Infertility in iranian traditional medicine from Hakim Mohammad Azam Khan point of view

Introduction: Fertility and having healthy child is one of the valuable indexes in people's health. Incidence of infertility in the world has a treatment economic load and also causes significant psychiatric complications for the infertile couples and threats the health of family. Given the importance of the issue, attention to complementary medicine and use of Iranian traditional medicine can be useful and helpful. This study was performed with aim to evaluate the causes of infertility from Iranian traditional Medicine (ITM) point of view according to the valuable Exir book of Hakim Mohammad Azam Khan. Methods: This study was performed as library based on reference availabe and reliable books of traditional medicine such as law in medicine, store of Kharazmshahi, Aghili's Kholasah al-Hekmah and Moalejat with a focus on Azam Exir, and finally, what Hakim Azam Khan explained about the causes of infertility was stated. Results: Iranian medicine Hokama have suggested various reasons as the causes of infertility in men and women, separately, and stated different treatment methods such as single plants, combined drugs and method performed manually including bloodletting, cupping, and massage, and at the end of the treatment method in food section explained the type of food that is useful for disease. They divided causes of infertility into two groups of male and female factors and emphasized on the existence of semen in men and women and the role of each one in fertility. Sufficient production of semen in males and ovum in females depends on the health of body's main and vital members (including the heart, brain and liver). They reported fertility was possible through the health of genital system and production of reproductive semen in both and simultaneous orgasm of man and woman when having sex. Conclusion: According to the careful viewpoint of Hakim Azam Khan in explaining the causes of infertility and accurately classifying them, as well as description of how to diagnose and treatment courses of each of the infertility causes, it seems that today by relying on their views on empirical research, we can achieve more effective treatments for infertility. © 2015 - Journal Management System

Effects of different doses of hyaloronan on human sperm motility, vitality and morphology

Important aspect of sperm function such as motility and capacitation appear to be mediated at least partially though hyaloronic acid (HA). Present study investigated effects of different doses of HA on sperm motility and vitality in human. Sperm was obtained from 20 male from IVF clinic in Imam Khomeini Hospital. Sperm motility and vitality in human semen was analyzed according to WHO criteria before and 4 hours after treatment with different doses of HA (0.750, 1000 and 1250 μg/ml). The results showed that in 1000 μg/ml the percent of stage 3 and 4 increased compare to control group. Percent of stage 1 and 2 decreased in group with 1000 μg/ml HA, there was an increase in the percentage of stage 3 and 4 and decrease in percentage of stage 1 and 2 compare to control. In the group treated with 1250 μg/ml stage 1 and 2 increased while stage 3 and 4 decreased. Vitality in all groups decreased except of the group treated with 1000 μg/ml HA. The group with 1250 μg/ml showed significantly decrease in vitality compare to fresh group (P < 0.05). The present study showed that the effects of HA on sperm motility and vitality is dose dependant and 1000 μg/ml HA had the effective role on sperm parameters. © 2009 Tehran University of Medical Sciences. All rights reserved

Knowledge, perceptions and myths regarding infertility among selected adult population in Pakistan: a cross-sectional study

<p>Abstract</p> <p>Background</p> <p>The reported prevalence of infertility in Pakistan is approximately 22% with 4% primary and 18% secondary infertility. Infertility is not only a medical but also a social problem in our society as cultural customs and perceived religious dictums may equate infertility with failure on a personal, interpersonal, or social level. It is imperative that people have adequate knowledge about infertility so couples can seek timely medical care and misconceptions can be rectified.</p> <p>We aim to assess the knowledge, perception and myths regarding infertility and suggest ways to improve it.</p> <p>Methods</p> <p>A cross-sectional survey was carried out by interviewing a sample of 447 adults who were accompanying the patients at two tertiary care hospitals in Karachi, Pakistan. They were interviewed one-on-one with the help of a pretested questionnaire drafted by the team after a thorough literature review and in consultation with infertility specialists.</p> <p>Results</p> <p>The correct knowledge of infertility was found to be limited amongst the participants. Only 25% correctly identified when infertility is pathological and only 46% knew about the fertile period in women's cycle. People are misinformed that use of IUCD (53%) and OCPs (61%) may cause infertility. Beliefs in evil forces and supernatural powers as a cause of infertility are still prevalent especially amongst people with lower level of education. Seeking alternative treatment for infertility remains a popular option for 28% of the participant as a primary preference and 75% as a secondary preference. IVF remains an unfamiliar (78%) and an unacceptable option (55%).</p> <p>Conclusions</p> <p>Knowledge about infertility is limited in the population and a lot of misconceptions and myths are prevalent in the society. Alternative medicine is a popular option for seeking infertility treatment. The cultural and religious perspective about assisted reproductive technologies is unclear, which has resulted in its reduced acceptability.</p

Effect of Metformin on Miscarriage in Pregnant Patients with Polycystic Ovary Syndrome

ABSTRACT Background: This study was performed with the aim of evaluating the effect of metformin in reducing miscarriage when continued until the end of the first trimester of pregnancy in patients with polycystic ovary syndrome (PCOS) and infertility. Subjects and Method: From January 2004 to December 2005, a total of 75 pregnant women with PCOS were studied in three different groups. In Group A, metformin administration (500 mg TDS) was stopped immediately after diagnosis of pregnancy (5–6 weeks gestation), in Group B, metformin was administered until the end of 8 weeks gestation and in Group C until the end of 12 weeks gestation. The results of this study were then assessed using chi-square (McNemar’s, ANOVA Kruskal Wallis and logistic regression tests). Results: There was a significant statistical difference between previous and current miscarriage in the current pregnancy with a decline in Group B from 40% to 8% and in group C from 32% to 4%. In spite of the reduced rate of miscarriage seen in Group A, from 20% to 4%, this difference was not statistically significant. Fetal anomalies were absent in all three groups. Conclusion: According to the current findings, it seems that continuing metformin during the first trimester of pregnancy has beneficial effects in patients with PCOS