932 research outputs found
On Existence of alpha-Core Solutions for Games with Finite or Infinite Players
This gives two existence results of alpha-core solutions by introducing
P-open conditions and strong P-open conditions into games without ordered
preferences. The existence of alpha-core solutions is obtained for games with
infinite-players. Secondly, it provides a short proof of Kajii's (Journal of
Economic Theory 56, 194-205, 1992) existence theorem for alpha-core solutions,
further, the Kajii's theorem is equivalent to the Browder fixed point theorem.
In addition, the obtained existence results can include many typical results
for alpha-core solutions and some recent existence results as special cases.Comment: 10 page
The Existence and Stability of Solutions for Vector Quasiequilibrium Problems in Topological Order Spaces
In a topological sup-semilattice, we established a new existence result for vector quasiequilibrium problems. By the analysis of essential stabilities of maximal elements in a topological sup-semilattice, we prove that for solutions of each vector quasi-equilibrium problem, there exists a connected minimal essential set which can resist the perturbation of the vector quasi-equilibrium problem
CoRec: An Easy Approach for Coordination Recognition
In this paper, we observe and address the challenges of the coordination
recognition task. Most existing methods rely on syntactic parsers to identify
the coordinators in a sentence and detect the coordination boundaries. However,
state-of-the-art syntactic parsers are slow and suffer from errors, especially
for long and complicated sentences. To better solve the problems, we propose a
pipeline model COordination RECognizer (CoRec). It consists of two components:
coordinator identifier and conjunct boundary detector. The experimental results
on datasets from various domains demonstrate the effectiveness and efficiency
of the proposed method. Further experiments show that CoRec positively impacts
downstream tasks, improving the yield of state-of-the-art Open IE models.Comment: Accepted by EMNLP 2023 Main Conference (oral presentation
L1 cell adhesion molecule high expression is associated with poor prognosis in surgically resected brain metastases from lung adenocarcinoma
Objectives: Accurate prognosis assessment across the heterogeneous population of brain metastases is very important, which may facilitate clinical decision-making and appropriate stratification of future clinical trials. Previous studies have shown the L1 Cell Adhesion Molecule (L1CAM) is potentially involved in human malignancies of multiple different samples and unfavorable survival. However, no data of L1CAM are available for the brain metastases from lung adenocarcinoma, especially for the one with neurosurgical resection.
Method: The authors investigated the L1CAM expression in cranial metastatic lesions for patients with brain metastases from lung adenocarcinoma after neurosurgical resection using tissue microarrays that were obtained from the Department of Neurosurgery at the Cancer Hospital of the Chinese Academy of Medical Sciences. Furthermore, the relationship between L1CAM expression and clinic-pathological parameters, including overall survival time, was analyzed to assess the prognostic value of L1CAM.
Results: L1CAM high expression was found in 62.30% of brain metastases from lung adenocarcinoma and significantly correlated with brain metastasis number (p = 0.028) and Lung-molGPA score (p = 0.042). Moreover, L1CAM expression was an independent predictor of survival for brain metastases after neurosurgical resection in a multivariate analysis. Patients with L1CAM high expression had unfavorable overall survival time (p = 0.016). In addition, the multivariate analysis also showed age and extracranial transfer were also the independent prognostic factors for this type of patient with brain metastases.
Conclusions: A subset of brain metastases from lung adenocarcinoma aberrantly expresses L1CAM. L1CAM is a novel independent prognostic factor for brain metastasis from lung adenocarcinoma after neurosurgical resection
CoRec: An Easy Approach for Coordination Recognition
In this paper, we observe and address the challenges of the coordination recognition task. Most existing methods rely on syntactic parsers to identify the coordinators in a sentence and detect the coordination boundaries. However, state-of-the-art syntactic parsers are slow and suffer from errors, especially for long and complicated sentences. To better solve the problems, we propose a pipeline model COordination RECognizer (CoRec). It consists of two components: coordinator identifier and conjunct boundary detector. The experimental results on datasets from various domains demonstrate the effectiveness and efficiency of the proposed method. Further experiments show that CoRec positively impacts downstream tasks, improving the yield of state-of-the-art Open IE models.This proceeding is published as Qing Wang, Haojie Jia, Wenfei Song, and Qi Li. 2023. CoRec: An Easy Approach for Coordination Recognition. In Proceedings of the 2023 Conference on Empirical Methods in Natural Language Processing, pages 15112–15120, Singapore. Association for Computational Linguistics. doi:10.18653/v1/2023.emnlp-main.934
Stereoselective alkoxycarbonylation of unactivated C(sp^3)–H bonds with alkyl chloroformates via Pd(II)/Pd(IV) catalysis
Several examples on Pd-catalysed carbonylation of methyl C(sp^3)–H bonds with gaseous CO via Pd(II)/Pd(0) catalysis have been reported. However, methylene C(sp^3)–H carbonylation remains a great challenge, largely due to the lack of reactivity of C–H bonds and the difficulty in CO migratory insertion. Herein, we report the stereoselective alkoxycarbonylation of both methyl and methylene C(sp^3)–H bonds with alkyl chloroformates through a Pd(II)/Pd(IV) catalytic cycle. A broad range of aliphatic carboxamides and alkyl chloroformates are compatible with this protocol. In addition, this process is scalable and the directing group could be easily removed under mild conditions with complete retention of configuration
Flavonoids with α-glucosidase inhibitory activities and their contents in the leaves of Morus atropurpurea
BACKGROUND: This study aims to isolate the α-glucosidase inhibitory compounds from mulberry leaves (Morus atropurpurea Roxb., Moraceae) and to develop an analytical method for quantification of the compounds. METHODS: Four flavonoids, rutin (1), isoquercetin (2), kaempferol-3-O-rutinoside (3) and astragalin (4), were isolated by column chromatography from mulberry leaf water extracts (MWE). The α-glucosidase inhibitory activities of MWE and the four isolated compounds were evaluated by a microplate-based in vitro assay. The content of the isolated flavonoids in M. atropurpurea leaves purchased from different local herbal stores or collected in different locations was determined by high performance liquid chromatography. RESULTS: The four flavonoids (1–4) showed α-glucosidase inhibitory activities, with rutin (1) and astragalin (4) showing high α-glucosidase inhibitory activities (IC(50) values of 13.19 ± 1.10 and 15.82 ± 1.11 μM, respectively). The total contents of the four flavonoids were different among eight samples examined, ranging from 4.34 mg/g to 0.53 mg/g. CONCLUSIONS: The four flavonoids in M. atropurpurea leaves could inhibit α-glucosidase activity
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