866 research outputs found
Gewoon artrose
Gewoon artrose. Is artrose inderdaad zo gewoon? Ja, helaas wel. Iedereen weet wel
een familielid of bekende op te noemen die geopereerd is voor artrose, en als u in
uw omgeving navraagt, blijken er nog veel meer mensen last van te hebben.
Artrose, in de volksmond gewrichtslijtage, is een heel gewone aandoening die
veel voorkomt, vooral op oudere leeftijd, die niet levensbedreigend is. “Ach, het is de
ouderdom, ik moet er maar mee leren leven” zal u niet onbekend in de oren klinken.
Gewoon, een hinderlijke aandoening. Maar ondanks dat artrose, èn de last die mensen
daarvan hebben, zoveel voorkomt, hebben we op heel veel gewone vragen over artrose
nog geen antwoord.
Vandaag aanvaard ik mijn benoeming op een bijzondere leerstoel voor deze zeer
gewone aandoening, de eerste in Nederland. Ik ga u de komende drie kwartier laten
zien waarom deze nieuwe leerstoel noodzakelijk is, èn wat u van mij en mijn team aan
inspanningen mag verwachten.
Rede,
uitgesproken ter gelegenheid
van het aanvaarden van het ambt
van bijzonder hoogleraar met als leeropdracht
Artrose en gerelateerde aandoeningen,
aan het Erasmus MC, faculteit van de
Erasmus Universiteit Rotterdam
op 16 december 201
Osteoarthritis subpopulations and implications for clinical trial design
Treatment guidelines for osteoarthritis have stressed the need for research on clinical predictors of response to different treatments. However, identifying such clinical predictors of response is less easy than it seems, and there is not a given classification of osteoarthritis subpopulations. This review article highlights the key methodical issues when analyzing and designing clinical studies to detect important subgroups with respect to treatment effect. In addition, we discuss the main osteoarthritis subpopulations and give examples of how specific treatment effects in these subpopulations have been assessed
Hip Pain in general Practice: exploiration and classification
Musculoskeletal diseases are the second most costly group of disorders in
primary care in the Netheriands. Of the musculoskeletal disorders, hip
problems occur most frequently in the aged. Therefore, in the coming decades,
prevalence of hip disorders, of which an important part is attributed to osteoarthritis
of the hip,' is expected to increase due to ageing of the population. The report
'Public Health Status and Forecasts 1997' predicts that by the year 2015 the incidence
of osteoarthritis will have increased 36% compared to the current incidence.'
Besides generating high costs, hip disorders have a major impact on the life of
individuals, not only due to the presence of pain, but also because of tl,e adverse
effects on the mobility and daily activities of the elderly. A recent Dutch study in
the open population aged 55 years and over and living independently revealed that
16.6% of the women and 8.3% of the men reported hip pain.' In the Netherlands,
the general practitioner is the fIrst physician who is consulted and therefore plays an
important role in the management of these disorders. Optimal management, however,
requires accurate diagnosis. The Dutch College of General Practitioners has
published national gnidelines for the diagnosis, treatment and referral of many disorders
in general practice.' For hip disorders, however, no such guidelines are yet
available. International (ICPC) codes for several hip disorders in general practice
have been introduced', but these lack clear guidelines as to what clinical criteria constitute
these conditions. The possibility in the ICPC to code a hip problem as 'unspecifIed'
is eagerly accepted by general practitioners; at least one tlilld of tl,e patients
with hip complaints receives no specifIc diagnosis
Obesity and hip osteoarthritis [1]
To the Editor:We read with interest the editorial by Gelber that appeared in the February issue of The American Journal of Medicine. The author presents a good overview of the effects and known risk factors of osteoarthritis, discussing the influence of obesity on hip osteoarthritis. We would like to add to this by reporting a finding from our recent review of the topic.<br/
Obesity and hip osteoarthritis [1]
To the Editor:We read with interest the editorial by Gelber that appeared in the February issue of The American Journal of Medicine. The author presents a good overview of the effects and known risk factors of osteoarthritis, discussing the influence of obesity on hip osteoarthritis. We would like to add to this by reporting a finding from our recent review of the topic.<br/
Prognostic factors for progression of clinical osteoarthritis of the knee: A systematic review of observational studies
Introduction: We performed a systematic review of prognostic factors for the progression of symptomatic knee osteoarthritis (OA), defined as increase in pain, decline in physical function or total joint replacement. Method: We searched for avail
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