Abandoning presumptive antimalarial treatment for febrile children aged less than five years--a case of running before we can walk?

Current guidelines recommend that all fever episodes in African children be treated presumptively with antimalarial drugs. But declining malarial transmission in parts of sub-Saharan Africa, declining proportions of fevers due to malaria, and the availability of rapid diagnostic tests mean it may be time for this policy to change. This debate examines whether enough evidence exists to support abandoning presumptive treatment and whether African health systems have the capacity to support a shift toward laboratory-confirmed rather than presumptive diagnosis and treatment of malaria in children under five

Platte River: Reservation and Quantification of Federal Reserved Water Rights - Firefighting & Administrative Purposes Only

This casenote addresses a decision of the Colorado Water Court interpreting whether the federal reserved water rights doctrine protects minimum quantities of streamflow in National Forests to protect the stability of stream banks. The author argues, in part, that because the court found that the flows sought by the Forest Service were necessary to protect one of the purposes of the National Forests, the water rights were improperly denied

Tobacco Farmer Interest and Success in Income Diversification

As farm income from tobacco production has declined in recent years, there has been increasing interest in identifying alternative sources of income for tobacco farmers in the southern United States The recent termination of the tobacco quota program has accelerated the exit of tobacco farmers and has heightened concern regarding the availability of substitutes for tobacco production. In this study, we examine factors influencing tobacco farmers’ attempts to identify profitable alternatives to tobacco, their off-farm employment behavior, and changes in acres of tobacco cultivated using survey data collected from a panel of North Carolina tobacco farmers combined with market datadiversification, farm programs, farmer survey, quota buyout, tobacco, Crop Production/Industries, Farm Management, Financial Economics, C33, Q12, Q18,

Tobacco Farmer Interest and Success in Diversification

As U.S. farm income from tobacco production has declined in recent years, there has been increased interest in developing alternative sources of farm revenue to replace lost tobacco income, particularly in tobacco-dependent communities of the southeastern United States. The recent end of the tobacco quota program is expected to accelerate the exit of tobacco farmers and has heightened concern regarding the availability of profitable substitutes for tobacco. In this study, we examine the impact of farm, household, and market characteristics on tobacco farmer interest and success in on-farm and off-farm income diversification. Using survey data collected from a panel of North Carolina tobacco farmers in 1997, 1999, 2001, and 2004 combined with market data collected from secondary sources, we evaluate the influence of farmer preferences, resource endowments, market incentives, risk, and biophysical factors on tobacco farmers' attitudes regarding diversification into non-tobacco products, the extent to which they reallocated resources towards non-tobacco products, and their success in identifying profitable alternatives to tobacco production. Our research contributes empirical findings to the public dialogue concerning the ability of tobacco farmers and tobacco-dependent communities to adjust to structural changes taking place in the tobacco market.Tobacco, farm diversification, household model, quota buyout., Farm Management,

How Will Tobacco Farmers Respond to the Quota Buyout? Findings from a Survey of North Carolina Tobacco Farmers

The tobacco quota buyout is expected to have significant impacts on U.S. tobacco markets, farmers, tobacco-dependent communities, and public health. Using data from four surveys of a panel of North Carolina tobacco farmers conducted between 1997 and 2004, we investigate changing farmer attitudes towards and intentions following a quota buyout.Crop Production/Industries,

Space-time variation of malaria incidence in Yunnan province, China

BACKGROUND Understanding spatio-temporal variation in malaria incidence provides a basis for effective disease control planning and monitoring. METHODS Monthly surveillance data between 1991 and 2006 for Plasmodium vivax and Plasmodium falciparum malaria across 128 counties were assembled for Yunnan, a province of China with one of the highest burdens of malaria. County-level Bayesian Poisson regression models of incidence were constructed, with effects for rainfall, maximum temperature and temporal trend. The model also allowed for spatial variation in county-level incidence and temporal trend, and dependence between incidence in June-September and the preceding January-February. RESULTS Models revealed strong associations between malaria incidence and both rainfall and maximum temperature. There was a significant association between incidence in June-September and the preceding January-February. Raw standardised morbidity ratios showed a high incidence in some counties bordering Myanmar, Laos and Vietnam, and counties in the Red River valley. Clusters of counties in south-western and northern Yunnan were identified that had high incidence not explained by climate. The overall trend in incidence decreased, but there was significant variation between counties. CONCLUSION Dependence between incidence in summer and the preceding January-February suggests a role of intrinsic host-pathogen dynamics. Incidence during the summer peak might be predictable based on incidence in January-February, facilitating malaria control planning, scaled months in advance to the magnitude of the summer malaria burden. Heterogeneities in county-level temporal trends suggest that reductions in the burden of malaria have been unevenly distributed throughout the province.This project was supported by a University of Queensland New Research Scientist Start-Up Fund grant. RWS is a Wellcome Trust Principal Research Fellow (#079080) and receives additional support from the Wellcome Trust for the Malaria Atlas Project (MAP, http://www.map.ox.ac.uk)

Interference Mitigation for coded MB-OFDM UWB

Frequency Division Multiplexing (MB-OFDM) standard for high rate Ultra Wideband (UWB) wireless communication in the 3.1– 10.6 GHz band. The performance of MB-OFDM is impacted by interference from IEEE 802.16 WiMAX systems operating in the licensed 3.5 GHz band. Motivated by recent work showing the approximately Gaussian nature of the WiMAX interference to MB-OFDM, we propose a simple two-stage interference mitigation technique for coded MB-OFDM transmissions according to the ECMA-368 standard, consisting of interference spectrum estimation during silent periods followed by appropriate bit metric weighting during Viterbi decoding. We compare parametric and non-parametric spectrum estimation techniques for coded MB-OFDM transmissions and WiMAX interference for various scenarios of interest. The proposed two-stage interference mitigation technique is shown to be highly effective at mitigating the impact of WiMAX interference