The 42nd Symposium Chromatographic Methods of Investigating Organic Compounds : Book of abstracts

The 42nd Symposium Chromatographic Methods of Investigating Organic Compounds : Book of abstracts. June 4-7, 2019, Szczyrk, Polan

The impact of intraoperative antiseptic nasal irrigation during endoscopic sinus surgery on early postoperative results

The main objective of the study was to determine the validity of intraoperative antiseptic treatment during endoscopic sinus surgery and the impact of such a treatment on the postoperative outcomes. Fifty-five patients with chronic sinusitis, qualified for surgical treatment were enrolled into the trial. It was designed as a prospective, randomized, blinded study. The surgical procedures were performed on both sides, in the same scope. In the next stage, after opening, one side was flushed with saline solution, and the other side with octenidine solution. The analysis showed a statistically significant reduction in postoperative crusting measured using the Lund-Kennedy scale between the test and the control group. Intraoperative lavage of the paranasal sinuses in both control and study group showed an effect on decreasing the total number of positive postoperative cultures relative to preoperative ones. Study showed a beneficial effect of the intervention consisting in rinsing with Octenisept on the reduction of crusting in the postoperative assessment

Wpływ śródoperacyjnego leczenia antyseptycznego w trakcie endoskopowej operacji zatok na wczesne wyniki pooperacyjne

Głównym celem niniejszej pracy było określenie zasadności śródoperacyjnego leczenia antyseptycznego w trakcie endoskopowej operacji zatok przynosowych oraz ocena wpływu takiego leczenia na wyniki pooperacyjne. Do badania włączono 55 chorych na przewlekłe zapalenie zatok, zakwalifikowanych do leczenia operacyjnego. Jest to prospektywne badanie randomizowane, zaślepione. Zabiegi chirurgiczne wykonywano obustronnie, w tym samym zakresie. W kolejnym etapie, po otwarciu zatoki przynosowej, jedną stronę płukano roztworem soli, a drugą roztworem oktenidyny. Analiza wykazała istotną statystycznie redukcję strupienia pooperacyjnego mierzonego w skali Lund-Kennedy między grupą badaną a kontrolną. Zarówno w grupie kontrolnej, jak i badanej, wykazano większy wpływ śródoperacyjnego płukania zatok przynosowych na zmniejszenie ogólnej liczby dodatnich wyników posiewów pooperacyjnych w stosunku do płukania przedoperacyjnego. Badanie wykazało korzystny wpływ zabiegu polegającego na płukaniu Octeniseptem na redukcję strupienia w ocenie pooperacyjnej

Comparison of quality of life before and after open septorhinoplasty with the WHOQOL-BREF questionnaire

Introduction: The study aimed to assess the influence of rhinoplasty on the quality of different aspects of life. The study group included 79 patients with congenital or posttraumatic nasal deformities (38 males, 41 females) aged from 17 to 49 (mean age 20 years) with open septorhinoplasty. Materials and Methods: Quality of life was assessed before and 3 months after surgery, using the WHOQOL-BREF questionnaire. Other patient data including demographic data, other surgeries and comorbidities were also registered. Completion of 71 preoperative and 70 postoperative questionnaires was accomplished. R esults showed statistically significant differences in the quality of life in all domains. Discussion and conclusion: Based on the conducted studies and after analysis of available literature, it may be concluded that functional and plastic surgeries including septorhinoplasty have an influence on the quality of life. To control postoperative results, tools evaluating this aspect should be used

Early or late tracheotomy in patients after multiple organ trauma

Introduction: Prolonged mechanical ventilation in patients after multiple organ trauma is an indication for a tracheotomy procedure being performed i.a. to ensure proper hygiene of patient’s airways. Recommendations regarding the optimum timing for the procedure remain ambiguous. Procedures performed before post-operative day 10 are beneficial for the further course of the treatment and patient’s health. Aim: The main objective of the study was to analyze the relationship between the timing of tracheotomy and the length of mechanical ventilation in patients with multiple organ trauma. Secondary objectives included the assessment of the relationships between the timing of tracheotomy and the lengths of intensive care unit (ICU) stay and total hospitalization as well as the incidence of pneumonia and mortality. Material and methods: A retrospective analysis was carried out in 543 patients in whom tracheotomy had been performed at the Clinical Intensive Care Unit of the Military Institute of Medicine in years 2015–2019. Patients were divided into two groups: (1) those subjected to early tracheotomy (prior to hospitalization day 10); and (2) those subjected to late tracheotomy (at day 10 or later). Results: Duration of mechanical ventilation was shorter in patients subjected to early tracheotomy (by 20.3 days on average). The ICU stay and overall hospitalization lengths were also significantly shorter (by the average of 39.4 and 43.1 days, respectively). The mortality rate in patients subjected to early tracheotomy was lower (2%) than in those subjected to late tracheotomy (9%). Pneumonic complications were more common in patients subjected to tracheotomy at hospitalization day 10 or later. Conclusions: Tracheotomy performed within up to 10 days of hospitalization significantly shortens the lengths of mechanical ventilation, ICU stay, and total hospitalization while simultaneously reducing the risk of pneumonia. No correlation has been observed between the timing of tracheotomy and patient mortality rates