701 research outputs found

    Cross-lingual Question Answering with QED

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    We present improvements and modifications of the QED open-domain question answering system developed for TREC-2003 to make it cross-lingual for participation in the CrossLinguistic Evaluation Forum (CLEF) Question Answering Track 2004 for the source languages French and German and the target language English. We use rule-based question translation extended with surface pattern-oriented pre- and post-processing rules for question reformulation to create and English query from its French or German original. Our system uses deep processing for the question and answers, which requires efficient and radical prior search space pruning. For answering factoid questions, we report an accuracy of 16% (German to English) and 20% (French to English), respectively

    Synaptophysin sustains presynaptic performance by preserving vesicular synaptobrevin-II levels

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    The two most abundant molecules on synaptic vesicles (SVs) are synaptophysin and synaptobrevin-II (sybII). SybII is essential for SV fusion, whereas synaptophysin is proposed to control the trafficking of sybII after SV fusion and its retrieval during endocytosis. Despite controlling key aspects of sybII packaging into SVs, the absence of synaptophysin results in negligible effects on neurotransmission. We hypothesised that this apparent absence of effect may be because of the abundance of sybII on SVs, with the impact of inefficient sybII retrieval only revealed during periods of repeated SV turnover. To test this hypothesis, we subjected primary cultures of synaptophysin knockout neurons to repeated trains of neuronal activity, while monitoring SV fusion events and levels of vesicular sybII. We identified a significant decrease in both the number of SV fusion events (monitored using the genetically encoded reporter vesicular glutamate transporter-pHluorin) and vesicular sybII levels (via both immunofluorescence and Western blotting) using this protocol. This revealed that synaptophysin is essential to sustain both parameters during periods of repetitive SV turnover. This was confirmed by the rescue of presynaptic performance by the expression of exogenous synaptophysin. Importantly, the expression of exogenous sybII also fully restored SV fusion events in synaptophysin knockout neurons. The ability of additional copies of sybII to fully rescue presynaptic performance in these knockout neurons suggests that the principal role of synaptophysin is to mediate the efficient retrieval of sybII to sustain neurotransmitter release

    Initial determination of the spins of the gluino and squarks at LHC

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    In principle particle spins can be measured from their production cross sections once their mass is approximately known. The method works in practice because spins are quantized and cross sections depend strongly on spins. It can be used to determine, for example, the spin of the top quark. Direct application of this method to supersymmetric theories will have to overcome the challenge of measuring mass at the LHC, which could require high statistics. In this article, we propose a method of measuring the spins of the colored superpatners by combining rate information for several channels and a set of kinematical variables, without directly measuring their masses. We argue that such a method could lead to an early determination of the spin of gluino and squarks. This method can be applied to the measurement of spin of other new physics particles and more general scenarios.Comment: 23 pages, 8 figures, minor change

    Geometric representation of interval exchange maps over algebraic number fields

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    We consider the restriction of interval exchange transformations to algebraic number fields, which leads to maps on lattices. We characterize renormalizability arithmetically, and study its relationships with a geometrical quantity that we call the drift vector. We exhibit some examples of renormalizable interval exchange maps with zero and non-zero drift vector, and carry out some investigations of their properties. In particular, we look for evidence of the finite decomposition property: each lattice is the union of finitely many orbits.Comment: 34 pages, 8 postscript figure

    Minimal Universal Extra Dimensions in CalcHEP/CompHEP

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    We present an implementation of the model of minimal universal extra dimensions (MUED) in CalcHEP/CompHEP. We include all level-1 and level-2 Kaluza-Klein (KK) particles outside the Higgs sector. The mass spectrum is automatically calculated at one loop in terms of the two input parameters in MUED: the radius of the extra dimension and the cut-off scale of the model. We implement both the KK number conserving and the KK number violating interactions of the KK particles. We also account for the proper running of the gauge coupling constants above the electroweak scale. The implementation has been extensively cross-checked against known analytical results in the literature and numerical results from other programs. Our files are publicly available and can be used to perform various automated calculations within the MUED model.Comment: 32 pages, 4 figures, 6 tables, invited contribution for New Journal of Physics Focus Issue on 'Extra Space Dimensions', the model file can be downloaded from http://home.fnal.gov/~kckong/mued

    Podoconiosis and soil-transmitted helminths (STHs): double burden of neglected tropical diseases in Wolaita zone, rural southern Ethiopia

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    Background Both podoconiosis and soil-transmitted helminth (STH) infections occur among barefoot people in areas of extreme poverty; however, their co-morbidity has not previously been investigated. We explored the overlap of STH infection and podoconiosis in Southern Ethiopia and quantified their separate and combined effects on prevalent anemia and hemoglobin levels in podoconiosis patients and health controls from the same area. Methods and Principal Findings A two-part comparative cross-sectional study was conducted in Wolaita zone, southern Ethiopia. Data were collected from adult patients presenting with clinically confirmed podoconiosis, and unmatched adult neighborhood controls living in the same administrative area. Information on demographic and selected lifestyle factors was collected using interviewer-administered questionnaires. Stool samples were collected and examined qualitatively using the modified formalin-ether sedimentation method. Hemoglobin level was determined using two different methods: hemoglobinometer and automated hematology analyzer. A total of 913 study subjects (677 podoconiosis patients and 236 controls) participated. The prevalence of any STH infection was 47.6% among patients and 33.1% among controls (p<0.001). The prevalence of both hookworm and Trichuris trichiura infections was significantly higher in podoconiosis patients than in controls (AOR 1.74, 95% CI 1.25 to2.42, AOR 6.53, 95% CI 2.34 to 18.22, respectively). Not wearing shoes and being a farmer remained significant independent predictors of infection with any STH. There was a significant interaction between STH infection and podoconiosis on reduction of hemoglobin level (interaction p value = 0.002). Conclusions Prevalence of any STH and hookworm infection was higher among podoconiosis patients than among controls. A significant reduction in hemoglobin level was observed among podoconiosis patients co-infected with hookworm and ‘non-hookworm STH’. Promotion of consistent shoe-wearing practices may have double advantages in controlling both podoconiosis and hookworm infection in the study area

    A striking correspondence between the dynamics generated by the vector fields and by the scalar parabolic equations

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    The purpose of this paper is to enhance a correspondence between the dynamics of the differential equations y˙(t)=g(y(t))\dot y(t)=g(y(t)) on Rd\mathbb{R}^d and those of the parabolic equations u˙=Δu+f(x,u,u)\dot u=\Delta u +f(x,u,\nabla u) on a bounded domain Ω\Omega. We give details on the similarities of these dynamics in the cases d=1d=1, d=2d=2 and d3d\geq 3 and in the corresponding cases Ω=(0,1)\Omega=(0,1), Ω=T1\Omega=\mathbb{T}^1 and dim(Ω\Omega)2\geq 2 respectively. In addition to the beauty of such a correspondence, this could serve as a guideline for future research on the dynamics of parabolic equations
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