Dynamic Moire Methods for Detection of Loosened Space Shuttle Tiles

Moire fringe methods for detecting loose space shuttle tiles were investigated with a test panel consisting of a loose tile surrounded by four securely bonded tiles. The test panel was excited from 20 to 150 Hz with in-plane sinusoidal acceleration of 2 g (peak). If the shuttle orbiter can be subjected to periodic excitation of 1 to 2 g (peak) and rigid-body periodic displacements do not mask the change in the Moire pattern due to tile looseness, then the use of projected Moire fringes to detect out-of-plane rockin appears to be the most viable indicator of tile looseness since no modifications to the tiles are required

Investigation of light source and scattering medium related to vapor-screen flow visualization in a supersonic wind tunnel

Methods for increasing the radiant in light sheets used for vapor screen set-ups were investigated. Both high-pressure mercury arc lamps and lasers were considered. Pulsed operation of the air-cooled 1-kW lamps increased the light output but decreased reliability. An ellipsoidal mirror improved the output of the air-cooled lamps by concentrating the light but increased the complexity of the housing. Water-cooled-4-kW lamps coupled with high-aperture Fresnel lenses provided reasonable improvements over the air-cooled lamps. Fanned laser beams measurements of scattered light versus dew point made in conjunction with successful attempts to control the fluid injection. A number of smoke generators are described and test results comparing smoke and vapor screens are shown. Finally, one test included a periscope system to relay the image to a camera outside the flow

Guadalupe pluton–Mariposa Formation age relationships in the southern Sierran Foothills: Onset of Mesozoic subduction in northern California?

We report a new 153 ± 2 Ma SIMS U-Pb date for zircons from the hypabyssal Guadalupe pluton which crosscuts and contact metamorphoses upper crustal Mariposa slates in the southern Sierra. A ~950 m thick section of dark metashales lies below sandstones from which clastic zircons were analyzed at 152 ± 2 Ma. Assuming a compacted depositional rate of ~120 m/Myr, accumulation of Mariposa volcanogenic sediments, which overlie previously stranded Middle Jurassic and older ophiolite + chert-argillite belts in the Sierran Foothills, began no later than ~160 Ma. Correlative Oxfordian-Kimmeridgian strata of the Galice Formation occupy a similar position in the Klamath Mountains. We speculate that the Late Jurassic was a time of transition from (1) a mid-Paleozoic–Middle Jurassic interval of mainly but not exclusively strike-slip and episodic docking of oceanic terranes; (2) to transpressive plate underflow, producing calcalkaline igneous arc rocks ± outboard blueschists at ~170–150 Ma, whose erosion promoted accumulation of the Mariposa-Galice overlap strata; (3) continued transpressive underflow attending ~200 km left-lateral displacement of the Klamath salient relative to the Sierran arc at ~150–140 Ma and development of the apparent polar wander path cusps for North and South America; and (4) then nearly orthogonal mid and Late Cretaceous convergence commencing at ~125–120 Ma, during reversal in tangential motion of the Pacific plate. After ~120 Ma, nearly head-on subduction involving minor dextral transpression gave rise to voluminous continent-building juvenile and recycled magmas of the Sierran arc, providing the erosional debris to the Great Valley fore arc and Franciscan trench

Asteroseismic Signatures of Stellar Magnetic Activity Cycles

Observations of stellar activity cycles provide an opportunity to study magnetic dynamos under many different physical conditions. Space-based asteroseismology missions will soon yield useful constraints on the interior conditions that nurture such magnetic cycles, and will be sensitive enough to detect shifts in the oscillation frequencies due to the magnetic variations. We derive a method for predicting these shifts from changes in the Mg II activity index by scaling from solar data. We demonstrate this technique on the solar-type subgiant beta Hyi, using archival International Ultraviolet Explorer spectra and two epochs of ground-based asteroseismic observations. We find qualitative evidence of the expected frequency shifts and predict the optimal timing for future asteroseismic observations of this star.Comment: 5 pages including 3 figures and 1 table, MNRAS Letters accepte

