16 research outputs found
Thinking twice before using the LMA for obese and older patients - A prospective observational study
10.4172/2155-6148.1000283Journal of Anesthesia and Clinical Research4
HIV-1 pol gene polymorphism and transmitted drug resistance (TDR) in chronically infected HIV-1 antiretroviral treatment naïve patients in South India
Recommended from our members
Occult HBV infection in HIV-infected adults and evaluation of pooled NAT for HBV.
The study aimed to determine the prevalence of occult hepatitis B virus infection among HIV-infected persons and to evaluate the use of a pooling strategy to detect occult HBV infection in the setting of HIV infection. Five hundred and two HIV-positive individuals were tested for HBV, occult HBV and hepatitis C and D with serologic and nucleic acid testing (NAT). We also evaluated a pooled NAT strategy for screening occult HBV infection among the HIV-positive individuals. The prevalence of HBV infection among HIV-positive individuals was 32 (6.4%), and occult HBV prevalence was 10%. The pooling HBV NAT had a sensitivity of 66.7% and specificity of 100%, compared to HBV DNA NAT of individual samples. In conclusion, this study found a high prevalence of occult HBV infection among our HIV-infected population. We also demonstrated that pooled HBV NAT is highly specific, moderately sensitive and cost-effective. As conventional HBV viral load assays are expensive in resource-limited settings such as India, pooled HBV DNA NAT might be a good way for detecting occult HBV infection and will reduce HBV-associated complications
Recommended from our members
Immune activation is associated with poor CD4 reconstitution: a study from South India
Pattern of HIV-1 drug resistance mutations among patients failing thymidine analogue and non-thymidine analogue based first-line failure in South India
Archived drug resistance profile among suppressed HIV patients using conventional and sensitive allele specific PCR in Tenofovir experienced patients in South India
Prevalence and risk factors associated with immunological non-response in HIV-1 infected patients treated with NNRTI based first line drugs in South India
Recommended from our members