Regioselective iodination of aryl amines using 1,4-dibenzyl-1,4-diazoniabicyclo [2.2.2] octane dichloroiodate in solution and under solvent-free conditions

1,4-Dibenzyl-1,4-diazoniabicyclo[2.2.2]octane dichloroiodate is an efficient and regioselective reagent for iodination of aryl amines. A wide variety of aryl amines in reaction with this reagent afforded regioselectively iodinated products. The iodination reaction can be carried out in solution or under solvent-free condition at room temperature. KEY WORDS:  Regioselective iodination, Aryl amines, 1,4-Dibenzyl-1,4-diazoniabicyclo [2.2.2] octane dichloroiodate,  Solvent-free conditions Bull. Chem. Soc. Ethiop. 2015, 29(1), 157-162DOI: http://dx.doi.org/10.4314/bcse.v29i1.1

Straightforward and efficient deuteration of terminal alkynes with copper catalysis

The mild and effective preparation of deuterated organic molecules is an active area of research due to their important applications. Herein, we report an air-stable and easy to access copper(I) complex as catalyst for the deuteration of mono-substituted alkynes. Reactions were carried out in technical solvents and in the presence of air, to obtain excellent deuterium incorporation in a range of functionalised alkynes