Space-time variation of malaria incidence in Yunnan province, China

BACKGROUND Understanding spatio-temporal variation in malaria incidence provides a basis for effective disease control planning and monitoring. METHODS Monthly surveillance data between 1991 and 2006 for Plasmodium vivax and Plasmodium falciparum malaria across 128 counties were assembled for Yunnan, a province of China with one of the highest burdens of malaria. County-level Bayesian Poisson regression models of incidence were constructed, with effects for rainfall, maximum temperature and temporal trend. The model also allowed for spatial variation in county-level incidence and temporal trend, and dependence between incidence in June-September and the preceding January-February. RESULTS Models revealed strong associations between malaria incidence and both rainfall and maximum temperature. There was a significant association between incidence in June-September and the preceding January-February. Raw standardised morbidity ratios showed a high incidence in some counties bordering Myanmar, Laos and Vietnam, and counties in the Red River valley. Clusters of counties in south-western and northern Yunnan were identified that had high incidence not explained by climate. The overall trend in incidence decreased, but there was significant variation between counties. CONCLUSION Dependence between incidence in summer and the preceding January-February suggests a role of intrinsic host-pathogen dynamics. Incidence during the summer peak might be predictable based on incidence in January-February, facilitating malaria control planning, scaled months in advance to the magnitude of the summer malaria burden. Heterogeneities in county-level temporal trends suggest that reductions in the burden of malaria have been unevenly distributed throughout the province.This project was supported by a University of Queensland New Research Scientist Start-Up Fund grant. RWS is a Wellcome Trust Principal Research Fellow (#079080) and receives additional support from the Wellcome Trust for the Malaria Atlas Project (MAP, http://www.map.ox.ac.uk)

Brands, costs and registration status of antimalarial drugs in the Kenyan retail sector

BACKGROUND: Although an important source of treatment for fevers, little is known about the structure of the retail sector in Africa with regard to antimalarial drugs. This study aimed to assess the range, costs, sources and registration of antimalarial drugs in the Kenyan retail sector. METHODS: In 2002, antimalarial drug registration and trade prices were established by triangulating national registration lists, government gazettes and trade price indices. Data on registration status and trade prices were compared with similar data generated through a retail audit undertaken among 880 randomly sampled retailers in four districts of Kenya. RESULTS: Two hundred and eighteen antimalarial drugs were in circulation in Kenya in 2002. These included 65 "sulfur"-pyrimethamine (sulfadoxine-pyrimethamine and sulfalene-pyrimethamine (SP), the first-line recommended drug in 2002) and 33 amodiaquine (AQ, the second-line recommended drug) preparations. Only half of SP and AQ products were registered with the Pharmacy and Poisons Board. Of SP and AQ brands at district level, 40% and 44% were officially within legal registration requirements. 29% of retailers at district level stocked SP and 95% stocked AQ. The retail price of adult doses of SP and AQ were on average 0.38 and 0.76 US dollars, 100% and 347% higher than trade prices from manufacturers and importers. Artemether-lumefantrine, the newly announced first-line recommended antimalarial drug in 2004, was found in less than 1% of all retail outlets at a median cost of 7.6 US dollars. CONCLUSION: There is a need to ensure that all antimalarial drugs are registered with the Pharmacy and Poisons Board to facilitate a more stringent post-marketing surveillance system to ensure drugs are safe and of good quality post-registration

Slotted Rotatable Target Assembley and Systematic Error Analysis for a Search for Long Range Spin Dependent Interactions from Exotic Vector Boson Exchange Using Neutron Spin Rotation

We discuss the design and construction of a novel target array of nonmagnetic test masses used in a neutron polarimetry measurement made in search for new possible exotic spin dependent neutron–atominteractions of Nature at sub-mm length scales. This target was designed to accept and efficiently transmit a transversely polarized slow neutron beam through a series of long open parallel slots bounded by flat rectangular plates. These openings possessed equal atom density gradients normal to the slots from the flat test masses with dimensions optimized to achieve maximum sensitivity to an exotic spin-dependent interaction from vector boson exchanges with ranges in the mm - μm regime. The parallel slots were oriented differently in four quadrants that can be rotated about the neutron beam axis in discrete 90°increments using a Geneva drive. The spin rotation signals from the 4 quadrants were measured using a segmented neutron ion chamber to suppress possible systematic errors from stray magnetic fields in the target region. We discuss the per-neutron sensitivity of the target to the exotic interaction, the design constraints, the potential sources of systematic errors which could be present in this design, and our estimate of the achievable sensitivity using this method

Seeing through flows in Langley's 0.3-meter Transonic Cryogenic Tunnel

Viewing problems associated with the measurement of model deformation in cryogenic wind tunnels are discussed. Tests were conducted in the Langley 0.3-Meter Transonic Cryogenic Tunnel to assess viewing capabilities thru the flow field. The effects of condensation and turbulent boundary layers are discussed and a modelling procedure for image degradation is described