867 research outputs found

    Shifting Images: Film and Historical Legacy of Malcolm X, 1959-2021

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    Malcolm X, born Malcolm Little and died el-Hajj Malik el-Shabazz, left an indelible mark on the American consciousness. Between 1952 and 1964, Malcolm X earned renown as a minister for the Nation of Islam under the guidance of the Honorable Elijah Muhammad. The first film appearance of Malcolm X himself was in the 1959 documentary The Hate That Hate Produced, a film that sent both Malcolm and the Nation of Islam onto the national, and eventually international, stage. The next attempt to immortalize the man in film would be after his death, in 1972’s Malcolm X, a documentary based on The Autobiography of Malcolm X. The efforts of that film would bleed directly into 1992’s Malcolm X, a dramatization of the same autobiography. For nearly thirty years there was a dearth of films about the man until 2020’s One Night in Miami, a fictionalization of a real night experienced by Malcolm X. By looking at the historical memory of Malcolm X through the framework of film; including what information the filmmakers used to create their works, what messages they portray through cinematic language and critical and audience reviews; this work seeks to trace the shifting film memory of Malcolm X

    A study of two stochastic search methods for structural control

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    Abstract: Many engineering tasks involve the search for good solutions among many possibilities. In most cases, tasks are too complex to be modeled completely and their solution spaces often contain local minima. Therefore, classical optimization techniques cannot, in general, be applied effectively. This paper studies two stochastic search methods, one well-established �simulated annealing � and one recently developed �probabilistic global search Lausanne�, applied to structural shape control. Search results are applied to control the quasistatic displacement of a tensegrity structure with multiple objectives and interdependent actuator effects. The best method depends on the accuracy related to requirements defined by the objective function and the maximum number of evaluations that are allowed

    Abnormal T Cell Frequencies, Including Cytomegalovirus-Associated Expansions, Distinguish Seroconverted Subjects at Risk for Type 1 Diabetes

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    We analyzed T cell subsets from cryopreserved PBMC obtained from the TrialNet Pathway to Prevention archives. We compared subjects who had previously seroconverted for one or more autoantibodies with non-seroconverted, autoantibody negative individuals. We observed a reduced frequency of MAIT cells among seroconverted subjects. Seroconverted subjects also possessed decreased frequencies of CCR4-expressing CD4 T cells, including a regulatory-like subset. Interestingly, we found an elevation of CD57+, CD28-, CD127-, CD27- CD8 T cells (SLEC) among seroconverted subjects that was most pronounced among those that progressed to disease. The frequency of these SLEC was strongly correlated with CMV IgG abundance among seroconverted subjects, associated with IA-2 levels, and most elevated among CMV+ seroconverted subjects who progressed to disease. Combined, our data indicate discrete, yet profound T cell alterations are associated with islet autoimmunity among at-risk subjects

    Health and Quality of Life among People with Intellectual and Developmental Disabilities and Direct Support Professionals during the early United States COVID-19 Pandemic

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    People with intellectual and developmental disabilities (IDD) and the direct support professionals (DSPs) who support them have faced unique risks to their health and quality of life (QoL) throughout the COVID-19 pandemic. We sought to understand how COVID-19 has influenced QoL and overall well-being among these populations. We conducted a Rapid Qualitative Inquiry study with a sample of people with IDD and DSPs (n = 18) to gain deeper perspectives about QoL and well-being during the pandemic. Participants described that changes in QoL were typically negative and influenced primarily by reduced socialization and impacts on health and independence; however, participants also described the ways their interactions and mutual support for each other helped to preserve some aspects of QoL. Participants described how racism and publicized acts of racial violence contributed to their COVID-19 experiences, and offered descriptions of resources they benefited from, and those they lacked, during this time. Study findings have the potential to inform the development of policies and best practices that support people with IDD and DSPs during and following similar infectious disease emergencies

    Ruptured heterotopic pregnancy presenting as hemorrhagic shock

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    Background: Heterotopic pregnancy is a rare event consisting of simultaneous intrauterine and extrauterine pregnancies. If undiagnosed, it is probable the patient will present to an Emergency Department and require emergent care. Case Report: A 25 year-old woman arrived at the Emergency Department at 14 weeks gestation reporting sharp abdominal cramping and pelvic pain with a history of current tobacco use. Trans-abdominal ultrasound revealed a viable intrauterine pregnancy consistent with 14 weeks, closed cervix with free fluid noted in pelvis, and no evidence of ovarian torsion. Over the next three hours, the patient’s condition deteriorated and hemoglobin levels dropped. The surgeon on call was consulted and suspected ruptured hepatic adenoma versus hepatic hemangioma versus visceral aneurysm. A laparotomy was emergently performed with supraceliac control of aorta to permit resuscitation, and the right and left upper quadrants of the abdominal cavity were investigated without discovery of bleeding source. Further investigation revealed ruptured left tubal ectopic pregnancy and a partial salpingectomy was performed. Conclusions: This case serves as a clinical reminder that while heterotopic pregnancy is thought to be rare, when a patient presents with known intrauterine pregnancy and abdominal pain, heterotopic pregnancy should be included in the differential diagnosis. More common use of assisted reproductive technology may increase the incidence of heterotopic pregnancies, making familiarity with the signs, symptoms, and risk factors for this condition important
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