Effect of <i>Xestospongia testudinaria</i> methanolic extract (100 mg/kg) and indomethacin (10 mg/kg) on paw GPX, SOD and CAT enzymes activity measured in carrageenan-induced rat hind paw edema.

<p>Data are mean ± SD (n = 6).</p><p>^a Significant versus control (P ≤ 0.05).</p><p>^b Significant versus carrageenan (P ≤ 0.05).</p><p>Effect of <i>Xestospongia testudinaria</i> methanolic extract (100 mg/kg) and indomethacin (10 mg/kg) on paw GPX, SOD and CAT enzymes activity measured in carrageenan-induced rat hind paw edema.</p

Low and magnified power of rat paw sections stained by H&E, (a) Control group, E: epidermis, D: dermis with no signs of vascular congestion or inflammatory cells (dotted square) with normal capillaries (black arrows) and connective tissue dermis (stars). (b) Carrageenan group, showing marked inflammatory infiltration in the deep dermis (D), capillary dilation and congestion with neutrophils margination prior to escape into the surrounding tissue (arrows;) (c) <i>Xestospongia testudinaria</i> methanolic extract group, showing significant decrease of the inflammatory cells in the dermis and within blood vessels. (d) Indomethacin group, showing a decrease in both inflammatory cells infiltration and vascular congestion.

<p>Low and magnified power of rat paw sections stained by H&E, (a) Control group, E: epidermis, D: dermis with no signs of vascular congestion or inflammatory cells (dotted square) with normal capillaries (black arrows) and connective tissue dermis (stars). (b) Carrageenan group, showing marked inflammatory infiltration in the deep dermis (D), capillary dilation and congestion with neutrophils margination prior to escape into the surrounding tissue (arrows;) (c) <i>Xestospongia testudinaria</i> methanolic extract group, showing significant decrease of the inflammatory cells in the dermis and within blood vessels. (d) Indomethacin group, showing a decrease in both inflammatory cells infiltration and vascular congestion.</p

Total antioxidant capacity of <i>Xestospongia testudinaria</i> methanolic extract at different concentrations in vitro.

<p>Expressed as percent inhibition toward DPPH-induced oxidative stress.</p

Chemical constituents of <i>Xestospongia testudinaria</i> methanolic extract, detected by GC-MS.

<p>Chemical constituents of <i>Xestospongia testudinaria</i> methanolic extract, detected by GC-MS.</p

Chromatogram obtained from GC-MS with the methanolic extracts of the <i>Xestospongia testudinaria</i>.

<p>Chromatogram obtained from GC-MS with the methanolic extracts of the <i>Xestospongia testudinaria</i>.</p

La Petite presse : journal quotidien... / [rédacteur en chef : Balathier Bragelonne]

03 avril 18841884/04/03 (A18,N6540)