Snow accumulation, melt, mass loss, and the near-surface ice temperature structure of Irenebreen, Svalbard

AbstractThis study examines the mass balance, accumulation, melt, and near-surface ice thermal structure of Irenebreen, a 4.1 km2 glacier located in northwest Spitsbergen, Svalbard. Traditional glaciological mass balance measurements by stake readings and snow surveying have been conducted annually at the glacier since 2002, yielding a mean annual net mass balance of −65 cm w.e. for the period 2002–2009. In 2009, the annual mass balance of Irenebreen was −63 cm w.e. despite above-average snow accumulation in winter. The near-surface ice temperature in the accumulation area was investigated with automatic borehole thermistors. The mean annual surface ice temperatures (September–August) of the accumulation area were −3.7 °C at 1 m depth and −3.3 °C at 10 m depth. Irenebreen is potentially polythermal, with cold ice and a temperate surface layer during summer. This temperate surface layer is influenced by seasonal changes in temperature. In winter, the temperature of all the ice is below the melting point and temperate layers are probably present in basal sections of the glacier. This supposition is supported by the presence of icings in the forefield of Irenebreen

Ultrafast Optical Excitation of a Persistent Surface-State Population in the Topological Insulator Bi2Se3

Using femtosecond time- and angle- resolved photoemission spectroscopy, we investigated the nonequilibrium dynamics of the topological insulator Bi2Se3. We studied p-type Bi2Se3, in which the metallic Dirac surface state and bulk conduction bands are unoccupied. Optical excitation leads to a meta-stable population at the bulk conduction band edge, which feeds a nonequilibrium population of the surface state persisting for >10ps. This unusually long-lived population of a metallic Dirac surface state with spin texture may present a channel in which to drive transient spin-polarized currents

Secondary structure and orientation of the pore-forming toxin lysenin in a sphingomyelin-containing membrane

AbstractLysenin is a sphingomyelin-recognizing toxin which forms stable oligomers upon membrane binding and causes cell lysis. To get insight into the mechanism of the transition of lysenin from a soluble to a membrane-bound form, surface activity of the protein and its binding to lipid membranes were studied using tensiometric measurements, Fourier-transform infrared spectroscopy (FTIR) and FTIR-linear dichroism. The results showed cooperative adsorption of recombinant lysenin-His at the argon–water interface from the water subphase which suggested self-association of lysenin-His in solution. An assembly of premature oligomers by lysenin-His in solution was confirmed by blue native gel electrophoresis. When a monolayer composed of sphingomyelin and cholesterol was present at the interface, the rate of insertion of lysenin-His into the monolayer was considerably enhanced. Analysis of FTIR spectra of soluble lysenin-His demonstrated that the protein contained 27% β-sheet, 28% aggregated β-strands, 10% α-helix, 23% turns and loops and 12% different kinds of aggregated forms. In membrane-bound lysenin-His the total content of α-helices, turns and loops, and β-structures did not change, however, the 1636cm−1 β-sheet band increased from 18% to 31% at the expense of the 1680cm−1 β-sheet structure. Spectral analysis of the amide I band showed that the α-helical component was oriented with at 41° to the normal to the membrane, indicating that this protein segment could be anchored in the hydrophobic core of the membrane

Calculation of Oil-saturated Sand Soils’ Heat Conductivity

Nowadays, there are significant heavy high-viscosity oil reserves in the Russian Federation with oil recovery coefficient not higher than 0.25-0.29 even with applying modern and efficient methods of oil fields development. Thermal methods are the most promising out of the existing ways of development, main disadvantage of which is large material costs, leading to the significant rise in the cost of extracted oil. Thus, creating more efficient thermal methods and improving the existing ones, is the task of great importance in oil production. One of the promising trends in enhancing thermal methods of oil recovery is the development of bottomhole electric steam generators. Compared to the traditional methods of thermal-steam formation treatment, which involve steam injection from surface, well electrothermal devices can reduce energy losses and improve the quality of steam injected into the formation. For successful and efficient organization of oil production and rational development of high-viscosity oil fields using well electrothermal equipment, it is necessary to take into account the pattern of heat propagation, both in the reservoir and in the surrounding space, including the top and bottom. One of the main values characterizing this process is the heat conductivity λ of oil-bearing rocks.  The article describes composition of typical oil-saturated sand soils, presents studies of heat and mass transfer in oil-saturated soils, reveals the effect of various parameters on the heat conductivity of a heterogeneous system, proposes a method for calculating the heat conductivity of oil-bearing soils by sequential reduction of a multicomponent system to a two-component system and proves the validity of the proposed approach by comparing acquired calculated dependencies and experimental data

Diverse Convergent Evidence in the Genetic Analysis of Complex Disease: Coordinating Omic, Informatic, and Experimental Evidence to Better Identify and Validate Risk Factors

In omic research, such as genome wide association studies, researchers seek to repeat their results in other datasets to reduce false positive findings and thus provide evidence for the existence of true associations. Unfortunately this standard validation approach cannot completely eliminate false positive conclusions, and it can also mask many true associations that might otherwise advance our understanding of pathology. These issues beg the question: How can we increase the amount of knowledge gained from high throughput genetic data? To address this challenge, we present an approach that complements standard statistical validation methods by drawing attention to both potential false negative and false positive conclusions, as well as providing broad information for directing future research. The Diverse Convergent Evidence approach (DiCE) we propose integrates information from multiple sources (omics, informatics, and laboratory experiments) to estimate the strength of the available corroborating evidence supporting a given association. This process is designed to yield an evidence metric that has utility when etiologic heterogeneity, variable risk factor frequencies, and a variety of observational data imperfections might lead to false conclusions. We provide proof of principle examples in which DiCE identified strong evidence for associations that have established biological importance, when standard validation methods alone did not provide support. If used as an adjunct to standard validation methods this approach can leverage multiple distinct data types to improve genetic risk factor discovery/validation, promote effective science communication, and guide future research directions

Spectroscopic evidence for topological band structure in FeTe0.55_{0.55}Se0.45_{0.45}

FeTe$_{0.55}$Se$_{0.45}$(FTS) occupies a special spot in modern condensed matter physics at the intersections of electron correlation, topology, and unconventional superconductivity. The bulk electronic structure of FTS is predicted to be topologically nontrivial thanks to the band inversion between the $d_{xz}$ and $p_z$ bands along $\Gamma$-$Z$. However, there remain debates in both the authenticity of the Dirac surface states (DSS) and the experimental deviations of band structure from the theoretical band inversion picture. Here we resolve these debates through a comprehensive ARPES investigation. We first observe a persistent DSS independent of $k_z$. Then, by comparing FTS with FeSe which has no band inversion along $\Gamma$-$Z$, we identify the spectral weight fingerprint of both the presence of the $p_z$ band and the inversion between the $d_{xz}$ and $p_z$ bands. Furthermore, we propose a reconciling band structure under the framework of a tight-binding model preserving crystal symmetry. Our results highlight the significant influence of correlation on modifying the band structure and make a strong case for the existence of topological band structure in this unconventional superconductor