4 research outputs found
The impact of passive smoking on asthma control in children
Izloženost duhanskom dimu je riziÄni Äimbenik za nastanak ili pogorÅ”anje mnogih poremeÄaja, ukljuÄujuÄi astmu. Cilj ovog istraživanja
je ustvrditi pogorŔava li pasivno puŔenje u djece vrijednosti spirometrijskih i alergijskih parametara mjerenih iz krvi. Provedeno
je retrospektivno istraživanje parova u razdoblju od 2011. do 2013. godine, u AlergoloÅ”koj ambulanti Klinike za djeÄje bolesti KBC-a
Split. U istraživanje je ukljuÄeno 60-ero djece u dobi od 5 do 18 godina s dijagnozom astme (postavljenom prema GINA smjernicama
iz 2006. godine), koje smo podijelili u dvije skupine: 36-ero djece Äiji su ukuÄani puÅ”ili i 24-ero kojoj su ukuÄani bili nepuÅ”aÄi. Analizi rani
su parametri krivulje protok-volumen: PEF, FVC, FEV1, FEF25, FEF50 i FEF75 prije i poslije obavljenog bronhodilatacijskog testa sa dva
udaha salbutamol (Ventolin) spreja, 100 Ī¼g po udahu; alergijski markeri iz krvi: ukupna konc. IgE-a u serumu, apsolutni i relativni
broj eozinofi la u krvi te broj eozinoifi la u brisu nosa. Podatci su prikupljeni od roditelja putem upitnika te uvidom u elektroniÄku medicinsku
dokumentaciju. Nije dokazana statistiÄki znaÄajna razlika izmeÄu skupine djece izložene pasivnom puÅ”enju i kontrolne
skupine u promatranim vrijednostima. Broj puÅ”aÄa u kuÄanstvu takoÄer nije pokazao znaÄajan utjecaj na spomenute vrijednosti.
PronaÄena je znaÄajna razlika u vrijednosti ECP-a izmeÄu skupine djece Äiji su ukuÄani puÅ”ili u domu i one kojoj su ukuÄani puÅ”ili
izvan njega (P = 0,009). Broj na dan popuÅ”enih cigareta u domu statistiÄki znaÄajno korelira s relativnim brojem eozinofi la u krvi
(P = 0,048). Pasivno puÅ”enje nije se pokazalo povezanim s brojem alergena na koje je dijete alergiÄno.The aim of this study was to determine whether passive smoking aff ects spirometry parameters and allergy blood test results in
children. A retrospective case control study was conducted in the allergy clinic of the Department of Pediatrics, Split University Hospital
Center, during the 2011-2013 period. The study included 60 children with asthma, aged between 5 and 18, that presented to the
allergy clinic with their parents. Children were divided into two groups: 36 children whose household members smoked and 24
children whose household members did not smoke. We analyzed spirometric parameters before and after bronchodilatator test
with two salbutamol 100 micrograms/dose inhalations (Ventolin); allergy blood tests; and eosinophil count in nasal swab. All necessary
data were collected by a questionnaire fi lled out by the parents and accessing the patient electronic medical records. There was
no statistically signifi cant diff erence in spirometry parameters, eosinophil count in nasal swab and allergy blood tests between the
group of children whose household members smoked and the control group. The number of household smokers showed no signifi -
cant eff ect on the aforementioned values either. ECP concentration showed a statistically signifi cant diff erence according to the
household members smoking within and outside the household (P=0.009). A positive correlation was found between the number of
daily smoked cigarettes and relative eosinophil count (P=0.048). We found no connection between passive smoking and the number
of allergens in children
Patau sindrom
Genetic syndromes caused by chromosomal aberrations involve a recognizable pattern of multiple congenital anomalies with increased neonatal and infant mortality, making care challenging for the family, primary care practitioners, and specialists. About 28% of children born with trisomy 13 die during the fi rst week of life. The median life expectancy is about 2.5 days. We present a 12-year-old girl, the longest living patient with Patau syndrome in Croatia, followed-up from the birth until the age of 12 years. The conventional nonintervention approach has been revised and we suggest changing the traditional view of the condition.Genetski sindromi uzrokovani kromosomnim aberacijama ukljuÄuju prepoznatljivi obrazac viÅ”estrukih priroÄenih anomalija s poveÄanom smrtnoÅ”Äu novoroÄenÄadi i dojenÄadi, Å”to skrb za njih Äini teÅ”kom za obitelj, lijeÄnike primarne zdravstvene skrbi i specijaliste. Oko 28% djece roÄene s trisomijom 13 umire tijekom prvog tjedna života. Srednje oÄekivano trajanje života je oko 2,5 dana. Prikazujemo 12-godiÅ”nju djevojÄicu, najduže živuÄu bolesnicu s Patauovim sindromom u Hrvatskoj, koju pratimo od roÄenja do njezine sadaÅ”nje dobi od 12 godina. Konvencionalni pristup zasnovan na izostanku intervencije doživio je reviziju, a mi predlažemo promjenu tradicionalnog pogleda na ovo stanje
CHARACTERISTICS OF CHILDREN TUBERCULOSIS IN UNIVERSITY HOSPITAL CENTRE SPLIT FROM 1990 TO 2012
Tuberkuloza u djeÄjoj dobi posebna je bolest po svojim epidemioloÅ”kim i kliniÄkim osobitostima. NajuÄinkovitija mjera u suzbijanju Å”irenja bolesti jest brzo otkrivanje te neodgodivo i uÄinkovito lijeÄenje oboljelih. Kako najveÄi dio djece ima mikroskopski negativne iskaÅ”ljaje, brzo postavljanje dijagnoze može biti problem. U ovom radu prikazali smo uÄestalost, lijeÄenje, dijagnostiku i kliniÄke osobitosti djece lijeÄene u KBC-u Split tijekom 22 godine.Childhood tuberculosis is a unique disease regarding epidemiological and clinical features. The most effective measures to combat the spread of the disease are rapid detection and prompt and effective treatment. As most of the children have negative sputum microscopy, rapid diagnosis can be challenging. In this paper, the data on incidence, treatment, diagnostic and clinical characteristics of children treated for tuberculosis in the University Hospital Centre Split during 22 years are presented