Examining the Effects of Coping Strategies Specific to Community Violence Exposure Among African American Adolescents

Variability in exposure to community violence (ECV) and aggressive behaviors in African American youth from urban communities can be attributed to general coping, but these studies have been inconclusive. Recent qualitative research identified four types of coping that are specific to ECV; however, quantitative research is needed to understand the adaptiveness of these strategies. The current study examined the factor structure of a measure for ECV-specific coping strategies. The current study also assessed how ECV-specific coping was associated with ECV and externalizing behaviors. Data from the current study were derived from an archival dataset comprised of 594 African American adolescents. Results from a confirmatory factor analysis revealed that each subscale demonstrated a good fit with the data. Moderation analyses demonstrated that certain types of ECV-specific coping may interact with ECV and gender to protect against outcomes. Thus, one must consider their unique contexts when working with youth affected by ECV

Future Orientation as a Protective Factor for African American Adolescents Exposed to Community Violence

For African American youth disproportionately exposed to community violence and the associated risk of externalizing behaviors, developmental assets that reduce the risk for externalizing behaviors and enhance adaptive coping should be explored. In a sample of 572 African American adolescents (Mage = 15.85; SD = 1.42), the current study explored whether future orientation or gender buffered the impact of community violence exposure on externalizing behaviors. The current study also examined the interaction between future orientation, gender, and violence-specific coping strategies to determine their association with externalizing behaviors. Future orientation moderated the relationship between violence exposure and delinquent, but not aggressive, behaviors. Future orientation interacted differently with coping for males and females to predict externalizing behaviors. Research and clinical implications are discussed

A Latent Class Analysis of Community Violence Exposure and Peer Delinquency in African American Adolescents

Aims Person-based analyses have demonstrated wide variability among the levels of exposure to community violence (ECV) experienced by youth in disadvantaged communities. In addition, social network research has found that violence victimization tends to occur primarily among a small social group, demonstrating that levels of peer delinquency may be a factor that distinguishes among youth who experience high and low levels of ECV. Methods The current study utilized latent class analysis to examine profiles of ECV and peer delinquency in a sample of 618 African American adolescents (54.7% female; mean age = 15.8, SD = 1.41), and the relationship these profiles have to adaptive and maladaptive outcomes. Results Results demonstrated that levels of ECV and peer delinquency vary significantly among these youth, and profile membership predicts levels of delinquency, aggression, future orientation, and self-esteem. Conclusion Research and clinical implications are discussed

Ginger inhibits cell growth and modulates angiogenic factors in ovarian cancer cells

<p>Abstract</p> <p>Background</p> <p>Ginger (<it>Zingiber officinale </it>Rosc) is a natural dietary component with antioxidant and anticarcinogenic properties. The ginger component [6]-gingerol has been shown to exert anti-inflammatory effects through mediation of NF-κB. NF-κB can be constitutively activated in epithelial ovarian cancer cells and may contribute towards increased transcription and translation of angiogenic factors. In the present study, we investigated the effect of ginger on tumor cell growth and modulation of angiogenic factors in ovarian cancer cells <it>in vitro</it>.</p> <p>Methods</p> <p>The effect of ginger and the major ginger components on cell growth was determined in a panel of epithelial ovarian cancer cell lines. Activation of NF-κB and and production of VEGF and IL-8 was determined in the presence or absence of ginger.</p> <p>Results</p> <p>Ginger treatment of cultured ovarian cancer cells induced profound growth inhibition in all cell lines tested. We found that <it>in vitro</it>, 6-shogaol is the most active of the individual ginger components tested. Ginger treatment resulted in inhibition of NF-kB activation as well as diminished secretion of VEGF and IL-8.</p> <p>Conclusion</p> <p>Ginger inhibits growth and modulates secretion of angiogenic factors in ovarian cancer cells. The use of dietary agents such as ginger may have potential in the treatment and prevention of ovarian cancer.</p