The Occupational Structure of Further and Higher Education in Ireland and the Netherlands

Although most types of education give access to a range of occupations, the educational background determines to a large extent the labour market possibilities of a worker. However, since educational systems vary widely between different countries, there is a question about the specific role of each type of education in a country and the influence of the structure of the educational system as a whole on the relationship between education and the labour market. In this paper a comparison of the occupational structure of further and higher education in Ireland and the Netherlands is made. This comparison is based on a common occupational classification, which provides the possibility of measuring the extent of the occupational domains of types of education and the overlap in occupational domain of different types of education within each country and between both countries. The extent of the occupational domain and the similarities within a country provide information about aspects of the occupational structure of higher education in both countries, while the similarities between types of education in both countries make it possible to determine in a simple way the mutual position of types of education in the two countries. It is shown in the paper that since the Irish education system is more generally oriented than the Dutch system, Ireland has a broader occupational domain for similar types of further and higher education, on average, than the Netherlands. In addition the occupational domains for academics and technicians in Ireland have more overlap between different fields of study than in the Netherlands. Furthermore, despite the fact that the fraction of higher educated people in the Netherlands considerably exceeds the fraction in Ireland – which might result in some qualifications inflation – some types of education in Ireland, such as engineering and agricultural science, at higher levels seem to be closer to the Dutch intermediate vocational level than to the higher level.education, training and the labour market;

A semi-Lagrangian scheme for the game pp-Laplacian via pp-averaging

We present and analyze an approximation scheme for the two-dimensional game $p$-Laplacian in the framework of viscosity solutions. The approximation is based on a semi-Lagrangian scheme which exploits the idea of $p$-averages. We study the properties of the scheme and prove that it converges, in particular cases, to the viscosity solution of the game $p$-Laplacian. We also present a numerical implementation of the scheme for different values of $p$; the numerical tests show that the scheme is accurate.Comment: 34 pages, 3 figures. To appear on Applied Numerical Mathematic

The BIOEXPLOIT Project

The EU Framework 6 Integrated Project BIOEXPLOIT concerns the exploitation of natural plant biodiversity for the pesticide-free production of food. It focuses on the pathogens Phytophthora infestans, Septoria tritici, Blumeria graminis, Puccinia spp. and Fusarium spp. and on the crops wheat, barley, tomato and potato. The project commenced in October 2005, comprises 45 laboratories in 12 countries, and is carried out by partners from research institutes, universities, private companies and small-medium enterprises. The project has four strategic objectives covered in eight sub-projects. These objectives relate to (i) understanding the molecular components involved in durable disease resistance, (ii) exploring and exploiting the natural biodiversity in disease resistance, (iii) accelerating the introduction of marker-assisted breeding and genetic engineering in the EU plant breeding industry, and (iv) coordinating and integrating resistance breeding research, providing training in new technologies, disseminating the results, and transferring knowledge and technologies to the industry

The distribution of aneurinpyrophosphate between the nucleus and the cytoplasm of chicken erythrocytes

The nuclei of chicken erythrocytes contain about 20 times as much aneurinpyrophosphate per unit volume as the cytoplasm

The conversion of aneurin into aneurinpryrophosphate by blood corpuscles

1. The in vitro synthesis of aneurinpyrophosphate from added aneurin by the white and red cells of the blood of the rat and of man was studied. Though the synthesis is by no means negligible in human blood it is much higher in rat blood. 2. An average rat leukocyte contains about 160 times as much aneuripyrophosphate as an average rat erythrocyte. This ratio is increased to about 550 upon incubation of the blood with 1 mg aneurin per ml. 3. The synthesis in inhibited by oxalate, monoiodoacetate, fluoride and cyanide. 4. The synthesis by the red cells is preferentially inhibited by oxalate, the synthesis by the white cells by cyanide. This proves that the energy required for the synthesis of aneurinpyrophosphate from aneurin is mainly provided by glycolysis in the red cells and by respiration in the white cells. 5. Upon incubation of the blood with a small amount of aneurin a higher percentage is converted into aneurinpyrophosphate than with a large amount of aneurin. However, even from 0.1 gamma-aneurin added to 1 ml of blood only 26% is phosphorylated (from 1 mg added about 0.25% is phosphorylated). 6. During incubation of rat blood with aneurin at 39°C aneurin is not destroyed, nor are substances formed inhibiting aneurin pyrophosphate synthesis. 7. The synthesis of aneurinpyrophosphate by the erythrocytes depends upon the concentration of glucose present. It is decreased when the glucose concentration is below normal or extremely high. 8. The enzym system responsible for the synthesis of aneurinpyrophosphate from aneurin is badly damaged by incubating the blood at 39°C for some hours. 9. Attention is called to the fact that process producing energy are necessary for the conversion of a certain vitamin into its physiologically active form. As other vitamins form part of various enzymes connected with energy production insight into the interrelationship of various avitaminoses may be gained from investigations on the influence of the lack or one vitamin in the food on the conversion of another vitamin into its physiologically active form

