Variazioni del livello marino in Sardegna durante gli ultimi millenni sulla base di indicatori geo-archeologici costieri

Nel corso degli ultimi decenni, le coste del Mediterraneo sono state oggetto di numerosi studi multidisciplinari che hanno permesso di identificare con precisione le variazioni del livello del mare nel corso dei millenni. L’archeologia, grazie alle possibilità offerte dallo studio di manufatti sommersi in prossimità delle coste (indicatori archeologici), può apportare un notevole contributo a questo tipo di problematica. In questo poster viene presentata una sintesi dei più recenti lavori geo-archeologici svolti lungo le coste della Sardegna; viene inoltre proposto un confronto tra il dato archeologico e il più recente modello teorico di previsione

Coastline and climatic changes in the Punic period (V-III century B.C.): archaeological and paleobotanical indicators (South Sardinia – West Mediterranean Sea)

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The monumental submerged Punic harbour of Malfatano and associated Piscinnì quarries: sea level changes and geoarchaeological approach

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Shorelines changes and human settlements dynamics in the Lagoon of Mistras- river Tirso coastal plane in the last 3 ky (Middle Bronze-High Middle Ages)

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The archaeological evidence of sea level change in the Mediterranean: guidelines and reappraisals

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Archaeological remains as sea level change markers: a review

The Mediterranean Sea constitutes a unique basin from an historical and archaeological point of view, as it has been a privileged way of communication for thousands of years for the people that dwelled on its shores. Their passage has left many traces on the seabeds in the areas where the ancient commercial routes passed, and remains of structures where moorings, havens or dwellings existed. Some of these structures, nowadays submerged, offer interesting indications aiding the reconstruction of the ancient coastlines. This contribution aims to examine recent work in coastal geo-archaeology, targeting both (1) gathering and discussion of the data, particularly those pertaining to the Italian coasts; and (2) commentary on the methodological debate and verification of the possibility of a protocol that may contain unequivocal referring elements. To investigate the archaeological evidence currently underwater because of the relative sea level variations (harbour infrastructures, fishponds, villae maritimae, caves – nymphaei, private or public buildings or town quarters, pre- and protohistorical villages, quarries, caves, etc.), a clear and more coherent methodological assumption may be needed. The archaeological interpretation must initially establish the maritime and/or harbour nature and vocation of the site, determine its typology and specific usage, analyze the elements of its building techniques (that reveal themselves as meaningful markers of height or depth at the time of building) and its ‘‘functional’’ elements (the measure of the emerged part with respect to the average sea level), and point out the time of construction, its chronological range of usage/ frequentation, the dynamics of its abandonment/destruction/obliteration. The evaluation of both the height and functional depth to the mean sea level depends on the typology of the archaeological evidence, its use and the local tide amplitudes. The surface of a pier surely has a functional elevation different from that of a haulage area or a platea or a pavement

Sea level changes and past vegetation in the Punic period (5th–4th century BC): Archaeological, geomorphological and palaeobotanical indicators (South Sardinia – West Mediterranean Sea)

The ancient shorelines and main differences in the vegetational landscape of S Sardinia during the Punic period (5th–4th century BC) have been recognized by an interdisciplinary archaeological, paleobotanical and geomorphological approach. Sixteen trading amphoras and one olla of Punic manufacture brought to light during underwater exploration in Santa Gilla Lagoon (S Sardinia, W Mediterranean) provide data on relative sea level changes. The infilling mud of each retrieved amphora is representative of the ages lasting for about 200–300 years. The macro-archaebotanical contents document the use of seeds and fruits of Vitis, Sorbus, Ficus, Olea and Prunus during Punic trading and suggest the occurrence of agro-pastoral practices in the surrounding plains or the area behind the lagoon system. The palynological analysis documents the presence of holm and cork oak forests, a widespread Mediterranean forest with Juniper and Pinus, and a developed stagnant coastal system, and reveals a climate-induced past vegetation change that is likely to have been emphasized by anthropogenic pressure and agriculture activity during the 4th century BC. The GPS localization of the amphoras shows a distribution according to curved alignments that probably correspond to the shorelines (5th-4th century BC) at – 1.95 ± 10 m and −1.70 ± 10 m. Geomorphological data reveal a sea level rise of about 25 cm during a century, corresponding to 300 m of shoreline regression towards the alluvial plain. With these rapid processes of drowning of the coastal plain, the presence of Punic settlements along the lagoon borders documents the reorganization of commercial and economic activities. This shows the great adaptability of the ancient population to the sea level rise (SLR) and fast-flooding processes of the coastline in a lagoonal area vulnerable to subsidence phenomena

