3,274 research outputs found
Sherman Antitrust Act Jurisprudence and Federal Policy-Making in the Formative Period, 1890-1914
Sequential measurement of multidimensional transducers technical report no. 431
Application of sequential decoding algorithm to measurement problem
A new test procedure of independence in copula models via chi-square-divergence
We introduce a new test procedure of independence in the framework of
parametric copulas with unknown marginals. The method is based essentially on
the dual representation of -divergence on signed finite measures. The
asymptotic properties of the proposed estimate and the test statistic are
studied under the null and alternative hypotheses, with simple and standard
limit distributions both when the parameter is an interior point or not.Comment: 23 pages (2 figures). Submitted to publicatio
Healthy Skin Naturally
This case focuses on a start-up business trying to find a profitable nicheâ in the skin care market in southern California. Entering a highly competitive industry, Healthy Skin Naturally is trying to determine the proper sales, distribution and promotional strategies to attain their sales goal of $500,000 in the next three years. Over the time that the products have been produced, the owners report that the âfeedback from users tell us that they are all very effectiveâ; itâs the opinion of the owners of Healthy Skin Naturally that price is a secondary factor to buyers as long as the products are effective in helping solve skin problems. Covering a geographic area from Santa Barbara to San Diego, the owners are targeting white collar professional women aged 35 to 70, as well as teenage acne sufferers and men of all ages. This case would be appropriate for sophomore-junior level students. The case can be taught in 2 to 3 hours and expected to require 3-5 hours of outside preparation by students. Research into skincare issues might be helpful before attempting this case
Financial contagion in real economy: The key role of policy uncertainty
© 2020 John Wiley & Sons Ltd This paper studies the spread of the Subprime Crisis and the European Sovereign Debt Crisis from Eurozone countries to the real economy by examining 10 sectors in major developed and emerging stock markets. First, we employ Cappiello et al., Journal of Financial Economics, 2006, 4, 537â572 model and copula functions to detect and cross-check the correlations and the contagion thereafter. Second, we uncover evidence of correlation behaviour between policy uncertainty indexes and stock market returns. The results demonstrate that no country and sector was immune to spillover effects, highlighting the limited effectiveness of policy makers for both the Subprime Crisis and the European Sovereign Debt Crisis. The empirical application provides evidence of significant volatility and tail dependence from the financial sector to many real sectors in the U.S. economy. Additionally, there is clear evidence that certain sectors, particularly Healthcare, Telecommunications, Utilities and Technology, were less severely affected by the crisis, as observed by Baur, Journal of Banking & Finance, 2011, 36, 2680â2692
Strong Approximation of Empirical Copula Processes by Gaussian Processes
We provide the strong approximation of empirical copula processes by a
Gaussian process. In addition we establish a strong approximation of the
smoothed empirical copula processes and a law of iterated logarithm
Reply to comment by S. P. Ferguson and C. D. Rennie on âA mechanistic model linking insect (Hydropsychidae) silk nets to incipient sediment motion in gravelâbedded streamsâ
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/112221/1/jgrf20397.pd
Influence of Sex/Gender and Race on Responses to Raltegravir Combined With Tenofovir-Emtricitabine in Treatment-Naive Human Immunodeficiency Virus-1 Infected Patients: Pooled Analyses of the STARTMRK and QDMRK Studies.
BACKGROUND: Antiretroviral therapy in human immunodeficiency virus (HIV)-infected women and blacks merits particular scrutiny because these groups have been underrepresented in clinical trials.
METHODS: To document the effects of raltegravir across sex and racial lines, we conducted a pooled subgroup analysis of the efficacy and safety of raltegravir 400 mg BID plus tenofovir-emtricitabine by sex (women vs men) and self-identified race (black vs non-black) using phase 3 studies in treatment-naive patients.
RESULTS: Study participants included 42 black women, 102 non-black women, 48 black men, and 477 non-black men. Clade B infections were less common in women (43.8%) than men (84.6%) and in blacks (45.6%) than non-blacks (80.5%). Baseline CD4 counts were â€200 cells/”L in 52.2% of blacks and 31.6% of non-blacks. Black men had the largest proportion of patients with baseline CD4 counts/”L and the highest nontreatment-related discontinuation rate among the 4 sex-by-race subgroups. Human immunodeficiency virus-ribonucleic acid levels/mL were achieved at week 48 in 92.7% (95% confidence interval [CI], 80.1-98.5) of black women, 93.6% (95% CI, 86.6-97.6) of non-black women, 82.9% (95% CI, 67.9-92.8) of black men, and 91.4% (95% CI, 88.4-93.8) of non-black men. Serious clinical adverse events were reported in 9.0% of women versus 8.8% of men and in 11.1% of blacks versus 8.5% of non-blacks.
CONCLUSIONS: In this post hoc analysis of patients with previously untreated HIV-1 infection receiving raltegravir plus tenofovir-emtricitabine, generally comparable results were achieved across sex and racial subgroups. However, black men had a lower response rate than either black women or non-black men, partially attributable to lower baseline CD4 counts and higher discontinuation rates
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