Resonant diaphragm pressure measurement system with ZnO on Si excitation

The principle of measuring pressure by means of a resonant diaphragm has been studied. An oscillator consisting of an integrated amplifier with a piezoelectrically driven diaphragm in its feedback loop has been built. The oscillator frequency is accurately proportional to the square of the pressure in the range of 60 to 130 Torr.\ud The frequency range is 1324 to 1336 Hz (this range being limited by a spurious mode which could be suppressed by better processing) for a 25 mm diameter diaphragm made of a silicon wafer and with PZT ceramics as driver and receptor. We have made an integrated version (1 × 1 mm2) of a square resonant diaphragm pressure guage by selective etching of (1 0 0) planes with ethylenediamine. The piezoelectric driving materials was sputtered zinc oxide. A driver was deposited midway between the bending point and the point of greatest curvature.\ud A receptor was located at a symmetrical position to give a optimum transfer condition.\ud The integrated current amplifier had a low impedance differential input stage, two gain cells and a high impedance output stage. These electrical conditions ensured maximum elastic freedom of the diaphragm. A digital circuit in I2L technology has been designed and made with eight-bit parallel read out of the frequency. This circuit may be directly connected to a microprocessor. The whole system contains the sensor chip, the analog amplifier chip and the digital chip, all in compatible technology.\ud \u

How to change the oligomeric state of a circular protein assembly: switch from 11-subunit to 12-subunit TRAP suggests a general mechanism

Many critical cellular functions are performed by multisubunit circular protein oligomers whose internal geometry has evolved to meet functional requirements. The subunit number is arguably the most critical parameter of a circular protein assembly, affecting the internal and external diameters of the assembly and often impacting on the protein's function. Although accurate structural information has been obtained for several circular proteins, a lack of accurate information on alternative oligomeric states has prevented engineering such transitions. In this study we used the bacterial transcription regulator TRAP as a model system to investigate the features that define the oligomeric state of a circular protein and to question how the subunit number could be manipulated.We find that while Bacillus subtilis and Bacillus stearothermophilus TRAP form 11-subunit oligomers, the Bacillus halodurans TRAP exclusively forms 12-subunit assemblies. Significantly, the two states of TRAP are related by a simple rigid body rotation of individual subunits around inter-subunit axes. We tested if such a rotation could be induced by insertion or deletion mutations at the subunit interface. Using wild type 11-subunit TRAP, we demonstrate that removal of five C-terminal residues at the outer side of the inter-subunit axis or extension of an amino acid side chain at the opposite, inner side, increased the subunit number from 11 to 12. Our findings are supported by crystal structures of TRAP oligomers and by native mass spectrometry data.The subunit number of the TRAP oligomer can be manipulated by introducing deletion or addition mutations at the subunit interface. An analysis of available and emerging structural data on alternative oligomeric states indicates that the same principles may also apply to the subunit number of other circular assemblies suggesting that the deletion/addition approach could be used generally to engineer transitions between different oligomeric states

The optimal schedule for pulsar timing array observations

In order to maximize the sensitivity of pulsar timing arrays to a stochastic gravitational wave background, we present computational techniques to optimize observing schedules. The techniques are applicable to both single and multi-telescope experiments. The observing schedule is optimized for each telescope by adjusting the observing time allocated to each pulsar while keeping the total amount of observing time constant. The optimized schedule depends on the timing noise characteristics of each individual pulsar as well as the performance of instrumentation. Several examples are given to illustrate the effects of different types of noise. A method to select the most suitable pulsars to be included in a pulsar timing array project is also presented.Comment: 16 pages, 6 figures, accepted by MNRA