Characterization of bone marrow-derived mesenchymal stem cells.

(A) Phase contrast images showing the morphology of BM-MSCs cultured at the third passage. (B) Flow cytometric analysis of cell-surface markers of BM-MSCs at passage 3. (Bar, 100 μm).</p

The impact of BM-MSCs on the behavioral alternation induced by rotenone in rats.

(A) Rotarod test scores. (B-E) Open field test, measuring different parameters as indicated above the graphs. (ANOVA, n = 6, p < 0.05, Different letters indicate statistically significant differences).</p

Mesenchymal stem cell administration affects the levels of proinflammatory cytokines.

The levels of IL-6 for groups with the ordinary course of inflammation and inflammation on the background of MSCs. (ANOVA, n = 4, p < 0.05, Different letters indicate statistically significant differences).</p

The effect of stem cell administration on l-DOPA and dopamine levels in brain tissue of animals.

(ANOVA, n = 4, p < 0.05, Different letters indicate statistically significant differences).</p

The impact of stem cell administration on the oxidative stress level in brain tissue.

(ANOVA, n = 4, p < 0.05, Different letters indicate statistically significant differences).</p

The attached supporting file contains the raw data sets regarding the neurochemical measurements and the behavioral tests.

The attached supporting file contains the raw data sets regarding the neurochemical measurements and the behavioral tests.</p

Representative images of brain sections showing the histological architecture of SN and ST in each group of animals.

Representative images of brain sections showing the histological architecture of SN and ST in each group of animals.</p

Representative images from brain sections of each group of animals showing immunohistochemistry of endogenous α-Synclein, tyrosine hydroxylase, and Dopa decarboxylase in the Substania Nigra and Striatum.

Representative images from brain sections of each group of animals showing immunohistochemistry of endogenous α-Synclein, tyrosine hydroxylase, and Dopa decarboxylase in the Substania Nigra and Striatum.</p

Representative images of each group of animals showing immunohistochemistry of endogenous α-Synclein expression in the Substania Nigra and Striatum.

Representative images of each group of animals showing immunohistochemistry of endogenous α-Synclein expression in the Substania Nigra and Striatum.</p