repeat allele).</p

Plasma oxytocin and trustworthiness.

<p>(A) Scatter Plot on the relationship between plasma oxytocin and trustworthiness. (B) Histogram on the relationship between plasma oxytocin and trustworthiness.</p

Regression results for linear and nonlinear relationship between plasma oxytocin and trust.

<p>The table reports coefficient, standard error, and p values. The last row is R-squared.</p

Plasma oxytocin and trust.

<p>(A) Scatter Plot on the relationship between plasma oxytocin and trust. (B) Histogram on the relationship between plasma oxytocin and trust.</p

Differential expression of <i>GABRB2</i> isoforms in antipsychotics dosage-based SCZ subgroups.

<p>US SCZ patients were divided into a ‘High’ (>5 mg/day) antipsychotics dosage subgroup (n = 20) and a ‘Low’ (≤5 mg/day) subgroup (n = 15). The expression levels of β_2S, β_2S1, β_2S2 and β_2L in the healthy control group (white), subgroup of patients with ‘Low’ average antipsychotics dosage (light blue), or subgroup of patients with ‘High’ average antipsychotics dosage (dark blue) are shown in box-and-whisker representation with a specified percentile range of 5%–95%. For each isoform, the mean expression level in the healthy control group was employed to normalize the data for that isoform. The small square within each box indicates the mean expression level for that data group. Symbol * denotes significant difference in expression between the two line-connected groups.</p

Post-hoc analyses of genetic effects on PANSS scores, antipsychotic dosage and altruism scores.

<p>PANSS positive scores (PANSS Score) of Chinese male schizophrenics (Part A), average antipsychotics dosage, in mg fluphenazine equivalents per day, of US schizophrenics (Part B) and altruism scores of healthy Chinese subjects (Parts C) are shown. The homozygous major genotype is shown by white column, heterozygous genotype by lighter colored column, and homozygous minor genotype by darker colored column, as mean ± standard error. Symbol *denotes significant difference (<i>p</i><0.05 based on Mann-Whitney U test) between the two line-connected genotypes.</p

<i>GABRB2</i> association in PANSS score-based SCZ subgroups.

<p>The Beijing SCZ cohort (‘All’) was partitioned into ‘High score’ and ‘Low score’ subgroups by applying the K-Means clustering function to the PANSS scores for positive symptoms. The <i>p</i>-values were obtained from case-control association analysis using the likelihood ratio test. Significant <i>p</i> values (<i>p</i><0.05) that passed the global permutation test are shown in bold font. The odds ratio (OR) and its 95% confidence level (CI) were based on allele frequencies.</p

<i>GABRB2</i> association in antipsychotics dosage-based SCZ subgroups.

<p>Based on the average daily antipsychotics dosage of 5 mg fluphenazine equivalent, the US SCZ cohort (‘All’) was divided into ‘High dosage’ (>5 mg/day) and ‘Low dosage’ (≤5 mg/day) groups. The <i>p</i>-values were obtained from case-control association analysis using the likelihood ratio test. Significant <i>p</i> values (<i>p</i><0.05) that passed the global permutation test are shown in bold font. The odds ratio (OR) and its 95% confidence level (CI) were based on allele frequencies.</p