Testing use of mitochondrial COI sequences for the identification and phylogenetic analysis of New Zealand caddisflies (Trichoptera)

We tested the hypothesis that cytochrome c oxidase subunit 1 (COI) sequences would successfully discriminate recognised species of New Zealand caddisflies. We further examined whether phylogenetic analyses, based on the COI locus, could recover currently recognised superfamilies and suborders. COI sequences were obtained from 105 individuals representing 61 species and all 16 families of Trichoptera known from New Zealand. No sequence sharing was observed between members of different species, and congeneric species showed from 2.3 to 19.5% divergence. Sequence divergence among members of a species was typically low (mean = 0.7%; range 0.0–8.5%), but two species showed intraspecific divergences in excess of 2%. Phylogenetic reconstructions based on COI were largely congruent with previous conclusions based on morphology, although the sequence data did not support placement of the purse-cased caddisflies (Hydroptilidae) within the uncased caddisflies, and, in particular, the Rhyacophiloidea. We conclude that sequence variation in the COI gene locus is an effective tool for the identification of New Zealand caddisfly species, and can provide preliminary phylogenetic inferences. Further research is needed to ascertain the significance of the few instances of high intra-specific divergence and to determine if any instances of sequence sharing will be detected with larger sample sizes

Polychromatic flow cytometry is more sensitive than microscopy in detecting small monoclonal plasma cell populations

Background There is an emerging role for flow cytometry (FC) in the assessment of small populations of plasma cells (PC). However, FC's utility has been questioned due to consistent underestimation of the percentage of PC compared to microscopy. Methods A retrospective study was performed on bone marrow samples analysed by 8-colour FC. Plasma cell populations were classified as polyclonal or monoclonal based on FC analysis. FC findings were compared with microscopy of aspirates, histology and immunohistochemistry of trephine biopsies, and immunofixation (IFX) of serum and/or urine. Results FC underestimated PC compared to aspirate and trephine microscopy. The 10% diagnostic cutoff for MM on aspirate microscopy corresponded to a 3.5% cutoff on FC. Abnormal plasma cell morphology by aspirate microscopy and clonality by FC correlated in 229 of 294 cases (78%). However, in 50 cases, FC demonstrated a monoclonal population but microscopy reported no abnormality. In 15 cases, abnormalities were reported by microscopy but not by FC. Clonality assessment by trephine microscopy and FC agreed in 251/280 cases (90%), but all 29 discordant cases were monoclonal by FC and not monoclonal by microscopy. These cases had fewer PC and proportionally more polyclonal PC, and when IFX detected a paraprotein, it had the same light chain as in the PC determined by FC. Conclusions FC was more sensitive in detecting monoclonal populations that were small or accompanied by polyclonal PC. This study supports the inclusion of FC in the evaluation of PC, especially in the assessment of small population

Experimental Evidence for Quantum Structure in Cognition

We proof a theorem that shows that a collection of experimental data of membership weights of items with respect to a pair of concepts and its conjunction cannot be modeled within a classical measure theoretic weight structure in case the experimental data contain the effect called overextension. Since the effect of overextension, analogue to the well-known guppy effect for concept combinations, is abundant in all experiments testing weights of items with respect to pairs of concepts and their conjunctions, our theorem constitutes a no-go theorem for classical measure structure for common data of membership weights of items with respect to concepts and their combinations. We put forward a simple geometric criterion that reveals the non classicality of the membership weight structure and use experimentally measured membership weights estimated by subjects in experiments to illustrate our geometrical criterion. The violation of the classical weight structure is similar to the violation of the well-known Bell inequalities studied in quantum mechanics, and hence suggests that the quantum formalism and hence the modeling by quantum membership weights can accomplish what classical membership weights cannot do.Comment: 12 pages, 3 figure

Solitary wave solution to the generalized nonlinear Schrodinger equation for dispersive permittivity and permeability

We present a solitary wave solution of the generalized nonlinear Schrodinger equation for dispersive permittivity and permeability using a scaling transformation and coupled amplitude-phase formulation. We have considered the third-order dispersion effect (TOD) into our model and show that soliton shift may be suppressed in a negative index material by a judicious choice of the TOD and self-steepening parameter.Comment: 6 page

Spin Textures of Polariton Condensates in a Tunable Microcavity with Strong Spin-Orbit Interaction

We report an extended family of spin textures in coexisting modes of zero-dimensional polariton condensates spatially confined in tunable open microcavity structures. The coupling between photon spin and angular momentum, which is enhanced in the open cavity structures, leads to new eigenstates of the polariton condensates carrying quantised spin vortices. Depending on the strength and anisotropy of the cavity confinement potential and the strength of the spin-orbit coupling, which can be tuned via the excitonic/photonic fractions, the condensate emissions exhibit either spin-vortex-like patterns or linear polarization, in good agreement with theoretical modelling

Classical Logical versus Quantum Conceptual Thought: Examples in Economics, Decision theory and Concept Theory

Inspired by a quantum mechanical formalism to model concepts and their disjunctions and conjunctions, we put forward in this paper a specific hypothesis. Namely that within human thought two superposed layers can be distinguished: (i) a layer given form by an underlying classical deterministic process, incorporating essentially logical thought and its indeterministic version modeled by classical probability theory; (ii) a layer given form under influence of the totality of the surrounding conceptual landscape, where the different concepts figure as individual entities rather than (logical) combinations of others, with measurable quantities such as 'typicality', 'membership', 'representativeness', 'similarity', 'applicability', 'preference' or 'utility' carrying the influences. We call the process in this second layer 'quantum conceptual thought', which is indeterministic in essence, and contains holistic aspects, but is equally well, although very differently, organized than logical thought. A substantial part of the 'quantum conceptual thought process' can be modeled by quantum mechanical probabilistic and mathematical structures. We consider examples of three specific domains of research where the effects of the presence of quantum conceptual thought and its deviations from classical logical thought have been noticed and studied, i.e. economics, decision theory, and concept theories and which provide experimental evidence for our hypothesis.Comment: 14 page