Sea level changes and geoarchaeology between the bay of Capo Malfatano and Piscinnì Bay (SW Sardinia) in the last 4 kys

The bay of Malfatano Cape is the berthing home to one of the most important maritime structures from the Punic-Roman times in the Mediterranean. Two opposing monumental structures have been preserved between −7 and −2 m due to rising sea level. Recent studies have identified the paleo-sea level, relating the eustatic component to the glacio-hydroisostatic deformations. This paper, through stratigraphic, palaeontological, and geochronological data, aims to trace the bay of Capo Malfatano's evolution in relation to the sea level rise during the last 4 kys. Based on data derived from geophysical surveys, paleoshore lines have been redrawn and compared with data derived from coring in the inner part of the creek. Finally, we evaluated the relationship between changes in palaeogeography and human settlements from the Bronze Age. The breakwaters have been surveyed in detail using D-GPS techniques correlated to the geodesic 0 level. Through this data, the shape of the breakwaters has been reconsidered and, consequently, the palaeo sea level has been re-evaluated

Sea-level change during the Holocene in Sardinia and in the northeastern Adriatic (central Mediterranean Sea) from archaeological and geomorphological data

We provide new data on relative sea-level change from the late Holocene for two locations in the central Mediterranean: Sardinia and NE Adriatico. They are based on precise measures of submerged archaeological and tide notch markers that are good indicators of past sea-level elevation. Twelve submerged archaeological sites were studied: six, aged between 2.5 and 1.6 ka BP, located along the Sardinia coast, and a further six, dated ∼2.0 ka BP, located along the NE Adriatic coast (Italy, Slovenia and Croatia). For Sardinia, we also use beach rock and core data that can be related to Holocene sea level. The elevations of selected significant archaeological markers were measured with respect to the present sea level, applying corrections for tide and atmospheric pressure values at the time of surveys. The interpretation of the functional heights related to sea level at the time of their construction provides data on the relative changes between land and sea; these data are compared with predictions derived from a new glacio-hydro-isostatic model associated with the Last Glacial cycle. Sardinia is tectonically relatively stable and we use the sea-level data from this island to calibrate our models for eustatic and glacio-hydro-isostatic change. The results are consistent with those from another tectonically stable site, the Versilia Plain of Italy. The northeast Adriatic (Italy, Slovenia and Croatia) is an area of subsidence and we use the calibrated model results to separate out the isostatic from the tectonic contributions. This indicates that the Adriatic coast from the Gulf of Trieste to the southern end of Istria has tectonically subsided by ∼1.5 m since Roman times

Cemiplimab in Ultra-Octogenarian Patients with Cutaneous Squamous Cell Carcinoma: The Real-Life Experience of a Tertiary Referral Center

Background: The incidence of cutaneous squamous cell carcinoma (cSCC) is rapidly increasing, paralleling the aging of the population. cSCC predominantly affects chronically sun-exposed areas, such as the head and neck region. At our tertiary center, a multidisciplinary approach to non-melanoma skin cancer is provided for locally advanced cSCC. Methods: We retrospectively revised all patients with locally advanced/metastatic cSCC treated with anti-PD1 antibody (Cemiplimab) at our Institution from January 2020 to March 2023 (minimum follow-up of 4 months on treatment). Results: Overall, we consecutively treated 20 ultra-octogenarian patients, of whom 15 were males and 5 were females (median age: 86.9 years). Despite age, a median number of concomitant drugs, and comorbidities, efficacy, and safety were superimposable with the available literature. No patients reported treatment-related adverse events of grade 3 or higher. Grade 2 adverse events were reported in 25% of patients. Overall, the response rate was 65%, with 50% partial responses and 20% long-lasting stable disease. The median duration of response was 14 months. The G8 elderly score was assessed in all patients, and the median score was 12 (range 9–14). Conclusions: Among ultra-octogenarian patients, a clinical benefit from Cemiplimab was obtained in most, including tumor shrinkage and pain relief. Cemiplimab confirmed its effectiveness in elderly patients in a real-life setting, with no new safety concerns