Effect of eight weeks endurance exercise on liver enzymes in stopping drug women with methadone

Previous studies indicated that endurance exercise decreases levels of liver enzymes. The aim of this study was to determine the effect of endurance exercise on liver enzymes in eight weeks in Iranian women who are stopping the drug with methadone. sixty Iranian women prisoners including 30 cases as experimental group and 30 volunteers served as control. The mean age, height, weight, percent of BF, BMI and vo2max of experimental group was 33/8 years, 162/2 cm, 62/2 kg, 33/10, 24/22 and 16/18 ml/kg respectively. Experimental group was should run with 65%vo2max for 2 weeks (3 sessions in a week and for 25 minutes), with 65-75% vo2max for 3 weeks (3 sessions in a week for 35 minutes) and with 75-85% vo2max for 3 weeks (3 sessions in a week for 40 minutes). The blood samples were collected in amount of 5 ml 48 hours before the first session and after the last session of the protocol. Other causes of abnormal liver enzymes such as hepatitis and autoimmune disorders etc. were excluded. The level of ALT (alanine aminotransferase) between experimental group and control group in post-test was not significant. But it was significantly differenced for level of AST (aspartate aminotransferase) when we compared the groups. On the other hands, the level of ALT and AST in post-test in contrast with pre-test in experimental group was not significant. The result of this study showed that endurance exercise for eight weeks did not normalize the level of ALT and AST of the study group. Therefore more investigation such as diet habits, demographic and other risk factors is recommended for these types of patients

Retraction Note: The frequency and pattern of antibiotic resistance among Klebsiella spp. isolated from nosocomial infection in Khorramabad hospital

Report of Health Care regretfully retracts the article “The frequency and pattern of antibiotic resistance among Klebsiella spp. isolated from nosocomial infection in Khorramabad hospital” which was published in this journal in December 19, 2014. Based on recommendations from COPE, we retracted this paper, which is a duplicate and self-plagiarism of the paper entitled “Comparison frequency and Determination antibiotic resistance pattern of Klebsiella SPP. isolated from Nosocomial infection in Khorramabad Shohadaye Ashayer hospital” published in Bulletin of Environment, Pharmacology and Life Sciences (November 2014; 3(12): 149-154)

The effect of endurance training on addicted women’s level of alkaline phosphates who use methadone

Introduction: Previous studies indicated that endurance exercise is effective to decrease or increase the levels of liver enzymes. The aim of this study was to determine the effect of endurance training on alkaline phosphates (ALP) enzyme in Iranian addicted women with methadone.Methods: Thirty Iranian female addicted prisoners and thirty non-addicted encompassed the sampling. The mean of age, height, weight, %BF, body mass index (BMI), and VO2max of experimental group was 33.8 years, 162.2 cm, 62.2 kg, 33.10, 24.22 kg/m2 and 16.18 ml/kg respectively. The case group was supposed to run with 65% HRmax for 2 weeks (3 sessions in a week and for 25 minutes), 65%-75% HRmax for 3 weeks (3 sessions in a week for 35 minutes) and 75%-85% HRmax for 3 weeks (3 sessions in a week for 40 minutes). The blood samples were collected in amount of 5 ml 48 hours before the first session and after the last session of the protocol. The history of heart and liver diseases or hepatitis was not reported in case group.Results: The level of ALP between case and control group in post-test was not significant. The level of ALP in post-test in contrast with pre-test in both groups was increased but this was not statistically significant in case group (P > 0.05).Conclusion: According to the results, the level of ALP in post-test in experimental group did not change after endurance training. Therefore, the investigation of other factors such as having suitable diet habits, quitting smoking, increasing the period of training is recommended for these types of addicts